Opinion|Videos|July 11, 2024
Exploring Results from CAPItello-291 Trial
William J. Gradishar, MD, examines the impact of the CAPItello-291 phase III trial on NCCN breast cancer guidelines, comparing the investigated drug to other PI3K pathway inhibitors and discussing its potential to shape future treatment strategies.
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Episodes in this series
- In November 2023, capivasertib received FDA approval for use in advanced hormone receptor-positive breast cancer based on the results from the
CAPItello-291 phase III trial. How has capivasertib been integrated into the NCCN guidelines for breast cancer?- What are your thoughts on sequencing of capivasertib use in the management of HR+ breast cancer?
- How does capivasertib compare to other PI3K pathway inhibitors alpelisib and inavolisib from safety and efficacy standpoints?
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