April 28th 2025
New research suggests classical biomarkers cannot discriminate between refractory and non-refractory rheumatoid arthritis.
DMD Guidance Could Benefit From Update, Experts Say
January 24th 2024MEDLINE, the Turning Research Into Practice database, Google Scholar, and organization guidelines were searched for their ongoing applicability to the management of Duchenne muscular dystrophy (DMD) and to determine if there is a need to develop new treatment recommendations.
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Extended Study Shows Consistent Safety, Efficacy in Complex Mental Health Treatment
January 24th 2024Topline results from a pivotal phase 3, open-label extension study showcase the long-term safety and efficacy of olanzapine and samidorphan (Lybalvi) in patients with schizophrenia, schizophreniform disorder, or bipolar I disorder.
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Similar Risk of Death Between Patients With HFimpEF, LVEF Above 40% in DELIVER Trial
January 24th 2024An analysis of the DELIVER trial also revealed an association between dapagliflozin treatment and reduced risk of cardiovascular death among individuals with heart failure with improved ejection fraction (HFimpEF).
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Sacituzumab Govitecan Monotherapy for NSCLC Disappoints in EVOKE-01 Trial Update
January 23rd 2024The TROP-2–directed antibody drug conjugate is currently being investigated as a monotherapy and a combination therapy for non–small cell lung cancer (NSCLC) in 3 trials: phase 3 EVOKE-01, phase 2 EVOKE-02, and phase 3 EVOKE-03.
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Study Highlights Need for Additional Caregiver Support in Higher-Risk MDS
January 23rd 2024The study, which pulled self-reported data from online bulletin boards across the US, Canada, and the United Kingdom in 2020, found that the degree of burden varied based on patient disease stage, among other factors.
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Molly Mendenhall on Standardizing Comprehensive Biomarker Testing in NSCLC
January 18th 2024Molly Mendenhall, BSN, RN, director of quality and compliance at Oncology Hematology Care, Inc (OHC), discussed a 1-year quality improvement project implemented by OHC to standardize comprehensive biomarker testing in patients with non–small cell lung cancer (NSCLC).
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New Study Series Addresses Racial Inequities in Pediatric Care, Need for Policy Reform
January 17th 2024The findings demonstrate the critical need for immediate policy reforms to tackle structural racism and promote equitable pediatric care in the US for children regardless of race or ethnicity.
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Online Workshop Reveals Patient, Future Research Priorities in MDS
January 17th 2024Myelodysplastic syndrome is an extremely heterogeneous disease, and there is no definitive cure, so these investigators wanted a better understanding of patients’ priorities regarding their care, quality of life, and communication with the care team.
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Real-Time CGM Shows Benefits Over Intermittently Scanned CGM in T1D
January 16th 2024In a systematic review and meta-analysis, real-time continuous glucose monitoring (CGM) demonstrated benefits in terms of time in range, hypoglycemia, and hyperglycemia among patients with type 1 diabetes (T1D).
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Gabapentinoid Use in COPD Associated With Increased Severe Exacerbation Risk, Study Says
January 15th 2024Gabapentinoid use, namely gabapentin and pregabalin, was associated with increased risk for severe chronic obstructive pulmonary disease (COPD) exacerbation in patients with epilepsy, neuropathic pain, and other chronic pain.
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Study Explores Treatment Discontinuation Rates, Resource Utilization Among Patients With CLL/SLL
January 12th 2024A real-world study found that patients treated with Bruton tyrosine kinase inhibitors had lower rates of treatment discontinuation and health care resource utilization compared with other first- and second-line treatment regimens.
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