Non-Hodgkin Lymphoma (NHL)

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Non-Hodgkin Lymphoma | Image credit: Saiful52 - stock.adobe.com
Higher TMB, PD-L1 Expression Correlate With Shorter Survival in Hematologic Malignancies

October 30th 2024

A new analysis of real-world data show that just as in solid tumors, higher tumor mutational burden (TMB) and PD-L1 expression in blood cancers are linked to less-optimistic prognoses.

Thomas Jefferson | Image: Thomas Jefferson University
Miles Matter: The Geographic Disparity That Impacts Access to CAR T Therapy

October 13th 2024

Microbiologist conducts research in laboratory | Image Credit: © Seventyfour - stock.adobe.com
Preclinical Model Suggests Efficacy of Combining Capivasertib With Venetoclax Against DLBCL

October 8th 2024

Lymphoma word block image | Image Credit: © airdone- stock.adobe.com
Combination of Magrolimab and Rituximab Well Tolerated in Patients With Refractory/Relapsed Indolent NHL

September 25th 2024

NHL cells | image credit: sovova - stock.adobe.com
Lenalidomide-Obinutuzumab Combo Yields Promising Results in Relapsed NHL

September 21st 2024

Continuing Medical Education
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October 30th 2024

ASH Annual Meeting Coverage: Highlighting the Recent Updates in TKI Use in the Treatment of CML – Insights and Application for Managed Care

December 18, 2024 | 1:00 & 8:00 PM ET
October 30th 2024

Recent Advances in BCMA-Directed Treatment in Multiple Myeloma: Insights and Application for Managed Care

1.0 Credits / Hematologic Cancer, Oncology
October 30th 2024

Keeping Pace With New Developments in Multiple Myeloma: Updates and Strategies to Optimize Bispecific Antibodies and CAR T-Cell Therapy

1.5 Credits / Oncology, Hematology, Hematologic Cancer
October 30th 2024

Addressing the Gaps and Clinical Challenges in Chronic Lymphocytic Leukemia: Updates and Strategies for Managed Care

1.5 Credits / Hematology, Hematologic Cancer, Oncology

More News

Endocrinology doctor consulting lymphoma patient with sore neck, aching swollen lymph nodes, throat pain, laryngitis, hodgkin symptoms. Healthcare specialist medical appointment in clinic office: © DC Studio - stock.adobe.com
July 27th 2023

Review Details Current Understanding, Future Directions of DLBCL in Patients With HIV

Gianna Melillo
Diffuse large B-cell lymphoma (DLBCL) is the most common non-Hodgkin subtype in individuals living with HIV.
Heart and DNA Image
July 22nd 2023

In DLBCL Treatment, Cardiovascular Comorbidities Warrant Careful Consideration

Jared Kaltwasser
The most common treatments come with significant cardiovascular risk, but study investigators suggest newer options might offer a more favorable risk profile.
Symbol of pancreatic cancer. Purple awareness ribbon: © Vitalii Vodolazskyi - stock.adobe.com
July 18th 2023

In Pancreatic DLBCL, Older Age, Distant Stage, Lack of Surgery Lead to Worse Outcomes

Jared Kaltwasser
Surgery can be difficult in such cases of diffuse large B-cell lymphoma (DLBCL), but it leads to significant better outcomes, study authors said.
Colorful cell interaction - tumor cell surrounded with immune cells (Generative AI): © Nevio - stock.adobe.com
July 11th 2023

Lymph Node Fibroblasts May Suppress T-Cell Function in DLBCL

Gianna Melillo
These findings from research into diffuse large B cell lymphoma (DLBCL) are based on analyses of human patients and a murine model.
PET/CT is a nuclear medicine device that uses a combination of PET (Positron Emission Tomography) and Computed Tomography technology to diagnose cancer. Brain and nervous system myocardial ischemia: © workphoto - stock.adobe.com
July 8th 2023

Complicated Case of DLBCL Shows Limits of 18F-FDG PET/CT Imaging

Jared Kaltwasser
Investigators said it is important for clinicians to interpret scans with knowledge of case-specific context for patients with diffuse large B-cell lymphoma (DLBCL).
White blood cells in leukemia, AI Generative: © Катерина Євтехова - stock.adobe.com
July 5th 2023

Evolutionary Dynamics Drive Behind Outcomes in Late DLBCL Relapses

Jared Kaltwasser
Serial biopsies help explain why patients with late relapses of diffuse large B-cell lymphoma (DLBCL) fare better than those with early relapses.
Topline Results Show Epcoritamab Offers 82% Response Rate in R/R Follicular Lymphoma
June 28th 2023

Topline Results Show Epcoritamab Offers 82% Response Rate in R/R Follicular Lymphoma

Mary Caffrey
The bispecific antibody received an accelerated approval in May to treat patients with R/R diffuse large B-cell lymphoma.
Finding solutions to complex cases from several perspectives. High angle shot of a group of medical practitioners having a discussion together in a hospital: © Kirsten D/peopleimages.com - stock.adobe.com
June 27th 2023

Patient Complaining of Abdominal Pain Found to Have Unusual Case of DLBCL

Jared Kaltwasser
The patient was put on chemotherapy, but then underwent surgical resection following an accident at home.
New Epcoritamab Data Show Strong Results in B-Cell Lymphomas
June 22nd 2023

New Epcoritamab Data Show Strong Results in B-Cell Lymphomas

Jared Kaltwasser
Data presented at the 2023 European Hematology Association Annual Meeting showed positive outcomes in patients with follicular lymphoma and large B-cell lymphoma, and further evaluation in diffuse large B-cell lymphoma is ongoing.
researchers in a lab
June 17th 2023

Epcoritamab Sparks Durable Responses in Phase 1/2 LBCL Trial

Jared Kaltwasser
At a median follow-up of 10.7 months, the overall response rate was 63.1%.
chest pain
June 16th 2023

Investigators Find DLBCL When Probing Apparent Intramural Hematoma

Jared Kaltwasser
The case report highlights the importance of considering diffuse large B-cell lymphoma (DLBCL) when evaluating patients with persistent periaortic fluid collections.
depressed older man sitting with his head in his hand
June 8th 2023

Preexisting Mental Health Disorders Worsen DLBCL Prognosis

Laura Joszt, MA
Patients with depression, anxiety, or both at the time of diagnosis of diffuse large B-cell lymphoma (DLBCL) have worse overall survival and lymphoma-specific survival.
science background
June 7th 2023

Review: Advances in the Understanding of DLBCL Immunology Could Spark Novel Therapies

Jared Kaltwasser
New therapies could potentially target immune systems at play in certain types of diffuse large B-cell lymphoma.
FDA approved
May 19th 2023

Epcoritamab Approved by FDA to Treat R/R DLBCL

Mary Caffrey
Approval for the T-cell–engaging bispecific antibody came today from the FDA.
ASH 2022: Bispecific Antibodies
February 4th 2023

ASH 2022: Bispecific Antibodies

Mary Caffrey Hayden E. Klein
Coverage from the 64th Annual American Society of Hematology Meeting and Exposition, December 10-13, 2022, New Orleans, Louisiana.
Graphic with the words "Top 5 Clinical Spotlight Interviews of 2022"
December 29th 2022

Top 5 Clinical Spotlight Interviews of 2022

AJMC Staff
Throughout 2022, expert interviews on clinical topics covered cytogenetics in multiple myeloma, access to better treatments in diffuse large B-cell lymphoma, and challenges with devices in chronic obstructive pulmonary disease.
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