Clinical

Automated ventilatory burden can effectively assess obstructive sleep apnea (OSA) severity, estimate cardiovascular (CVD) mortality, and may present a promising alternative to apnea-hypopnea index (AHI).

Study results suggest the greatest risk for Clostridioides difficile infection was observed with use of clindamycin while the lowest risk was observed with doxycycline and minocycline.

Patients with advanced or metastatic non–small cell lung cancer (NSCLC) were able to specify a 1-point threshold when describing meaningful symptom change, for better or worse, that helped illustrate their symptom experience.

Perampanel was found effective and safe for prolonged use in children with epilepsy, according to one study.

FDA approves updated COVID-19 booster vaccines; low donor turnout and climate disasters result in a national blood shortage; minority patients discouraged by lack of doctor diversity.

Ryan Haumschild, PharmD, MS, MBA, director of pharmacy at Emory Winship Cancer Institute, discusses treatment options available to patients with rare diseases, as well as the challenges these patients and their pharmacists face in accessing these treatments.

As patients’ atopic dermatitis (AD) worsens, the risk of inflammatory bowel disease, Crohn disease, and ulcerative colitis increases.

There are multiple treatment options becoming available for diffuse large B-cell lymphoma, but more work needs to be done to understand their efficacy and in what lines of therapy they should be used.

Boys who smoke in their early teens increase risk of their future children developing asthma, obesity, and low lung function, a study suggests.

New research suggests an association between gestational diabetes history and mortality over 30 years, regardless of whether it manifests into type 2 diabetes.

The LEAP-017 trial results presented at ESMO GI 2023 are explored by Dr Marshall.

Discussion on treatment algorithms as well as the impact of sebum in acne patients.

An overview on adverse effects for topical clascoterone, minocycline, and trifarotene

The highest proportions of patients with severe ocular impairment at baseline showed greater improvements in symptom severity on ravulizumab in comparison with placebo after 26 weeks.

New research suggests conventional fractionated and hypofractionated proton postmastectomy radiotherapy (PMRT) yield similar tolerability and complication rates for patients following mastectomy.

A study found acute myeloid leukemia (AML) salvage therapy was independently associated with early mortality compared with frontline therapy, suggesting that algorithms measuring quality of care should incorporate risk mortality indices that factor in disease characteristics and treatment status.

Two abstracts presented at the 2023 International Epilepsy Congress evaluated early electroencephalography (EEG) monitoring in children with seizures and encephalopathy.

Patients who have with sickle cell disease (SCD) could have a slower processing speed and higher cerebral blood flow compared with controls.

A year of research emphasizes the significance of collaboration, standardized approaches, and targeted therapies in rare pulmonary diseases.

Important factors associated with hospital readmission of children with acute respiratory distress syndrome (ARDS) included an index hospitalization of 14 days or longer and having chronic medical conditions during the index admission.

Fecal microbiota profiles were observed to be significantly different among patients with melanoma and controls, as well as those with early-stage and late-stage melanoma.

The panel provides their closing thoughts as they examine the stigmas and unmet needs surrounding schizophrenia.

Future therapies for the treatment of schizophrenia are explored by a panel of key opinion leaders.

After treatment, the mental health and sleep quality of mothers in the mild atopic dermatitis (AD) group improved significantly, while those of mothers in the moderate and severe AD groups only showed some improvement.

The review summarized existing evidence around short- and long-term treatment-related toxicities among adolescents and young adults (AYAs), as well as gaps in care guidelines for AYA survivors of lymphoma.

Hidradenitis suppurativa (HS) in elderly patients is not unusual and may be associated with male sex, study suggests.

The investigation evaluated if symptom signatures of myasthenia gravis exacerbations could be evaluated using real-world data gathered via a smartphone-based research platform.

Out of several factors, surgical complications were the only factor independently associated with emergency department (ED) readmission among patients who underwent surgery for ovarian carcinoma.

Erin Gillaspie, MD, MPH, FACS, a faculty member of Vanderbilt University Medical Center’s Department of Thoracic Surgery, discussed improvements in lung cancer outcomes due to new screenings and therapies.