Parkinson Disease

The AJMC® Parkinson Disease compendium is a comprehensive resource for clinical news and expert insights for progressive nervous system disorder, which affects movement and often includes tremors.

Latest News

Air Pollution Linked to PD, With Mississippi-Ohio River Valley Region Most Affected
Air Pollution Linked to PD, With Some Parts of US More Affected Than Others

February 24th 2023

The latest research to look at the links between Parkinson disease and air pollution said the Rocky Mountain region and the Mississippi-Ohio River Valley appeared to be the most affected.

PD Worsens QOL, Increases Depression in Men More Than Women in the Southeast
PD Worsens QOL, Increases Depression in Men More Than Women in the Southeast

February 17th 2023

Image of a diverse group of patients
Certain Patient Groups Continue to Be Underrepresented in PD Studies in the Netherlands

February 4th 2023

graphic of a brain
Creating a Metric to Determine Social Functioning in Parkinson Disease

February 1st 2023

Woman in meditation position
Mindfulness Training May Improve Outcomes for People With Parkinson Disease

January 30th 2023

More News

Study Suggests Brain Tissue Iron May Track Cognitive Involvement in Parkinson
March 15th 2020

Study Suggests Brain Tissue Iron May Track Cognitive Involvement in Parkinson

Alison Rodriguez
Changes in brain tissue iron relate to poorer cognition in Parkinson disease, according to a recent study.
Patients With Parkinson Disease at Increased Risk of Vision, Eye Issues, Study Shows
March 12th 2020

Patients With Parkinson Disease at Increased Risk of Vision, Eye Issues, Study Shows

Matthew Gavidia
Patients with Parkinson disease were found to be more likely to experience vision and eye issues, such as blurry vision, dry eyes, trouble with depth perception, and problems adjusting to rapid changes in light, compared with people without the disorder, according to study findings.
Motor and Non-Motor Wearing-off Impact Quality of Life in Parkinson, Study Finds
March 2nd 2020

Motor and Non-Motor Wearing-off Impact Quality of Life in Parkinson, Study Finds

Alison Rodriguez
A recent study aiming to evaluate the impact of motor and non-motor wearing-off—a common phenomenon in Parkinson disease (PD)—found that the fluctuations have an impact on the activities of daily living and quality of life, with non-motor wearing-off having the greater impact.
Study Finds Tai Chi Exercises May Prove Effective for Patients With Parkinson Disease
February 29th 2020

Study Finds Tai Chi Exercises May Prove Effective for Patients With Parkinson Disease

Alison Rodriguez
In individuals with mild to moderate Parkinson disease, Tai Chi was shown to be a potentially effective meditation technique that may slow down disease progression, according to study findings.
Study Suggests Table Tennis Exercises May Benefit Motor Symptoms in Parkinson Disease
February 26th 2020

Study Suggests Table Tennis Exercises May Benefit Motor Symptoms in Parkinson Disease

Matthew Gavidia
In a preliminary study to be presented at the American Academy of Neurology’s 72nd Annual Meeting, researchers found that patients with Parkinson disease who participated in a table tennis exercise program once a week for 6 months exhibited an improvement in their motor skills.
Adherence Suffers When OOP Drug Costs for Neurologic Disorders Rise, Study Shows
February 20th 2020

Adherence Suffers When OOP Drug Costs for Neurologic Disorders Rise, Study Shows

Matthew Gavidia
Higher out-of-pocket (OOP) drug costs for 3 common neurologic conditions—Parkinson disease, Alzheimer disease, and peripheral neuropathy—were associated with lower medication adherence among patients, which can potentially intensify symptom burden and result in higher costs.
Results: White Matter Hyperintensities Can Be Predictive Marker in Early Stage Parkinson Disease
February 17th 2020

Results: White Matter Hyperintensities Can Be Predictive Marker in Early Stage Parkinson Disease

Alison Rodriguez
These findings suggest that baseline white matter hyperintensities can act as a predictive marker or therapeutic target for the development of levodopa-induced dyskinesia in patients with early stage Parkinson disease.
What We're Reading: Uptick in Coronavirus Cases; Juul Ads Targeted Children; Motion Technology Aids Rehab
February 13th 2020

What We're Reading: Uptick in Coronavirus Cases; Juul Ads Targeted Children; Motion Technology Aids Rehab

AJMC Staff
China reported a sharp uptick in coronavirus cases; a Massachusetts lawsuit claims Juul advertisements targeted children; motion picture technology is being used in rehab centers.
Palliative Care Improves Quality of Life, Symptom Burden of Patients With Parkinson Disease
February 11th 2020

