The AJMC® clinical page includes all the published content across AJMC.com, The American Journal of Managed Care® and Evidence-Based Oncology™ on a variety of specialties, including dermatology, cardiology, oncology, and rheumatology.
April 18th 2025
From Crohn disease to uncomplicated urinary tract infections and beyond, the FDA issued several high-impact drug approvals last month.
Claims Data Hint at Unmet Needs Among Patients With Severe Asthma, COPD
October 11th 2023Vast claims databases can yield valuable information about the unmet medical needs of patients with chronic obstructive pulmonary disease (COPD) and severe asthma, and those insights point to areas that can be improved by engaging and educating clinicians.
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CHEST Posters Show Asthma, COPD Exacerbations Slashed After Single-Inhaler Triple Therapy
October 11th 2023Two posters presented at the CHEST Annual Meeting 2023 showed how real-world exacerbation rates in asthma and chronic obstructive pulmonary disease (COPD) dropped after patients started using a single inhaler that delivers triple therapy.
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Contributor: Advancing Breast Cancer Treatment—The Role of Clinical Trials and the Path Ahead
October 11th 2023Clinical studies have transformed how breast cancer is prevented, identified, and treated. Successful clinical trials improve patient outcomes, so trial administrators must ensure participants receive appropriate support at trial enrollment.
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gMG Imposes an Enormous Economic Burden on Patients
October 10th 2023Qualitative interviews were conducted and a web-based quantitative survey was administered to have a clearer understanding of the economic impact of social determinants of health on patients living with generalized myasthenia gravis (gMG).
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Avidity Biosciences Gains FDA Orphan Drug Designation for Patients With DMD
October 9th 2023Sarah Boyce, president and CEO at Avidity Biosciences, discusses her leading role at the company, as well as antibody oligonucleotide conjugate drug, AOC 1044, currently in development for Duchenne muscular dystrophy (DMD) with mutations amenable to exon 44 skipping (DMD44).
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Lung Effects of Particulate Matter Exposure in WTC First Responders Still Redound Decades Later
October 9th 2023New research explores the risk factors for lung disease in firefighters who were exposed to particulate matter when responding to the attacks on the World Trade Center (WTC) on September 11, 2001, as well as interventions that may mediate inflammatory responses.
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Experts Debate Terminology and Treatment of Asthma-COPD Overlap
October 9th 2023As evidenced by a debate at the CHEST Annual Meeting 2023, the pulmonology community disagrees on whether the overlap of asthma and chronic obstructive pulmonary disease (COPD) is a distinct entity and how best to treat it.
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Bridging RT Before CAR T-Cell Therapy Can Benefit Patients With R/R DLBCL
October 6th 2023Researchers found that patients with relapsed/refractory (R/R) diffuse large B-cell lymphoma (DLBCL) may benefit from bridging radiation therapy (RT) ahead of receiving chimeric antigen receptor (CAR) T-cell therapy.
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FDA Grants Fast Track Designation to IDE161 for Select Pretreated BRCA1/2-Mutated HR+ Breast Cancer
October 6th 2023The FDA has granted fast track designation to IDE161 for use in adult patients with advanced or metastatic hormone receptor–positive, HER2-negative breast cancer harboring BRCA1/2 mutations who have progressed after at least 1 hormonal therapy, a CDK4/6 inhibitor, and a poly (ADP-ribose) polymerase inhibitor.
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