Real-world outcomes for HER2-positive NSCLC differ from clinical trials due to diverse patient populations and treatment settings.
Clinical trials involve selected patients, while real-world settings include those with comorbidities and varying performance statuses.
Common adverse events with HER2-directed therapies include diarrhea, fatigue, and cardiac dysfunction.
Management of adverse events involves dose adjustments, supportive care, and close monitoring to optimize treatment strategies.
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Dr Heymach real-world outcomes versus clinical trials for HER2-positive NSCLC and the management of common adverse events associated with HER2-directed therapies.