Colorectal Cancer

Latest News
February 26th 2025

Cetuximab Plus Chemotherapy May Improve Colorectal Cancer Outcomes

February 24th 2025

Eating Yogurt May Help Reduce Colorectal Cancer Risk

February 21st 2025

Specialists Boost Patient Acceptance of Longer Colonoscopy Intervals

February 17th 2025

Calcium Intake Linked to Reduced Colorectal Cancer Risk, Study Finds

February 12th 2025

Evaluation System Reduces Ineffective Hospital Days in Colorectal Cancer Care

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February 18th 2025

Tackling Colorectal Cancer Care Inequities Through Patient Advocacy Groups

February 7th 2025

Patients With Colorectal Cancer Seek More Say in Treatment, Face Financial Barriers

October 21st 2024

A Look at Cancers Where Biomarkers Are Needed

May 24th 2024

Dr Ajay Goel Explains Effectiveness of Liquid Biopsies, Tissue-Based Biomarkers in Treating CRC

May 21st 2024

Dr Ajay Goel Discusses New Methods of Testing for EOCRC, Recurrence

August 28th 2023

Botensilimab and Balstilimab in Refractory Microsatellite Stable (MSS) mCRC

August 21st 2023

Impact of Microsatellite Stability in Metastatic Colorectal Cancer

April 4th 2023

Utilizing RWE to Address Unmet Needs for CRC

March 14th 2023

ASCO GI 2023: SUNLIGHT Study

December 24th 2022

Neoadjuvant Immunotherapy Promising in CRC, but Long-term Data Needed, Says Dr Kristen Ciombor

More News

Flatiron Health, Exact Sciences Announce Deal to Speed Evidence Generation With MRD Test
February 6th 2025

Flatiron Health, Exact Sciences Announce Deal to Speed Evidence Generation With MRD Test

AJMC Staff
The companies announced the deal in a statement February 5, 2025, noting that the first patient had enrolled in a prospective clinical study using the test to monitor cancer recurrence across multiple solid tumor types.
United by Unique | Image credit: UICC
February 4th 2025

On World Cancer Day, NCCN Patient Advocates Share What Makes Their Journeys Unique

Mary Caffrey
World Cancer Day also marks the start of the ‘United by Unique’ campaign, which seeks to highlight how each person’s journey with cancer is unique, even though the patients, caregivers, and health care teams who are touched by cancer are united by shared goals.
Colorectal cancer - mi_viri - stock.adobe.com.
February 4th 2025

How Prior Malignancy Impacts Survival in Metastatic Colorectal Cancer

Pearl Steinzor
New data showed that prior malignancy may influence survival outcomes in patients with metastatic colorectal cancer, highlighting the need for standardized treatment approaches.
CRC detection | Image credit: Ahmet Aglamaz - stock.adobe.com
January 23rd 2025

Unlocking Early Colorectal Cancer Detection With Artificial Intelligence

Pearl Steinzor
With high-sensitivity and strong negative predictive value, this artificial intelligence (AI)-powered tool enhances early colorectal cancer (CRC) detection and risk stratification in primary care.
Waist circumference measurement | Image credit: thatinchan - stock.adobe.com
January 21st 2025

Obesity Metrics May Better Reflect CRC Link Than BMI

Pearl Steinzor
Waist circumference and waist-to-hip ratio show stronger links to colorectal cancer (CRC) than body mass index (BMI), a new study has found.
FDA Approved
January 17th 2025

FDA Approves Sotorasib Plus Panitumumab for KRAS G12C-Mutated Metastatic CRC

Julia Bonavitacola
The combination treatment specifically targets KRAS-mutated metastatic colorectal cancer (CRC) to improve progression-free survival.
Blood sample collection | Image credit: luchschenF - stock.adobe.com
January 16th 2025

Prioritizing Blood-Based Colorectal Cancer Tests May Lead to Higher Costs, Worse Outcomes