Palliative Care Improves Quality of Life, Symptom Burden of Patients With Parkinson Disease

Matthew Gavidia
Compared with standard care, patients with Parkinson disease and related disorders who received palliative care exhibited improved quality of life and better symptom burden at 6 months after intervention, according to study findings.
Study Links Cognitive Disability to Greater Disability in Moderate-to-Advanced Parkinson
February 9th 2020

Study Links Cognitive Disability to Greater Disability in Moderate-to-Advanced Parkinson

Alison Rodriguez
Researchers analyzed how cognitive ability relates to ambulatory status in Parkinson.
Novel Technology Found to Distinguish Between Parkinson Disease, Multiple System Atrophy
February 5th 2020

Novel Technology Found to Distinguish Between Parkinson Disease, Multiple System Atrophy

Matthew Gavidia
A novel protein misfolding cyclic amplification technology was able to distinguish between 2 progressive neurodegenerative diseases, Parkinson disease (PD) and multiple system atrophy, signaling potential improvements in diagnosis of PD.
Researchers Say They Have Clue to Early-Onset Parkinson Disease
January 27th 2020

Researchers Say They Have Clue to Early-Onset Parkinson Disease

Allison Inserro
Patients with early-onset Parkinson disease may have been born with disordered brain cells that mishandled dopamine for decades, according to a study released Monday.
Balance Training Shown to Promote Anti-inflammatory Response in Patients With Parkinson Disease, Study Shows
January 24th 2020

Balance Training Shown to Promote Anti-inflammatory Response in Patients With Parkinson Disease, Study Shows

Alison Rodriguez
Balance training of moderate intensity (BT) may increase anti-inflammatory cytokines and neurotrophic factor levels of patients with Parkinson disease (PD), according to study findings.
This Week in Managed Care: January 10, 2020
January 10th 2020

This Week in Managed Care: January 10, 2020

This week, the top managed care stories included cancer deaths falling for the 25th straight year; a study finding no link between talc powder and ovarian cancer; a poll finding 1 in 4 patients with Parkinson disease may be misdiagnosed.
Poll Finds 1 in 4 People With Parkinson Disease Misdiagnosed
January 8th 2020

Poll Finds 1 in 4 People With Parkinson Disease Misdiagnosed

Matthew Gavidia
In a poll of people with Parkinson disease, more than 1 in 4 (26%) participants reported having been misdiagnosed, with a further 21% having to see their general provider 3 times before being referred to a specialist.
Weekly Regimens of Physical, Cognitive Exercises Shown to Slightly Improve Symptoms of Parkinson Disease
December 30th 2019

Weekly Regimens of Physical, Cognitive Exercises Shown to Slightly Improve Symptoms of Parkinson Disease

Matthew Gavidia
The motor and non-motor symptoms of patients with Parkinson Disease were shown to slightly improve with a weekly exercise regimen of physical and cognitive exercises, according to research presented at Future Physiology 2019.
Study Targets Cannabinoid Receptor to Ease Parkinson Symptom of Dyskinesia
December 21st 2019

Study Targets Cannabinoid Receptor to Ease Parkinson Symptom of Dyskinesia

AJMC Staff
The drug, HU-308, is aimed at treating levodopa-induced dyskinesia (LID). The animal study showed that it was as effective as amantadine, the only available treatment for dyskinesias; combining HU-308 with amantadine was also more effective than either drug used alone.
Caregivers of Patients With Recurrent Symptoms of Parkinson Disease Exposed to Greater Financial Burden, Loss of Employment
December 17th 2019

Caregivers of Patients With Recurrent Symptoms of Parkinson Disease Exposed to Greater Financial Burden, Loss of Employment

Matthew Gavidia
Caregivers of patients with Parkinson disease (PD) experiencing symptom recurrence after a period of symptom control, known as OFF periods, reported that PD had a greater impact on their paid employment through variables such as loss of earnings, loss of opportunities, or ability to maintain employment compared with caregivers for patients without OFF periods.
Symptom Control of Parkinson Disease Linked to Ability, Productivity of Employment
December 15th 2019

Symptom Control of Parkinson Disease Linked to Ability, Productivity of Employment

Matthew Gavidia
Study results presented at AMCP Nexus 2019 in National Harbor, Maryland, showed that 65.4% of patients with parkinson disease reported experiencing symptom recurrence, known as OFF periods, which impedes work productivity and employment.
Study Probes Key Receptor Signaling That Goes Awry in Parkinson
December 13th 2019

