Treatment Adherence and Cost Considerations Surrounding Various Routes of PNH Treatment Administration

EP: 1.PNH Overview and Pathophysiology

EP: 2.Intravascular and Extravascular Hemolysis MoA in PNH

EP: 3.Utilizing Health Information Technology to Bridge Gaps in PNH Treatment Programming

EP: 4.Key Treatment Considerations for Patients Diagnosed With PNH

EP: 5.Complement System Role in PNH Treatment Approach

EP: 6.Eculizumab Impact on PNH Treatment Landscape and Unmet Needs in PNH Management

EP: 7.Efficacy End Points For PNH Treatment

EP: 8.Efficacy and Safety Trials Results of Complement Inhibitors

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EP: 9.Treatment Adherence and Cost Considerations Surrounding Various Routes of PNH Treatment Administration

EP: 10.Investigational Therapies Paving New PNH Treatment Pathways

Video content above is prompted by the following:

• In addition to mechanism of action, what role does route of administration play in terms of treatment selection? Please discuss your considerations for different modes of administration in terms of patient adherence and cost.
• What factors guide your decision-making process when initiating treatment for newly diagnosed patients versus adjusting or modifications for those already receiving complement inhibitor therapy?
• What factors prompt you to initiate discussions with patients about switching treatments?