Overview of Dry Eye Disease (DED) Causes and Treatments

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EP: 1.Overview of Dry Eye Disease (DED) Causes and Treatments

EP: 2.Adverse Events & Existing Treatment Options for Dry Eye Disease

EP: 3.Navigating Different Subtypes of Dry Eye Disease

EP: 4.Assessing Efficacy of Treatment Through Patient-Reported Outcomes

EP: 5.Updating Formularies: Considerations for Dry Eye Disease

EP: 6.Assessing the Economic Burden of Under Diagnosed Dry Eye Disease

EP: 7.Identifying Key Socioeconomic Burdens Associated with Dry Eye Disease

EP: 8.Resource Allocation in the Treatment of Dry Eye Disease

EP: 9.Quality of Life & Patient Reported Outcomes in Dry Eye Disease

EP: 10.Annual Health Care Costs of Managing Dry Eye Disease

EP: 11.Novel Treatments Targeting Symptoms & Causes of Dry Eye Disease

EP: 12.Evaluating Treatment Outcomes in Dry Eye Disease

EP: 13.Evaluating Economic Impact of Emerging Therapies for Dry Eye Disease

EP: 14.Concluding Thoughts on the Treatment of Dry Eye Disease

This is a video synopsis/summary of a Stakeholder Summit involving:

Ryan Haumschild, PharmD, MS, MBA; Jai G. Parekh, MD, MBA; and Alexander Kabiri, OD.

Kabiri provides an overview of the main dry eye disease (DED) subtypes: evaporative DED due to meibomian gland dysfunction, aqueous-deficient DED with insufficient aqueous volume, and mixed DED with overlap between the two. He notes most DED involves an evaporative component.

Parekh discusses traditional DED treatments like over-the-counter artificial tears, immunomodulators, and some steroids. Many patients try over-the-counter options before seeing an eye care professional. Recent issues with unbranded artificial tears have further demonstrated the need for branded options as a first line. However, immunomodulators mainly address inflammation, not the evaporative component that underlies most DED. Previous lack of treatments for evaporative DED represents an unmet need. Parekh reports average prescription duration of only 6 to 8 months due to issues like nonresponse, adverse effects, noncompliance, and cost. Finally, Parekh notes emerging focus on meibomian gland disease, a main cause of evaporative DED, with new pharmacotherapies in 2023 offering an opportunity to better address this significant component of DED.

Video synopsis is AI-generated and reviewed by AJMCÒ editorial staff.