Study Probes Key Receptor Signaling That Goes Awry in Parkinson

Alison Rodriguez
Dopamine receptor D3 (DRD3) signaling regulates the dynamic of the acquisition of pro-inflammatory and anti-inflammatory features by astrocytes and microglia, favoring microglial activation and promoting neuroinflammation—the pathogenic process leading to neurodegeneration in many disorders, including Parkinson disease, according to a recent study.
Altered Emotional Capability Possibly Linked to Atypical Form of Parkinson
December 7th 2019

Altered Emotional Capability Possibly Linked to Atypical Form of Parkinson

Alison Rodriguez
Alexithymia—the inability of recognizing and verbalizing emotions and distinguishing them from bodily sensations—may be identifiable early on in patients with progressive supranuclear palsy with predominant parkinsonism (PSP-P) and PSP with Richardson’s syndrome (PSP-RS).
Relationship Between Chaperone Proteins, Protein Α-Synuclein Linked to Potential Development of Parkinson Disease
December 4th 2019

Relationship Between Chaperone Proteins, Protein Α-Synuclein Linked to Potential Development of Parkinson Disease

Matthew Gavidia
A disturbed relationship between chaperone proteins and the protein α-synuclein was linked to cell damage and the development of Lewy bodies, which are common in those diagnosed with Parkinson disease, according to study findings.
Study Looks at Biomarker for Parkinson Disease
November 30th 2019

Study Looks at Biomarker for Parkinson Disease

Alison Rodriguez
A study aiming to determine whether blood cells expressing α‐synuclein (α‐syn) can differentiate Parkinson disease (PD) from healthy controls (HC), finding that there is potential usefulness of blood cells expressing α‐syn as a biomarker for PD.
Minimally Invasive Procedure Reduces Tremors in Patients With Parkinson Disease
November 26th 2019

Minimally Invasive Procedure Reduces Tremors in Patients With Parkinson Disease

Matthew Gavidia
A minimally invasive procedure that applies pulses of focused ultrasound to the brain was found to be safe and effective in reducing tremors and improving the quality of life in patients with Parkinson disease and essential tremor, according to research to be presented at the annual meeting of the Radiological Society of North America.
New Molecular Drivers of Parkinson Disease Discovered, Indicating Potential Treatment Innovations
November 21st 2019

New Molecular Drivers of Parkinson Disease Discovered, Indicating Potential Treatment Innovations

Matthew Gavidia
Researchers discovered new molecular drivers of Parkinson disease (PD) and determined their impact on the functions of genes involved in PD, potentially leading to novel treatments, according to study findings.
Game System May Be Effective Rehabilitation Option for Parkinson Disease, Study Finds
November 15th 2019

Game System May Be Effective Rehabilitation Option for Parkinson Disease, Study Finds

Alison Rodriguez
The Leap Motion Controller system used with serious games may be an effective option for a rehabilitation tool for improving coordination, speed of movements, and fine upper limb dexterity in patients with Parkinson disease, according to a recent study, published by the Journal of NeuroEngineering and Rehabilitation.
EPA Proposal to Limit Science Used in Rulemaking Takes Center Stage During Committee Meeting
November 14th 2019

EPA Proposal to Limit Science Used in Rulemaking Takes Center Stage During Committee Meeting

Matthew Gavidia
The EPA proposal to limit science used in rulemaking was discussed by panel members during a hearing held today by the House Committee on Science, Space, and Technology, with patient confidentiality serving as a major issue.
Retiring Veteran Makes 1 Last Push to See More States Encourage Use of VA Benefits Instead of Medicaid
November 8th 2019

Retiring Veteran Makes 1 Last Push to See More States Encourage Use of VA Benefits Instead of Medicaid

Allison Inserro
States can reduce Medicaid spending if the beneficiaries are also veterans, explains a veteran who started outreach in Washington state, which has since saved over $100 million since 2002.
Parkinson Disease Shown to Induce Immune Imbalance in the Blood, Indicating Possible Benefit of Immune Modulation
November 5th 2019

Parkinson Disease Shown to Induce Immune Imbalance in the Blood, Indicating Possible Benefit of Immune Modulation

Matthew Gavidia
Researchers uncovered that patients with Parkinson disease could benefit from immune modulation as an alternative treatment, due to the condition’s influence on immune imbalance, according to study findings.
Study Finds PKG Movement Recording System Effective for Routine Clinical Care of Parkinson
November 2nd 2019

Study Finds PKG Movement Recording System Effective for Routine Clinical Care of Parkinson

Alison Rodriguez
The Personal KinetiGraph (PKG) Movement Recording System may be effective for routine clinical care of patients with Parkinson disease (PD), according to a recent study.
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