April 12th 2025
Data from a meta-analysis of 8 observational studies accounting for more than 26 million people across the globe were evaluated in a new review.
Analysis Identifies Gut Microbiota Affecting Risk of MG
February 29th 2024The Mendelian randomization–based analysis, which examines how variation in genes have a causal effect of an exposure on certain outcomes, identified 12 gut microbiota associated with either an increased of or protective effect against MG.
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Children With SCD Exhibit Distinctive Palatal Rugae Patterns
February 29th 2024A cross-sectional study analyzing morphological and dimensional features of palatal rugae patters revealed that distinct anomalies exist in children with sickle cell disease (SCD) compared with children without.
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What Are the Steps to Quality Improvement in Cancer Care?
February 29th 2024Quality Improvement (QI) projects require a series of distinct steps and timely data collection that will allow clinics to see if changes are yielding results, a consultant told attendees at a preconference workshop at ACCC.
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Coverage Expansion, Other Economic Policies May Yield Positive Impact on Hypertension Management
February 28th 2024Researchers of the review are underscoring the potential for economic policies to improve the management of hypertension for the millions of people throughout the United States with the condition who are at risk for cardiovascular disease.
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Mental Health Forum 2024: How the Mental Health Parity Act Affects Employers and Providers
February 28th 2024In a recent presentation featured at the Midwest Business Group on Health's Mental Health Forum, an expert shed light on the evolving landscape shaped by the Mental Health Parity and Addiction Treatment Act.
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Primary Care Delivery Is in Urgent Need of Innovation
February 28th 2024At an Institute for Value-Based Medicine® event cohosted by The American Journal of Managed Care® and Optum, speakers emphasized that innovation is urgently needed in primary care delivery to address the broken US health care system.
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ACTRIMS 2024 Seeks to Explore and Break Barriers in MS
February 26th 2024The Americas Committee for Treatment and Research in Multiple Sclerosis (ACTRIMS) will host its ninth annual meeting in West Palm Beach, Florida, from February 29 to March 2, 2024, to address a plethora of barriers faced by patients and clinicians managing multiple sclerosis (MS).
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The Promise of Frexalimab in MS Treatment: Part 1
February 26th 2024Patrick Vermersch, MD, PhD, joined The American Journal of Managed Care® for an interview on promising data from a phase 2 clinical trial on frexalimab in the treatment of multiple sclerosis (MS) and associated neurodegeneration.
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Health Equity and Access Weekly Roundup: February 24, 2024
February 24th 2024This week's news from the Center on Health Equity and Access discusses racial disparities in prostate cancer outcomes, the impact of access to cancer care on racial gaps in CLL/SLL outcomes, the effects of 340B programs on drug pricing and health care disparities, the role of mental illness in maternal mortality rates, and racial bias and diagnosis disparities in bipolar disorder.
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Camilla Levister on the Nuances of Designing a Pregnancy-Specific Artificial Pancreas System for T1D
February 24th 2024Camilla Levister, MS, ANP-C, CDCES, a nurse practitioner at the Icahn School of Medicine at Mount Sinai Hospital in New York, gives insight into the nuances of testing closed-loop insulin delivery systems for pregnant women.
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Kathy Oubre on Strategies to Mitigate Challenges When Adopting New Payment Models
February 23rd 2024While adopting new payment models can come with challenges, there are strategies that can help oncology practices optimize their approaches, said Kathy Oubre, MS, CEO of Pontchartrain Cancer Center.
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There Is No Interaction Between BMI and SGLT2 Inhibitor Efficacy in HF, Review Finds
February 23rd 2024Among patients with heart failure (HF), those taking dapaglifozin or empaglifozin had a 30% odds reduction in HF hospitalization, 14% odds reduction in cardiovascular mortality, and a 10% odds reduction in all-cause mortality compared with patients taking placebo.
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Unlocking T1D Risk: Environmental and Genetic Factors Investigated
February 22nd 2024Outside of genetics, which has a well-documented link to the risk of type 1 diabetes (T1D), investigators detail available research spanning a variety of factors, including viral infections, pesticide exposure, and the gut microbiome.
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Venetoclax Plus HMA Therapy Shows Encouraging Results in Higher-Risk MDS/CMML
February 22nd 2024Results of a phase 1/2 trial show encouraging outcomes for patients with higher-risk myelodysplastic syndromes (MDS) and chronic myelomonocytic leukemia (CMML) treated with the fully oral regimen of venetoclax and decitabine plus cedazuridine.
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Patients With Early vs Advanced HCC Show Distinct Gut Microbiota Alterations
February 21st 2024Patients with early-stage hepatocellular carcinoma (HCC) and those with advanced-stage disease exhibited distinct gut microbiota diversity and alterations, with future studies warranted to investigate the mechanisms underlying the interactions between gut microbiota and HCC progression.
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Dr Jun Gong: Improved Access Closes the Gaps Between Black, White Men With Prostate Cancer
February 18th 2024Despite socioeconomic and biological differences that contribute to disparities between Black men and White men with prostate cancer, improved access has been shown to reduce the gaps, explained Jun Gong, MD, of Cedars Sinai.
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Experimental RNA Therapy Significantly Reduces Blood Pressure up to 6 Months, Study Says
February 18th 2024Researchers said these findings confirm that zilebesiran can significantly reduce serum angiotensinogen levels, leading to sustained reductions in blood pressure over a 24-hour period, even 6 months post-treatment, though more research is needed for longer-term use.
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Hospitalized Children With Diabetes May Be Able to Continue Safe Use of Home Pumps, Suggest Findings
February 17th 2024Using home insulin pumps when hospitalized was relatively safe compared with hospital-managed pumps and insulin injections among more than 2700 children admitted to a single hospital center.
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Combination Therapies Provide Optimal Hypertensive Control in Patients Taking Ibrutinib
February 17th 2024The retrospective study found patients on Bruton’s tyrosine kinase inhibitors are similar to the general population in the sense that it usually takes at least 2 anti-hypertensive drugs to control blood pressure.
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FDA Grants Accelerated Approval to Lifileucel, First Cellular Therapy for Advanced Melanoma
February 16th 2024Lifileucel was granted approval for the treatment of adults with unresectable or metastatic melanoma that has been previously treated with other therapies, marking the first approval of a tumor-derived cellular therapy in a solid tumor cancer.
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