Opinion
Video
Imaging and Risks in Desmoid Tumors
Experts discuss advancements in imaging techniques and risk factors associated with desmoid tumors, emphasizing the importance of accurate evaluation and management decisions.
This is a video synopsis/summary of a Peer Exchange involving Ryan Haumschild, PharmD, MS, MBA; Tony Phillip, MD; Mrinal Gounder, MD; Ravin Ratan, MD, MEd; and Derek Van Amerongen, MD, MS.
Ratan emphasizes the crucial role of obtaining a tissue diagnosis before intervening or treating desmoid tumors, highlighting the significance of advancements in imaging and biopsy techniques. Phillip underscores that most desmoid cases are sporadic, with only approximately 15% associated with certain mutations such as that of the APC gene, often linked to Gardner syndrome. Gounder cautions against simplifying associations between estrogen-related factors and desmoid tumors, stressing the complexity of cytokines and immune changes in the development of these tumors. The speakers, including Haumschild, discuss risk factors, with Ratan adding that trauma from surgeries may contribute to desmoid development in patients with APC mutations. The conversation emphasizes evolving imaging techniques, risk factor awareness, and the complexity of understanding desmoid tumor causation. Ongoing research, multidisciplinary collaboration, and patient education are key components in navigating the evaluation and management of desmoid tumors effectively.
Video synopsis is AI generated and reviewed by AJMC® editorial staff.
