Parkinson Disease

The AJMC® Parkinson Disease compendium is a comprehensive resource for clinical news and expert insights for progressive nervous system disorder, which affects movement and often includes tremors.

Latest News

Air Pollution Linked to PD, With Mississippi-Ohio River Valley Region Most Affected
Air Pollution Linked to PD, With Some Parts of US More Affected Than Others

February 24th 2023

The latest research to look at the links between Parkinson disease and air pollution said the Rocky Mountain region and the Mississippi-Ohio River Valley appeared to be the most affected.

PD Worsens QOL, Increases Depression in Men More Than Women in the Southeast
PD Worsens QOL, Increases Depression in Men More Than Women in the Southeast

February 17th 2023

Image of a diverse group of patients
Certain Patient Groups Continue to Be Underrepresented in PD Studies in the Netherlands

February 4th 2023

graphic of a brain
Creating a Metric to Determine Social Functioning in Parkinson Disease

February 1st 2023

Woman in meditation position
Mindfulness Training May Improve Outcomes for People With Parkinson Disease

January 30th 2023

More News

Sleep Woes, Gastrointestinal Dysfunction Linked With Thalamic Atrophy in Parkinson
November 2nd 2019

Sleep Woes, Gastrointestinal Dysfunction Linked With Thalamic Atrophy in Parkinson

Alison Rodriguez
Greater non-motor symptom burden may be associated with thalamic atrophy in Parkinson disease (PD), suggesting that the thalamus has a significant role in processing sensory information including visceral afferent from the gastrointestinal tract and regulating states of sleep.
Manual Dexterity Test May Offer Clues to Earlier Parkinson Diagnosis
October 26th 2019

Manual Dexterity Test May Offer Clues to Earlier Parkinson Diagnosis

Allison Inserro
Performance on a manual dexterity test can act as an objective behavior marker that can aid in detecting the prodromal stage of patients with Parkinson disease.
Parkinson Disease Affects Quality of Life Among Family Members, Study Finds
October 26th 2019

Parkinson Disease Affects Quality of Life Among Family Members, Study Finds

Alison Rodriguez
Parkinson disease significantly impacts an individual’s quality of life (QoL); however, many spouses and family’s QoL and finances are also affected through increased healthcare and privately borne costs as the condition progresses, according to a recent study.
Study Finds Genetic Markers Linked to Beginning Phase of Parkinson
October 22nd 2019

Study Finds Genetic Markers Linked to Beginning Phase of Parkinson

Alison Rodriguez
Researchers have identified a group of genetic variants related to the starting point of Parkinson disease.
Backward Gait Dynamics More Impaired in Patients With Parkinson
October 19th 2019

Backward Gait Dynamics More Impaired in Patients With Parkinson

Alison Rodriguez
A recent study investigated whether gait parameters were implicated in motor symptoms or the risk of falling, fining that backward gait (BG) dynamics were more impaired in patients with Parkinson's disease.
Patients With Bipolar Disorder More Than 3 Times as Likely to Develop PD
October 18th 2019

Patients With Bipolar Disorder More Than 3 Times as Likely to Develop PD

Allison Inserro
A meta-analysis suggests that patients with bipolar disorder have a much greater risk of developing Parkinson disease (PD).
Higher BMI Appears to Have Protective Effect Against Dementia in Patients With PD
October 11th 2019

Higher BMI Appears to Have Protective Effect Against Dementia in Patients With PD

Allison Inserro
A higher-than-normal body mass index (BMI) at the time of a diagnosis of Parkinson disease (PD) has a protective effect against cognitive decline and the conversion to dementia, a recent study indicated.
Study Finds Pimavanserin May Effectively Treat Parkinson Disease Psychosis
October 5th 2019

Study Finds Pimavanserin May Effectively Treat Parkinson Disease Psychosis

Alison Rodriguez
Pimavanserin may be an effective treatment option for patients with Parkinson disease who develop Parkinson disease psychosis, according to a recent study published by Neuropsychiatric Disease and Treatment.
Top 5 AJMC® Articles of September 2019
September 30th 2019

