The AJMC® clinical page includes all the published content across AJMC.com, The American Journal of Managed Care® and Evidence-Based Oncology™ on a variety of specialties, including dermatology, cardiology, oncology, and rheumatology.
December 26th 2024
The top 5 most-read chronic obstructive pulmonary disease (COPD) articles of 2024 covered topics such as inhaled medication risks, gabapentinoid use, and the link between high white blood cell counts and exacerbations.
Dr Erin Gillaspie Explains How to Discover Best Treatments for Patients With Lung Cancer
September 20th 2023Erin Gillaspie, MD, MPH, FACS, a faculty member of Vanderbilt University Medical Center’s Department of Thoracic Surgery, explained what testing needs to be done to identify the best treatment for patients with lung cancer.
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Adalimumab Plus Surgery Delivers Better Outcomes Than Adalimumab Alone for HS
September 19th 2023Adalimumab in conjunction with surgery demonstrated more clinical effectiveness and improved quality of life in patients with hidradenitis suppurativa (HS) compared with outcomes in those treated with adalimumab alone.
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Relative Benefit in Survival, Reduction in TE/MAVE Risk With Eculizumab for Patients With PNH
September 19th 2023When patients with paroxysmal nocturnal hemoglobinuria (PNH) received eculizumab, survival rates increased and thromboembolic events/major adverse vascular events (TE/MAVE) decreased.
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Predicting Hospitalizations for Patients With Chronic Kidney Disease
The authors developed an algorithm that uses medical claims to identify patients with chronic kidney disease who are at greatest risk of being hospitalized within 90 days.
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Dr Milind Desai on VALOR-HCM: Primary and Secondary Effects Are Sustained While on Mavacamten
September 16th 2023Secondary effects not only improved past 16 weeks, but showed a sustained improvement at week 56 of mavacamten, said Milind Desai, MD, MBA, director of the Hypertrophic Cardiomyopathy Center and vice chair of education at the Heart, Vascular & Thoracic Institute, Cleveland Clinic.
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Diet and Exercise Intervention Associated With Better pCR in TNBC or HR+, HER2– BC
September 16th 2023Despite seeming to elicit more pathological complete responses (pCRs) in patients with hormone receptor–positive (HR+), HER2-negative triple-negative breast cancer (BC) receiving neoadjuvant chemotherapy, diet and exercise did not affect relative dose intensity.
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Switching Back to Originator From Biosimilar Infliximab Results in Higher Discontinue Rates
September 16th 2023One-fourth of patients who switched to an infliximab biosimilar retransitioned back to the originator, but they were more likely to subsequently discontinue treatment due to an unwanted response after switching back.
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Novel PET-Based Radiomics Signature Predicts CAR T Efficacy in DLBCL
September 15th 2023A PET-based radiomics signature was able to predict the efficacy of chimeric antigen receptor (CAR) T-cell therapy and performed better than conventional PET biomarkers in patients with relapsed or refractory (R/R) diffuse large B-cell lymphoma (DLBCL).
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Higher Smoking Abstinence Rate Found Among e-Cigarette Users During Late Pregnancy
September 15th 2023Researchers found that individuals who used e-cigarettes had a higher smoking abstinence rate in late pregnancy than those who used nicotine reduction therapy, especially for those who began using e-cigarettes before pregnancy.
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Dr Zachary Cox: Early Dapagliflozin Modestly Improves Diuresis, Decongestion for Patients With ADHF
September 14th 2023Despite not reaching statistical significance, findings from DICTATE-AHF show early dapagliflozin improved decongestion and led to earlier hospital discharge for patients with acute decompensated heart failure, explained Zachary Cox, PharmD, professor at Lipscomb University College of Pharmacy.
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Memory Consolidation in Epilepsy Enhanced During Sleep With Deep Brain Stimulation
September 14th 2023Researchers developed a novel “closed-loop” system that delivered electrical pulses in a brain region to synchronize brain activity recorded from another region in the brain to improve memory.
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