Pearl Steinzor
Despite the availability of several noninvasive tests for colorectal cancer, prioritizing blood-based tests may result in higher costs and worse population-level outcomes.
CRC concept | Image credit: SewcreamStudio - stock.adobe.com
January 13th 2025

Ethnic Disparities Identified in Colorectal Cancer Diagnoses, Study Finds

Pearl Steinzor
New research examines how ethnicity impacts colorectal cancer diagnosis, early-onset colorectal cancer (CRC) prevalence, and stage at diagnosis.
Colorectal cancer | Image credit: mi_viri - stock.adobe.com
January 9th 2025

Limited Benefits of ctDNA Testing in Colorectal Cancer Surveillance, Study Finds

Pearl Steinzor
Adding serial circulating tumor DNA (ctDNA) assays to standard of care imaging surveillance had limited clinical benefits in patients with resected colorectal cancer (CRC).
FIT test CRC - Paul Maguire - stock.adobe.com
January 6th 2025

When to Stop Colorectal Cancer Screening?

Pearl Steinzor
How does age, sex, comorbidity, and screening history influence the cost-effectiveness of continuing colorectal cancer (CRC) screening in older adults?
Top 5 CRC Articles of 2024
December 27th 2024

Top 5 Most-Read Colorectal Cancer Articles of 2024

Julia Bonavitacola
The most-read articles focused on the new colonoscopy guidelines, the relationship between diabetes and colorectal cancer, and the rate of colonoscopies performed.
FDA Approved
December 20th 2024

FDA Approves Encorafenib With Cetuximab and mFOLFOX6 for Metastatic CRC

Julia Bonavitacola
Patients with the BRAF V600E mutation and metastatic colorectal cancer (CRC) can be treated with a combination of encorafenib with cetuximab and mFOLFOX6.
Colorectal cancer | Image credit: SewcreamStudio - stock.adobe.com
December 18th 2024

Bevacizumab Biosimilar Equally Effective in Metastatic Colorectal Cancer

Julia Bonavitacola
Compared with originator bevacizumab, the biosimilar version of bevacizumab had equal efficacy when used to treat metastatic colorectal cancer.
Top 5 News Articles 2024
December 16th 2024

Top 5 Most-Read News Articles of 2024

Julia Bonavitacola
In 2024, the most-read news articles published on the website of The American Journal of Managed Care® included FDA approvals, colonoscopy guidelines, and a list of drugs facing shortages.
Colorectal cancer | Image credit: Dr_Microbe - stock.adobe.com
December 13th 2024

Treatment Combinations Based in Immune Checkpoint Inhibitors Provide Survival Benefits in CRC

Julia Bonavitacola
Patients with heavily pretreated microsatellite stable metastatic colorectal cancer (CRC) had survival benefits after using combinations based in immune checkpoint inhibitors.
Stool test | Image credit: luchschenF - stock.adobe.com
December 10th 2024

Mass-Mailed Stool Tests Helped Improve Odds of Adherence, CRC Test Return

Julia Bonavitacola
Older adults on Medicare Advantage had improved adherence and odds of a test return when a stool test was mailed to them for screening of colorectal cancer (CRC).
Rectal cancer | Image credit: Anatomy Insider - stock.adobe.com
December 6th 2024

Rectal Cancer Has Better Short-Term Outcomes With Robotic Abdominoperineal Resection

Julia Bonavitacola
Laparoscopic abdominoperineal resection had worse short-term outcomes when compared with robotic resection, according to a review.
Respiratory system | Image credit: PIC4U - stock.adobe.com
December 2nd 2024

CRC Incidence Risk Associated With Changes in Cardiorespiratory Fitness

Julia Bonavitacola
Changes in cardiorespiratory fitness from youth to adulthood was associated with colorectal cancer (CRC) incidence risk.
Colorectal cancer | Image credit: Sebastian Kaulitzki - stock.adobe.com
November 25th 2024

Racial, Ethnic Disparities Persist in Mortality for Patients With Early-Onset CRC

