Parkinson Disease

The AJMC® Parkinson Disease compendium is a comprehensive resource for clinical news and expert insights for progressive nervous system disorder, which affects movement and often includes tremors.

Latest News

FDA | Image credit: Postmodern Studio
Adaptive Deep Brain Stimulation Technology Receives FDA Approval for Parkinson Disease

February 26th 2025

The FDA approves BrainSense Adaptive deep brain stimulation and electrode identifier technology for the treatment of Parkinson disease.

Air Pollution Linked to PD, With Mississippi-Ohio River Valley Region Most Affected
Air Pollution Linked to PD, With Some Parts of US More Affected Than Others

February 24th 2023

PD Worsens QOL, Increases Depression in Men More Than Women in the Southeast
PD Worsens QOL, Increases Depression in Men More Than Women in the Southeast

February 17th 2023

Image of a diverse group of patients
Certain Patient Groups Continue to Be Underrepresented in PD Studies in the Netherlands

February 4th 2023

graphic of a brain
Creating a Metric to Determine Social Functioning in Parkinson Disease

February 1st 2023

More News

Challenges, Advice for Caregivers of Patients With Parkinson Disease Experiencing Psychosis
February 26th 2021

Challenges, Advice for Caregivers of Patients With Parkinson Disease Experiencing Psychosis

Matthew Gavidia
Among caregivers of patients with Parkinson disease experiencing psychosis, only 11% learned about the symptom from a physician, with communication challenges attributed to having to prioritize other issues in a limited appointment time.
Assessing Impact of Levodopa Responsiveness on DBS Efficacy in Parkinson Disease
February 23rd 2021

Assessing Impact of Levodopa Responsiveness on DBS Efficacy in Parkinson Disease

Matthew Gavidia
Patients with levodopa-responsive and levodopa-resistant tremors exhibit differing preferences on the type of deep brain stimulation administered to control motor function in Parkinson disease.
Eye Test May Predict Parkinson-Related Cognitive Decline 18 Months Before Onset
February 20th 2021

Eye Test May Predict Parkinson-Related Cognitive Decline 18 Months Before Onset

Matthew Gavidia
Visual dysfunction among patients with Parkinson disease was associated with worse cognitive performance after 18 months and a higher risk of developing mild cognitive impairment compared with those with normal vision.
Gut Fungi Not Found to Be Associated With Parkinson Disease
February 12th 2021

Gut Fungi Not Found to Be Associated With Parkinson Disease

Matthew Gavidia
Fungi within the gut microbiome were not found to be a contributing factor to the initiation and progression of Parkinson disease, contrary to prior findings.
Apple Watch Effective in Monitoring Symptoms of Parkinson Disease
February 8th 2021

Apple Watch Effective in Monitoring Symptoms of Parkinson Disease

Matthew Gavidia
An Apple Watch designed to remotely monitor fluctuations of resting tremor and dyskinesia in persons with Parkinson disease was shown to match in-clinic evaluations of these symptoms and capture symptom changes in response to treatment for 94% of participants.
Prostate Drugs Linked With Lower Risk of Developing Parkinson Disease
February 2nd 2021

Prostate Drugs Linked With Lower Risk of Developing Parkinson Disease

Matthew Gavidia
Use of drugs commonly used to treat enlarged prostate was associated with a reduced risk of developing Parkinson disease in men.
Cannabis
January 28th 2021

Cannabis Shown to Relieve Parkinson Disease Symptoms

Skylar Jeremias
A recent survey found that patients experienced relief of certain motor and nonmotor symptoms of Parkinson disease from using cannabis.
Changes in Blood Pressure, Cholesterol Levels May Predate Motor Symptoms in Parkinson Disease
January 26th 2021

Changes in Blood Pressure, Cholesterol Levels May Predate Motor Symptoms in Parkinson Disease

