Treating PNH: Understanding Complement Inhibitors, Modes of Administration, and Coordinated Patient Care Needs

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In this AJMC peer exchange program, Dr. Ryan Haumschild and a panel of experts, including Dr. Jamie Koprivnikar, Dr. Brian Mulherin, and Dr. David Dingli, discuss Paroxysmal Nocturnal Hemoglobinuria (PNH), focusing on its pathophysiology, complement inhibitors, treatment strategies, and the challenges of managing this rare, life-threatening disorder.

Episodes

PNH Overview and Pathophysiology

June 4th 2024EP. 1: PNH Overview and Pathophysiology

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Dr. Haumschild drives a discussion providing an overview of PNH and pathology of the disease.

Intravascular and Extravascular Hemolysis MoA in PNH

June 4th 2024EP. 2: Intravascular and Extravascular Hemolysis MoA in PNH

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Medical experts illustrate the nature of hemolysis in PNH and characteristics unique to the disease state.

Utilizing Health Information Technology to Bridge Gaps in PNH Treatment Programming

June 11th 2024EP. 3: Utilizing Health Information Technology to Bridge Gaps in PNH Treatment Programming

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Key opinion leaders navigate barriers to optimal care for patients receiving treatment for PNH.

Key Treatment Considerations for Patients Diagnosed With PNH

June 11th 2024EP. 4: Key Treatment Considerations for Patients Diagnosed With PNH

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Dr Haumschild drives a discussion surrounding impactful PNH treatment strategies.

Complement System Role in PNH Treatment Approach

June 19th 2024EP. 5: Complement System Role in PNH Treatment Approach

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Dr Haumschild continues leading a discussion surrounding management of PNH, emphasizing the impact of complement inhibitors.

Eculizumab Impact on PNH Treatment Landscape and Unmet Needs in PNH Management

June 19th 2024EP. 6: Eculizumab Impact on PNH Treatment Landscape and Unmet Needs in PNH Management

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Medical experts highlight unmet needs in the PNH treatment landscape and considerations for utilizing eculizumab.

Efficacy End Points For PNH Treatment

June 26th 2024EP. 7: Efficacy End Points For PNH Treatment

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Dr Haumschild continues leading an expert discussion surrounding key strategies and pain points in PNH treatment.

Efficacy and Safety Trials Results of Complement Inhibitors

June 26th 2024EP. 8: Efficacy and Safety Trials Results of Complement Inhibitors

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Expert panelists evaluate results regarding complement inhibitor trials for utilization in PNH management.

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