April 10th 2025
This article appears in the April issue of Evidence-Based Oncology.
Phase 2 Trial Shows Weekly Insulin Injection Outcomes Similar to Daily Injections for T2D
September 22nd 2020In individuals with type 2 diabetes with no previous insulin treatment, once-weekly injections of insulin icodec resulted in glucose-lowering efficacy and a safety profile similar to individuals who took once-daily insulin glargine U100.
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Choosing the Right MS Treatment by Customizing Therapy to the Individual
September 13th 2020With more multiple sclerosis (MS) treatments becoming available, it is now possible to better personalize approaches, explained speakers during a session at MSVirtual 2020: 8th Joint ACTRIMS-ECTRIMS Meeting.
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Real-World Study: Dupilumab for Atopic Dermatitis More Effective Than Clinical Trial Results
September 12th 2020The broadest real-life study of dupilumab in atopic dermatitis (AD) found significant improvements in adults with moderate to severe AD that were even greater than the results reported in clinical trials.
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Study Highlights Prevalence of Comorbid Autoimmune Diseases, T1D in Pediatric Populations
September 9th 2020In recent years, the number of children diagnosed with additional autoimmune diseases accompanying type 1 diabetes (T1D) has increased, according to a study published in Frontiers in Endocrinology.
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Secukinumab Significantly Improves Signs, Symptoms of Nonradiographic Axial Spondyloarthritis
August 18th 2020Secukinumab 150 mg improves signs and symptoms of patients with nonradiographic axial spondyloarthritis, according to results of the PREVENT trial published in Arthritis & Rheumatology.
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Screening for Breast Cancer at Younger Ages Linked to Reduced Mortality
August 14th 2020Screening women aged 40 to 49 years for breast cancer reduced mortality by 25% in the first 10 years compared with waiting until at age 50 years and older, which is the common practice in the United Kingdom.
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How Can the COVID-19 Pandemic Enhance Value-Based Health Care Delivery?
August 12th 2020Given the constraints prevalent post-COVID-19, Dr Mark Fendrick, director of the University of Michigan Center for Value-Based Insurance Design, stresses that it is now more important than ever for the health care industry to prioritize payment reform, value-based benefit design, and novel policy initiatives.
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Dr Ajai Chari Discusses the Importance of Real-World Evidence in Multiple Myeloma
September 11th 2019Real-world outcomes are important because the populations included in clinical trials rarely reflect the populations actually being treated in the clinic, said Ajai Chari, MD, associate professor of medicine, Hematology and Medical Oncology, Mount Sinai Hospital.
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Dr Ginah Nightingale: Challenges of Treating Seniors With Cancer With Combination Therapies
August 25th 2019When seniors with cancer are being treated with combination therapies, providers need to keep in mind more than just the complex regimens they’re administering, said Ginah Nightingale, PharmD, associate professor of pharmacy practice at Jefferson College of Pharmacy.
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Dr Ajai Chari Outlines Disparities and Treatment Patterns in Multiple Myeloma
August 24th 2019Research has shown disparities in multiple myeloma treatment between clinical trials and real-world outcomes, as well as a lot of heterogeneity among treatment patterns by age and region, said Ajai Chari, MD, associate professor of medicine, Hematology and Medical Oncology, Mount Sinai Hospital.
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Ochsner Names 2019 Alton Ochsner Award Relating Smoking and Disease Honorees
August 21st 2019For 34 years, Ochsner Health System has annually recognized scientists who have made major contributions regarding the relationship between smoking and disease along with the development of innovative treatment modalities.
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MDM2 Antagonists Help CDK4/6 Inhibitors Overcome Resistance in Melanoma
August 21st 2019Outside of breast cancer, cyclin-dependent kinases 4 and 6 (CDK4/6) inhibitors have not been as successful as tumors develop resistance. New research shows that a murine double minute (MDM2) antagonist can help CDK4/6 inhibitors overcome resistance, offering a potential second-line treatment option in melanoma.
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Changing Demographics Among Populations Prescribed HCV Treatment, 2013-2017
From 2013 to 2017, the population of US patients prescribed treatment for chronic hepatitis C virus (HCV) changed, becoming predominantly treatment-naïve and having received care in nonacademic centers.
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Understanding Price Growth in the Market for Targeted Oncology Therapies
The prices of targeted oncology therapies have grown substantially, but revenues have not. This is due in part to large declines in per-drug patient counts.
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Beyond Satisfaction Scores: Exploring Emotionally Adverse Patient Experiences
This study explores the causes of emotionally adverse patient experiences in cancer care and presents a taxonomy for analyzing free-text patient data.
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Effect of Changing COPD Triple-Therapy Inhaler Combinations on COPD Symptoms
April 10th 2019Changing patients from an inhaled corticosteroid (ICS)/long-acting β agonist (LABA) inhaler and long-acting muscarinic agonist (LAMA) inhaler to a LAMA/LABA inhaler and a separate ICS inhaler did not appear to affect patient-reported chronic obstructive pulmonary disease (COPD) symptom scores.
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