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Coverage of our peer-reviewed research and news reporting in the health care and mainstream press.

Following safety reports of bleeding events after treatment with upifitamab rilsodotin among patients with platinum-sensitive ovarian cancer, the FDA places a partial clinical hold on enrollment for the UP-NEXT and UPGRADE-A trials.

Multiple risk factors for uncontrolled asthma include racial and ethnic barriers, as well as health insurance status, according to one study.

Researchers noted that despite the promising findings, more novel treatments are needed to overcome the disease’s resistance.

New estimates predict that type 2 diabetes prevalence will more than double in the next 30 years, from 529 million people in 2021 to at least 1.3 billion in 2050.

Shifts in clinical treatment patterns could prompt investigators to revisit the cost-effectiveness question.

Considering the depth and durability of responses with axicabtagene ciloleucel (axi-cel) in large B-cell lymphoma (LBCL), the investigators added that CAR T cells should no longer be seen as a therapy only for heavily pretreated patients, but also as an option for earlier lines of therapy.

The US federal government is finally updating its standards for reporting data on race and ethnicity – and it’s an urgently needed chance to enable a national overview of crucial data on health inequities

A session chaired by ASCO and ESMO leadership included experts on the latest lung and colorectal cancer screening technologies and persistent disparities in screening access and uptake.

Hospitalizations of infants in 4 middle-income countries were associated with respiratory syncytial virus (RSV) during the respiratory illness season.

Data presented at the 2023 European Hematology Association Annual Meeting showed positive outcomes in patients with follicular lymphoma and large B-cell lymphoma, and further evaluation in diffuse large B-cell lymphoma is ongoing.

Andy Blauvelt, MD, MBA, president of Oregon Medical Research Center, discusses challenges many physicians face in getting approved for the most effective drugs to treat patients with atopic dermatitis (AD).

PhRMA files a lawsuit against the Inflation Reduction Act; a CDC advisory panel recommends that older adults receive Pfizer and GSK RSV vaccines; a federal program to improve rural maternal care has missed Black women.

Patients often relapse after discharge from acute care because of long waits for outpatient treatment, lack of specialized therapists, out-of-pocket costs, and inadequate social support.

Higher baseline blood eosinophil count was linked to improvement in asthma exacerbations and overall better outcomes seen with biologic therapies.

Officials note it could slow acquisition of physicians’ offices, but hospitals bristle at prospect.

Researchers laid out 6 position statements for the technology in this patient population.

Researchers found that those with both type 2 diabetes and chronic obstructive pulmonary disease (COPD) had lower all-cause and respiratory-cause mortality survival probabilities than those without COPD.

Yesterday’s FDA approvals of a new indication for empagliflozin and combination empagliflozin with metformin hydrochloride for pediatric type 2 diabetes (T2D) provide a new class of oral drugs to treat the condition in children.

Talazoparib in combination with enzalutamide showed a 55% reduction in the risk of disease progression or death for patients with metastatic castration-resistant prostate cancer (mCRPC) with homologous recombination repair (HRR) gene mutations in the phase 3 TALAPRO-2 trial.

White House executives met with opioid overdose reversal drug company representatives Tuesday in an attempt to resolve concerns around the drugs’ costs; a national panel of officials recommends that most adults be screened for depression and anxiety, but not suicide; New York passed a law to protect abortion providers who send abortion pills to states with bans.

In this interview from SLEEP 2023, Andrew McHill, PhD, of Oregon Health and Science University (OHSU), explains the importance of individualizing sleep hygiene recommendations.

Improving access to diabetes technology so that everyone can benefit is a top priority, said David Maahs, MD, PhD, professor of pediatrics at Stanford University and division chief of pediatric endocrinology at Lucile Packard Children’s Hospital.

Initiating targeted therapy for eligible patients with advanced non–small cell lung cancer (NSCLC) was found to improve outcomes, even when patients were started on nontargeted therapy but switched in a timely manner.

Certain sleep difficulties present in the transition from childhood to adolescence might be associated with psychopathology symptoms.

Biosimilars are starting to make a significant impact in overall drug spending, which is what they are designed to do, said Scott Soefje, PharmD, director of pharmacy cancer care at Mayo Clinic.

Higher levels of fractional exhaled nitric oxide (FeNO) were found in patients with eosinophilic esophagitis (EoE) and might be able to provide a measurement of clinical treatment response in a subset of these patients.

Social risk factors, such as patient characteristics and where they live, informed the severity of microbial keratitis in a sample of patients.

Preliminary data suggest the number of meningococcal disease cases among individuals with HIV doubled in 2022, while vaccination rates for the disease remain low.

The burden of respiratory syncytial virus (RSV) and the effect of vaccines could be affected by underestimation of RSV in older adults.