Julia Bonavitacola
Native Hawaiian and non-Hispanic Black individuals had the highest burden of mortality among patients with early-onset colorectal cancer (CRC).
VUMC logo | Image: VUMC
November 21st 2024

Innovating Cancer Care Through Equity and AI: Vanderbilt’s Vision

Maggie L. Shaw
Coverage from the IVBM event with Vanderbilt-Ingram Cancer Center in Nashville, Tennessee.
FIT | Image credit: Paul Maguire - stock.adobe.com
November 19th 2024

Commercial FIT Capable of Similar Diagnostic Results as New Stool DNA Test

Julia Bonavitacola
Lowering the positivity threshold for a high-quality fecal immunochemical test (FIT) can increase sensitivity of noninvasive screening for colorectal cancer in a more economical way.
Colorectal cancer | Image credit: Dr_Microbe - stock.adobe.com
November 11th 2024

Smoking a Risk Factor for CRC in Black African Patients

Julia Bonavitacola
Risk factors of colorectal cancer (CRC) include both smoking and a combination of smoking and alcohol in African patients.
CRC | Image credit: mi_viri - stock.adobe.com
November 7th 2024

Disparities Persist in CRC Screening, Management Between High-, Low-Income Countries

Julia Bonavitacola
Low- and high-income countries had significant disparities in screening for colorectal cancer (CRC) due to limited access to screening and treatment in low-income countries.
Colorectal cancer | Image credit: Sebastian Kaulitzki - stock.adobe.com
November 5th 2024

Overall, Progression-Free Survival in Colon Cancer Indicated Through Visceral Proteins

Julia Bonavitacola
Ratios of visceral proteins can act as independent indicators for both overall and progression-free survival in patients with colon cancer.
Jeffrey Reese Contributor
November 4th 2024

Contributor: An Urgent Call to Action as Colorectal Cancer Rates Skyrocket Among Young People

Jeffrey Reese
As rates of CRC skyrocket in young individuals, means of addressing the growing problem must be considered.
Blood test | Image credit: angellodeco - stock.adobe.com
October 29th 2024

Net Results Vary When Using Cell-Free DNA Blood Tests for CRC Screening

Julia Bonavitacola
Results could vary between having a net benefit or harm based on the balance between achieving screening in individuals who otherwise wouldn’t and using cell-free DNA blood tests in favor of more effective methods of screening for colorectal cancer (CRC).
Robot-assisted surgery | Image credit: Monopoly919 - stock.adobe.com
October 25th 2024

Robotic Systems Possess Positive Outcomes, Safety in Colorectal Surgery

Julia Bonavitacola
Surgery for colorectal cancer has been both positive and challenging when using robotic-assisted surgeries.
Fecal immunochemical test | Image credit: Paul Maguire - stock.adobe.com
October 22nd 2024

FIT Completion, Yield Rates in CRC Screening Similar After New Screening Guidelines

Julia Bonavitacola
Patients were found to have similar completion and yield rates for the fecal immunochemical test (FIT) at both 45 years and 50 years, making screening for colorectal cancer (CRC) effective in younger patients.
Calculating cost | Image credit: joyfotoliakid - stock.adobe.com
October 10th 2024

Cost Effectiveness Varies in TAS-102 Plus Bevacizumab Third Line Treatment

Julia Bonavitacola
Patients with refractory metastatic colorectal cancer could use trifluridine/tipiracil (TAS-102) plus bevacizumab as a cost effective third line treatment in China but the same was not found in the United States and United Kingdom.
Colorectal cancer | Image credit: Dr_Microbe - stock.adobe.com
October 7th 2024

CRC Screening Increases in Patients Aged 45 to 49 After USPSTF Recommendation

Julia Bonavitacola
The updated guidelines from the US Preventive Services Task Force (USPSTF) have led to an increase in screening for colorectal cancer (CRC) in individuals aged 45 to 49 years.
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