Evaluating Treatment Outcomes in Dry Eye Disease

EP: 1.Overview of Dry Eye Disease (DED) Causes and Treatments

EP: 2.Adverse Events & Existing Treatment Options for Dry Eye Disease

EP: 3.Navigating Different Subtypes of Dry Eye Disease

EP: 4.Assessing Efficacy of Treatment Through Patient-Reported Outcomes

EP: 5.Updating Formularies: Considerations for Dry Eye Disease

EP: 6.Assessing the Economic Burden of Under Diagnosed Dry Eye Disease

EP: 7.Identifying Key Socioeconomic Burdens Associated with Dry Eye Disease

EP: 8.Resource Allocation in the Treatment of Dry Eye Disease

EP: 9.Quality of Life & Patient Reported Outcomes in Dry Eye Disease

EP: 10.Annual Health Care Costs of Managing Dry Eye Disease

EP: 11.Novel Treatments Targeting Symptoms & Causes of Dry Eye Disease

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EP: 12.Evaluating Treatment Outcomes in Dry Eye Disease

EP: 13.Evaluating Economic Impact of Emerging Therapies for Dry Eye Disease

EP: 14.Concluding Thoughts on the Treatment of Dry Eye Disease

This is a video synopsis/summary of a Stakeholder Summit involving:

Ryan Haumschild, PharmD, MS, MBA; Jai G. Parekh, MD, MBA; and Alexander Kabiri, OD.

Haumschild asks Parekh to compare recently approved therapies like perfluorohexyloctane and varenicline nasal spray to traditional dry eye disease (DED) treatments. Parekh states the medications expand options to precisely match specific DED subtypes and avoid overtreatment. Perfluorohexyloctane addresses evaporative DED, allowing some patients to replace or reduce anti-inflammatory therapy. The nasal spray suits those unable to use drops. He reiterates tailored combinations for precision medicine, noting most patients should not require all available therapies.

Kabiri discusses the disease spectrum, with compromised corneas at one end requiring specialized treatments to restore ocular surface integrity. However, solely targeting downstream inflammation without replacing absent meibomian gland function has limitations. Adding perfluorohexyloctane addresses this underlying deficiency to prevent progression.

Haumschild subsequently asks which patients benefit most from emerging therapies. Kabiri reviews how clinicians identify aqueous-deficient DED with thin tears vs evaporative DED with poor meibomian gland expression. Patients complaining of watery eyes is suggestive of adequate aqueous, but tear film instability may signal underlying meibomian gland dysfunction. Hence, emerging treatments like perfluorohexyloctane, varenicline, and punctal plugs allow the targeting of specific deficiencies.

Video synopsis is AI-generated and reviewed by AJMCÒ editorial staff.