Clinical

A pair of abstracts presented during this year’s 64th American Society of Hematology Annual Meeting and Exposition explored barriers to treatment for sickle cell disease (SCD).

Guillermo Garcia-Manero, MD, highlights the ASCERTAIN trial in his opening thoughts surrounding MDS in this ASH 2022 post-conference perspective.

Carlos M. De Castro, MD, highlights the phase III Apply-PNH study presented at ASH 2022.

Patient education is critical for self-monitoring of COPD disease progression.

An expert panel discusses appropriate transitions and adjustments to COPD treatment approaches.

Medical experts share considerations for early intervention in patients with diagnoses of diabetes.

Medical experts navigate risk factors associated with diabetes.

Ryan Haumschild, PharmD, MS, MBA, leads a panel in a conversation reviewing the MAIA study.

Key opinion leaders open a discussion surrounding the current treatment landscape of multiple myeloma (MM).

In heart failure this year, value-based care, left ventricular ejection fraction, and disease prevention were among the most popular topics discussed.

A pair of abstracts presented at this year’s 64th American Society of Hematology Annual Meeting and Exposition bear out the significant transfusion-free rate at 3 years following beti-cell administration and marked improvements in patient-reported outcomes, including the ability to work and be physically active.

A retrospective study found roxadustat to be more effective in improving hemoglobin levels in patients who had with chronic kidney disease (CKD) compared with recombinant human erythropoietin.

Overall survival for patients with combined hepatocellular-cholangiocarcinoma is poor, but those who received adjuvant transarterial chemoembolization (TACE) after surgery had a prolonged recurrence-free survival (RFS).

This new study, which followed patients up to 6 months after functional endoscopic sinus surgery, evaluated results using objective and subjective measures.

Although rare, stiff person syndrome spectrum disorders can significantly affect patient quality of life, and current knowledge gaps warrant further research.

In her final thoughts regarding gastroesophageal cancer, Laura Bobolts, PharmD, BCOP, overviews patient support services and programs.

Laura Bobolts, PharmD, BCOP, shares her perspective surrounding cost-effective analyses surrounding GI and esophageal cancers.

Laura Bobolts, PharmD, BCOP, discusses GI and esophageal cancer treatment pathway decisions.

Expert panelists consider factors affecting treatment adherence for patients with MDD.

Drs Weaver and Chitre illustrate a population health approach strategy for MDD.

A recent meta-analysis found ASXL1 mutations to be independent risk factors for worse overall survival and transformation to acute myeloid leukemia in patients with myelodysplastic syndromes (MDS), as well as worse overall survival in acute myeloid leukemia (AML).

M. Hossein Kazemi, MD, medical oncologist and hematologist, Astera Cancer Care, identifies key tools in de-escalating treatment for patients with multiple myeloma.

The top news out of the annual meeting of the American Society of Clinical Oncology (ASCO) highlighted findings in gliobastoma, HER2-low breast cancer, and Hodgkin lymphoma.

The study also showed daily energy intake was inversely correlated with estimated glucose disposal rate (eGDR), a marker for insulin resistance (IR).

Implantable cardioverter defibrillators (ICDs) were found to have a beneficial effect on mortality in patients with chronic kidney disease (CKD).

Jorge Larranaga, MD, discusses the AURORA 2 study and its emphasis on voclosporin.

Belimumab and voclosporin are highlighted as key contributors to the lupus nephritis treatment landscape.

Although the skin condition is common in systemic lupus erythematosus (SLE), it usually is not the initial manifestation.

Jaime Murillo, MD, discusses the impact of diabetes on cardiovascular disease.