Top 5 AJMC® Articles of September 2019

Here are the top 5 articles for the month of September.
Visuospatial Abilities May Negatively Impact Theory of Mind in Parkinson, Study Says
September 28th 2019

Visuospatial Abilities May Negatively Impact Theory of Mind in Parkinson, Study Says

Alison Rodriguez
Cognitive status may be affected by the relationship of Parkinson disease (PD) and affective theory of mind through the involvement of visuospatial abilities (VSA), a recent study reported.
Scientists Sharpen Focus Into Genetic Link to Parkinson Inflammation
September 27th 2019

Scientists Sharpen Focus Into Genetic Link to Parkinson Inflammation

AJMC Staff
Researchers studied a particular mutation in a gene linked to Parkinson.
Review Investigates Deep Brain Stimulation Treatment Outcomes in Parkinson Disease
September 21st 2019

Review Investigates Deep Brain Stimulation Treatment Outcomes in Parkinson Disease

Alison Rodriguez
Researchers investigated current evidence linking genetic variation to deep brain stimulation treatment and outcomes in Parkinson disease (PD), finding a promising development where genetic profiling may be important for clinicians to personalize medical and surgical therapy for patients.
Common Prostate Drug May Slow Progression of Parkinson, Researchers Say
September 19th 2019

Common Prostate Drug May Slow Progression of Parkinson, Researchers Say

AJMC Staff
Terazosin, a drug used to treat enlarged prostate, may also be able to slow the progression of Parkinson disease.
Study Investigates Functional Connectivity of Praxis in Parkinson
September 14th 2019

Study Investigates Functional Connectivity of Praxis in Parkinson

Alison Rodriguez
A study investigating the functional connectivity of the praxis network in patients in the early stages of Parkinson’s disease (PD) found that dopaminergic therapy may normalize praxis abilities and related praxis networks during the early stages of the disease by facilitating the propagation of long-term representations of object-related actions to motor execution areas.
At-Home Aerobic Exercise Program Lessens Symptoms in Patients With Parkinson
September 14th 2019

At-Home Aerobic Exercise Program Lessens Symptoms in Patients With Parkinson

Allison Inserro
The research found that aerobic exercise for 30 to 45 minutes for 3 times a week had an effect similar to that of several conventional Parkinson drugs in patients with mild severity.
AJMC® in the Press, September 13, 2019
September 13th 2019

AJMC® in the Press, September 13, 2019

AJMC Staff
Coverage of our peer-reviewed research and news reporting in the healthcare and mainstream press.
Study Examines Orthostatic Hypotension, Association With Dementia in Parkinson Disease
September 6th 2019

Study Examines Orthostatic Hypotension, Association With Dementia in Parkinson Disease

Alison Rodriguez
A recent study investigating orthostatic hypotension (OH)—a common condition among patients with Parkinson disease—found that the causality between OH and dementia may be bidirectional and early diagnosis is important to improve long-term prognosis.
Large European Study Links Soda Consumption to Greater Risk of Mortality, Including From Parkinson
September 3rd 2019

Large European Study Links Soda Consumption to Greater Risk of Mortality, Including From Parkinson

Allison Inserro
A population-based study examining soda consumption in 10 European countries found that soft drinks were linked to a greater risk of death, as well as the chance of dying from Parkinson disease, although that connection needs additional research.
Researchers Explore Convergence Insufficiency, Cognitive Impairment in Parkinsonian Disorders
August 31st 2019

Researchers Explore Convergence Insufficiency, Cognitive Impairment in Parkinsonian Disorders

AJMC Staff
The relationship between cognitive impairment and symptomatic convergence insufficiency in Parkinsonian disorders has not been previously investigated.
Using Wearable Sensors at Home Can Detect Falls Among Patients With Parkinson Disease
August 29th 2019

