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Investigators say their research could open new avenues of investigation into Chagas disease, the often-neglected tropical disease.

The researchers emphasized the importance of early referral for chimeric antigen receptor (CAR) T-cell treatment, as patients eligible for the treatment are often in very late stages of disease, and mitigating delays in care has the potential to improve response rates by more than 10%.

Barriers to acceptance included privacy concerns and fears about the possibility of misinterpretation of messages.

Those with the infection who underwent treatment exhibited improved outcomes compared with patients without the infection.

Ghassan Abou-Alfa, MD, medical oncologist at Memorial Sloan Kettering Cancer Center, expands on findings that durvalumab plus tremelimumab demonstrated an overall survival benefit at 4 years for certain patients with unresectable hepatocellular carcinoma.

Researchers seeking answers regarding the most beneficial duration of immune checkpoint inhibitor–based therapy for non–small cell lung cancer (NSCLC) found no significant impact of indefinite-duration treatment on patient survival.

Researchers found that treatment for atopic dermatitis could contribute to a higher mutation rate.

Physicians and health care groups have lined up to support the Value in Health Care Act, which could create new incentives to adopt value-based care.

The study adds to a growing amount of literature documenting the impact of psoriasis on mental health.

A study from China suggests calcium and magnesium malnutrition is associated with Crohn's disease inflammation and activity.

After the COVID-19 vaccine was released, disparities in COVID-19 incidence shrunk. However, although efforts were made to increase access to the COVID-19 vaccine in low-income areas, discrepancies in overall vaccination coverage persisted between higher- and lower-income communities.

Echocardiogram and clinical features help researchers identify epilepsy after encephalitis in children.

A study that analyzed pre- and postpandemic respiratory syncytial virus (RSV) seasons found that children and adults followed the same biannual pattern.

Called the TRIO comprehensive, integrated patient data repository (TRIO CIPDR), the unique registry combines clinical data from electronic health records with pharmacy data, including PAH-specific drugs prescribed, as well as the dates prescribed, administered, and refilled.

Intraparty disagreements over mifepristone cause pause in spending bill agreement until August recess ends; Officials urge the FDA to regulate cannabidiol as a dietary supplement; State medical boards tasked with protecting Americans frequently failed to stop doctors for COVID-19 misinformation.

Coverage of our peer-reviewed research and news reporting in the health care and mainstream press.

Evidence shows almost zero risk of sexual transmission when HIV viral loads are less than 1000 copies/mL, which could allow providers to destigmatize HIV and promote antiretroviral therapy adherence.

Congenital thrombotic thrombocytopenic purpura (TTP), an ultra-rare disease, can significantly impact quality of life, but clinicians have previously lacked a disease-specific way to track experiences via patient-reported outcomes (PROs).

Following hospital discharge, patients with multisystem inflammatory syndrome in children (MIS-C) had worse outcomes in areas of neurology, working memory, depression, and quality of life.

Racial minority patients and low socioeconomic status patients tended to face the most barriers.

Fewer patients opt to skip therapy for their multiple myeloma (MM) despite progressive disease than previously thought, a new study suggests.

Initiation of sodium-glucose cotransporter-2 inhibitors (SGLT2is) was associated with a 34% lower rate of recurrent gout flare compared with initiation of dipeptidyl peptidase 4 inhibitors (DPP-4is).

Select lifestyle practices can help to reduce particulate matter (PM) concentrations and exposure in patients with chronic obstructive pulmonary disease (COPD), which can affect clinical outcomes.

A study conducted in Japan found that short-term exposure to statins was not associated with an increased risk of open-angle glaucoma (OAG) in a population with dyslipidemia.

Investigators will submit data from the phase 3 ENHANCE trial evaluating magrolimab plus azacitidine in higher-risk myelodysplastic syndromes for presentation at a future medical meeting.

Democratic House forerunners present legislation to expand drug cost lowering procedures; President Joe Biden presents an advanced cancer research push; a Senate panel advances a pharmacy benefit manager (PBM) reform bill.

Lymphoplasmapheresis (LPE) was also completed with fewer replacements compared with plasma exchange (PE) for myasthenia gravis (MG).

On this episode of Managed Care Cast, we speak with the lead researcher from a study published in the July 2023 issue of The American Journal of Managed Care® on whether social determinants of health is a predictor for identifying high-cost utilizers among those with commercial health insurance.

Highly resourced accountable care organizations (ACOs) were more likely to offer digital health services.

Diffuse large B-cell lymphoma (DLBCL) is the most common non-Hodgkin subtype in individuals living with HIV.