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BTK Inhibitors' Rationale and Potential Role in Multiple Sclerosis Treatment

Heidi Crayton, MD, discusses the rationale for investigating Bruton tyrosine kinase inhibitors (BTKis) as a treatment for patients with multiple sclerosis and the current stage of development for evobrutinib, tolebrutinib, and other BTKis.

Video content above is prompted by the following questions:

  • What was the rationale for the investigation of Bruton tyrosine kinase inhibitors (BTKis) for use as treatment in patients with multiple sclerosis (MS)?
  • What is the stage in development for evobrutinib, tolebrutinib and other BTKis?
  • How might these therapies fit into treatment algorithms for different types of MS?
  • How do payers see these therapies being integrated into treatment algorithms?
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