Matthew Gavidia
Changes in blood pressure, percentage of red blood cells, and serum cholesterol levels were found to occur in patients with Parkinson disease before the onset of motor symptoms, suggesting potential biomarkers for early diagnosis and treatment.
Colorful healthy foods
January 19th 2021

Study Finds That Diet May Delay Onset of Parkinson Disease

Skylar Jeremias
A study on the effects of Mediterranean diets on Parkinson disease found a strong correlation between food intake and disease onset, while also suggesting a possible link between sex and diet results.
Focused Ultrasound Shown to Improve Motor Symptoms in Parkinson Disease
January 15th 2021

Focused Ultrasound Shown to Improve Motor Symptoms in Parkinson Disease

Matthew Gavidia
Focused ultrasound subthalamotomy was shown to improve motor features among patients with Parkinson disease who present with asymmetric symptom severity.
Brain imaging
January 11th 2021

Defective Levodopa Metabolism Linked to Waning Efficacy, Severe Adverse Effects

Matthew Gavidia
Defective metabolism of levodopa in the brain was associated with a decline in the drug's efficacy over time and the adverse effect of dyskinesia among patients with Parkinson disease.
Study Explores Development, Association of Constipation in PD With Other Symptoms
January 9th 2021

Study Explores Development, Association of Constipation in PD With Other Symptoms

Matthew Gavidia
A recent study explored how patients with Parkinson disease who suffer from constipation are more likely to have other nonmotor symptoms than patients without constipation.
How Mutations in the Parkin Gene Affect Quality of Life in Patients With Parkinson Disease
January 4th 2021

How Mutations in the Parkin Gene Affect Quality of Life in Patients With Parkinson Disease

Matthew Gavidia
Patients with newly diagnosed Parkinson disease (PD) who carried mutations in the Parkin gene were found to exhibit worse quality of life, longer disease duration, and an earlier age at disease onset than those with PD who did not carry the mutation.
Top 5 Most-Read Parkinson Disease Articles of 2020
December 31st 2020

Top 5 Most-Read Parkinson Disease Articles of 2020

Matthew Gavidia
The top 5 most-read Parkinson disease stories of 2020 on AJMC.com included the latest insights on treatments such as spinal cord stimulation and the role of dietary management, as well as implications of the coronavirus disease 2019 pandemic.
Tomatoes May Offer Novel Cost-effective Source of Levodopa
December 29th 2020

Tomatoes May Offer Novel Cost-effective Source of Levodopa

Matthew Gavidia
Tomatoes metabolically engineered to be enriched by the antiparkinsonian drug levodopa may provide a novel, cost-effective source of the drug for patients with Parkinson disease.
How Does Presence of Essential Tremor Affect Progression of Parkinson Disease?
December 24th 2020

How Does Presence of Essential Tremor Affect Progression of Parkinson Disease?

Matthew Gavidia
Among patients with Parkinson disease, a positive history of essential tremor was found to be associated with slower progression of motor and nonmotor symptoms, with no impact observed on survival.
Study Finds Patients With Parkinson Disease at Greater Risk of Death by Suicide
December 21st 2020

Study Finds Patients With Parkinson Disease at Greater Risk of Death by Suicide

Matthew Gavidia
Patients with Parkinson disease were shown to be at greater risk of suicide than matched participants in the general population, according to study findings published last week.
Pandemic-Related Social Isolation Linked With Worsening Symptom Severity, Quality of Life in Parkinson Disease
December 19th 2020

Pandemic-Related Social Isolation Linked With Worsening Symptom Severity, Quality of Life in Parkinson Disease

Matthew Gavidia
Amid the coronavirus disease 2019 pandemic, patients with Parkinson disease reporting feelings of loneliness were found to experience greater severity of symptoms.
Email being sent
December 17th 2020

What We’re Reading: Eli Lilly to Buy Prevail Therapeutics; Extra Doses of Pfizer Vaccine; Breast Cancer Drug Approved