Using Wearable Sensors at Home Can Detect Falls Among Patients With Parkinson Disease

Christina Mattina
Using a body-worn sensor to detect falls at home is feasible for elderly individuals, including those with Parkinson disease, who have a higher risk of falling, according to new study findings.
Coffee Consumption Linked to Less Severe Tremors in Men With Parkinson
August 22nd 2019

Coffee Consumption Linked to Less Severe Tremors in Men With Parkinson

Christina Mattina
A new study has found a dose-dependent relationship between coffee consumption and reduced severity of tremors in men with Parkinson disease.
Pain Treatment for Patients With Parkinson an Unmet Need
August 20th 2019

Pain Treatment for Patients With Parkinson an Unmet Need

Allison Inserro
Researchers recommended strategies for providers to think about when managing this population.
Researchers Seek to Determine Genetic Variability in Parkinson Progression
August 17th 2019

Researchers Seek to Determine Genetic Variability in Parkinson Progression

AJMC Staff
Researchers said taking genetic variability into account in the future will be helpful not only to understand the course of Parkinson disease but also to minimize heterogeneity in clinical trials.
Estrogen Therapy Suggested to Help Treat Parkinson Symptoms Based on Mouse Model
August 15th 2019

Estrogen Therapy Suggested to Help Treat Parkinson Symptoms Based on Mouse Model

Christina Mattina
Researchers aiming to better understand the role of estrogen in the development of Parkinson disease (PD) and its potential as a treatment found that brain-selective estrogen therapy resulted in motor improvements in male mice with PD-like symptoms.
Survey: Caregivers of Patients With PD Note Nonmotor Symptoms More Often Than Patients
August 10th 2019

Survey: Caregivers of Patients With PD Note Nonmotor Symptoms More Often Than Patients

Allison Inserro
The survey aimed to better understand the perceptions, experiences, and educational needs of patients who have nonmotor symptoms of Parkinson disease as well as their caregivers.
Study Compares Motivation to Participate in Parkinson Disease Genetic Research Across Ethnicities
August 8th 2019

Study Compares Motivation to Participate in Parkinson Disease Genetic Research Across Ethnicities

Christina Mattina
An analysis of patients’ and caregivers’ willingness to participate in genetic studies on Parkinson disease found that although overall levels of motivation were similar in Hispanic and non-Hispanic patients, the reasons behind this interest varied between the groups.
Homebound and Alone: Women With Advanced PD More Likely to Lack Caregiver
August 1st 2019

Homebound and Alone: Women With Advanced PD More Likely to Lack Caregiver

Allison Inserro
Female patients who are homebound with advanced Parkinson disease (PD) are more likely to lack any caregiver and more likely to be single or widowed, according to a report published this week.
Comorbid Psychosis Associated With More Severe Parkinson Disease, Longer Hospital Stays
July 31st 2019

Comorbid Psychosis Associated With More Severe Parkinson Disease, Longer Hospital Stays

Christina Mattina
Findings of a retrospective study show that comorbid psychosis and depression in patients with Parkinson disease are associated with greater disease severity and higher healthcare utilization.
Abnormal Lung Function Found in Patients With Early-Stage Parkinson Disease
July 25th 2019

Abnormal Lung Function Found in Patients With Early-Stage Parkinson Disease

Christina Mattina
Results of a study on patients with early-stage Parkinson disease (PD) add to the evidence showing an association between PD and pulmonary function and point to the potential use of respiratory center drive to identify early PD.
Study Finds Patient–Physician Communication Gaps About Parkinson Off Periods
July 24th 2019

Study Finds Patient–Physician Communication Gaps About Parkinson Off Periods

Allison Inserro
A recently published study used linguistic analysis to investigate communication gaps between patients with Parkinson disease and physicians about off periods using a database containing dialogues recorded during regular office visits. Not only did the recordings show 4 specific areas that need improvement, they also showed a care gap between what the physicians thought they did and what actually happened.
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