Efficacy End Points For PNH Treatment

EP: 1.PNH Overview and Pathophysiology

EP: 2.Intravascular and Extravascular Hemolysis MoA in PNH

EP: 3.Utilizing Health Information Technology to Bridge Gaps in PNH Treatment Programming

EP: 4.Key Treatment Considerations for Patients Diagnosed With PNH

EP: 5.Complement System Role in PNH Treatment Approach

EP: 6.Eculizumab Impact on PNH Treatment Landscape and Unmet Needs in PNH Management

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EP: 7.Efficacy End Points For PNH Treatment

EP: 8.Efficacy and Safety Trials Results of Complement Inhibitors

Video content above is prompted by the following:

• Please describe the significance of the different efficacy end points explored for paroxysmal nocturnal hemoglobinuria treatments (eg, lactate dehydrogenase levels, hemoglobin concentrations, absolute reticulocyte count (ARC) levels, transfusion avoidance, Functional Assessment of Chronic Illness Therapy–Fatigue).