AJMC Staff
Eli Lilly & Co is set to acquire Prevail Therapeutics Inc for almost $1 billion; Pfizer’s coronavirus disease 2019 vaccine vials found to contain extra doses; a new treatment has been approved for patients with advanced breast cancer.
Review Outlines Dermatologic Implications in Parkinson Disease
December 10th 2020

Review Outlines Dermatologic Implications in Parkinson Disease

Matthew Gavidia
Researchers review the association between Parkinson disease and dermatologic disorders, as well as implications that this link may have on the pathophysiological mechanisms underlying Parkinson disease.
How Has Neurological Telemedicine Fared Amid COVID-19?
December 8th 2020

How Has Neurological Telemedicine Fared Amid COVID-19?

Matthew Gavidia
The effectiveness of telemedicine services among patients with neurological conditions was spotlighted amid the coronavirus disease 2019 (COVID-19) pandemic, particularly how telephone and video consultations have fared in temporarily replacing face-to-face consultations.
Technological Innovations, Challenges to Integration in Parkinson Disease Management
December 5th 2020

Technological Innovations, Challenges to Integration in Parkinson Disease Management

Matthew Gavidia
Researchers discuss the latest advances in technology-enabled care under development for Parkinson disease, as well as potential challenges to achieve full integration.
What Can Alleviate Levodopa-Induced Dyskinesia in Parkinson Disease?
November 27th 2020

What Can Alleviate Levodopa-Induced Dyskinesia in Parkinson Disease?

Matthew Gavidia
Low-frequency transcranial stimulation of the pre-supplementary motor area was found to delay the onset and reduce severity of levodopa-induced dyskinesia in patients with Parkinson disease.
How an Eye Exam May Improve Early Diagnosis of Parkinson Disease
November 23rd 2020

How an Eye Exam May Improve Early Diagnosis of Parkinson Disease

Matthew Gavidia
An eye exam paired with artificial intelligence machine learning technology may provide a novel approach to diagnose Parkinson disease in early stages.
Conceptual graphic technology and medicine
November 16th 2020

Machine Learning Approach May Offer Future Diagnostic Advances in Parkinson Disease

Matthew Gavidia
A machine learning approach that works to identify mitochondrial impairments, a potential mechanism underlying the pathogenesis of Parkinson disease (PD), accurately distinguished between patients with PD and healthy controls.
How Tremor Affects Learning Abilities in Patients With Parkinson Disease
November 13th 2020

How Tremor Affects Learning Abilities in Patients With Parkinson Disease

Matthew Gavidia
Patients with Parkinson disease (PD) who do not experience tremor were found to show improvements in reward learning after taking dopaminergic medication, while those with PD and tremor exhibited no benefit in reinforcement learning.
Busy doctor
November 6th 2020

How Socioeconomic Status Influences Mortality Risk in Patients With Parkinson Disease

Matthew Gavidia
Individual-level low socioeconomic status (SES) was found to be significantly associated with increased mortality in Korean patients with Parkinson disease, whereas regional-level SES was not.
A Review of Stem Cell–Based Therapies for Parkinson Disease
November 3rd 2020

A Review of Stem Cell–Based Therapies for Parkinson Disease

Matthew Gavidia
Researchers discuss the development and potential of stem cell–based therapies in the treatment of Parkinson disease.
Skin Samples May Improve Earlier Diagnosis of Parkinson Disease
October 27th 2020

Skin Samples May Improve Earlier Diagnosis of Parkinson Disease

Matthew Gavidia
A skin test to detect clumping of alpha-synuclein, an abnormal protein suggested to have a central role in the pathogenesis of Parkinson disease, may assist in improving earlier detection of the condition, according to study findings.
Air Pollution Tied to Higher Hospitalization Risk for PD, Other Neurological Disorders
October 20th 2020

Air Pollution Tied to Higher Hospitalization Risk for PD, Other Neurological Disorders

Matthew Gavidia
Air pollution was found to be significantly associated with an increased risk of hospital admissions for several neurological disorders, including Parkinson disease, Alzheimer disease, and other dementias.
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