April 28th 2025
New research suggests classical biomarkers cannot discriminate between refractory and non-refractory rheumatoid arthritis.
COVID-19 Vaccination Rates Far Lower in Patients With SCD Compared With General Population
February 4th 2024A state-wide analysis draws attention to the fact individuals with sickle cell disease (SCD) completed a vaccination against COVID-19 at nearly half the rate of individuals without SCD.
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Health Equity and Access Weekly Roundup: February 3, 2024
February 3rd 2024The Center on Health Equity and Access provides real-time updates, shares cutting-edge research, and supports continuous efforts dedicated to tackling health care disparities and enhancing widespread access to high-quality health services.
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Contributor: Navigating Health Equity in 2024: The Evolution of Accountability, Part 2
February 2nd 2024The article emphasizes the significance of accreditations in addressing health disparities and promoting health equity, highlighting programs for achieving accreditation and advocating for the integration of social determinants of health (SDOH) and health equity practices within pharmacy and health care.
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Dr Ann LaCasce Looks to the Year Ahead in the Lymphoma Treatment Landscape
February 2nd 2024Ann LaCasce, MD, MMSc, director of the Dana-Farber/Mass General Brigham Fellowship in Hematology/Oncology and chair of the Lymphoma Research Foundation’s Scientific Advisory Board, discusses potential shifts in the lymphoma space in the year ahead.
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CD137+ Tumor Infiltrating Lymphocytes Correlate With OS in Ovarian Cancer, Study Finds
February 2nd 2024In patients with high-grade ovarian cancer, an increased proportion of CD3+ CD137+ tumor infiltrating lymphocytes (TILs) correlated with favorable overall survival outcomes. However, proportions of CD3+ or CD3+ CD8+ TILs did not show significant associations with OS.
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Uncertainty, Coping Strategies Common Among Patients With AML, High-Risk MDS
February 2nd 2024Patients with comorbid acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS) expressed a desire to discuss treatment options and maintain normalcy; they were not willing to have conversations involving their prognosis and future.
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Hospitalization, ER, and Medication Discontinuation Rates Still High in PNH
February 2nd 2024A retrospective analysis surveys the treatment landscape and patterns of patients with paroxysmal nocturnal hemoglobinuria (PNH), illuminating high hospitalization rates and emergency department use despite the availability of multiple treatment options.
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Evidence Linking Sleep to Improved Lower Back Pain Outcomes Is Weak, More Studies Needed
February 2nd 2024A systematic review of randomized controlled trials and prospective cohort studies concludes that sleep could be a prognostic component of lower back pain, but better evidence is needed.
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Depression in Heart Failure: Data Support Psychotherapy or Medication Intervention
February 1st 2024The findings not only underscore the efficacy of 2 major interventions—Behavioral Activation Psychotherapy (BA) and Antidepressant Medication Management (MEDS)—but also support patient autonomy in choosing their preferred path to mental well-being.
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Further Studies Required as MS DMT Exposure During Pregnancy Increases
February 1st 2024A large-scale, population-based study examined patterns of disease-modifying therapy (DMT) exposure in pregnant patients with MS since 2010, revealing increased occurrences and the need for future studies to examine the impact of newer-developed DMTs.
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40-GEP Test Utilization Can Mitigate Financial Burden of Cutaneous Squamous Cell Carcinoma
February 1st 2024Medicare-eligible patients with cutaneous squamous cell carcinoma (cSCC) could save on health care costs by utilizing the 40-gene expression profile (40-GEP) to guide treatment decisions.
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Familial Hypercholesterolemia May Double Coronary Heart Disease Risk in Moderately Elevated LDL-C
January 31st 2024However, the association between familial hypercholesterolemia variants and coronary heart disease slightly weakened after adjusting for baseline low-density lipoprotein cholesterol (LDL-C) level and became statistically insignificant after adjusting for cumulative past LDL-C exposure.
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Health Discrepancies in Criminal Justice System Intrinsically Tied to Public Health
January 31st 2024Research on the state of health care, health outcomes, and health inequities in the criminal justice system continually advocates for structural-level reform and the recognition that carceral health issues are in fact public health issues.
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IV Methylprednisolone, Tacrolimus Effective in Prednisone-Resistant Ocular MG
January 31st 2024Researchers have retrospectively analyzed data from nearly 60 patients with ocular myasthenia gravis (MG) not adequately responding to oral prednisone, finding that both intravenous (IV) methylprednisolone and tacrolimus monotherapy helped reduce symptoms.
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Best Practices That Target Selinexor Treatment Improve MM-Related Outcomes
January 29th 2024Patient survival and such treatment-related outcomes as time to treatment failure and treatment duration improved following implementation of a best practices program that focused on selinexor administration for multiple myeloma (MM), with implications for other anticancer medications.
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ELN Risk Category, MRD Status Predictive of Relapse in Patients With AML
January 29th 2024The study may help explain why some patients are more prone to relapse following a complete response to induction therapy, as indicated by measurable residual disease (MRD) status and 2017 European LeukemiaNet (ELN) criteria.
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Meta-Analysis Investigates Individual Components of CBT for Insomnia
January 29th 2024A meta-analysis explored the individual components of cognitive behavioral therapy for insomnia (CBT-I) and suggested that cognitive restructuring, stimulus control and sleep restrictions provide the more benefits to patients.
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Myeloid Panel Analysis Imperative for Risk Assessment in Patients With CCUS
January 29th 2024A myeloid panel mutation analysis should be prioritized for patients with clonal cytopenia of undetermined significance (CCUS) as it can better assess patient risks for progression to a myeloid malignancy, a recent study argues.
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Low Muscle Mass, Hypoalbuminemia Increase Mortality Risk in ADHF
January 28th 2024Patients admitted to the hospital with acute decompensated heart failure (ADHF) who also had low muscle mass and hypoalbuminemia experienced a heightened mortality risk, suggesting skeletal muscle mass and serum albumin are important prognostic factors.
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Health Equity and Access Weekly Roundup: January 27, 2024
January 27th 2024The Center on Health Equity and Access delivers current updates, highlights breakthroughs in research, and ongoing endeavors committed to addressing healthcare inequalities and improving universal access to exceptional health care.
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Contributor: It’s About Time to Realize the Full Potential of Data in Health Care
January 26th 2024Promoting health equity isn’t only about consideration of underlying health risks; it’s also about using that data to inform population care as well as give clinicians and their teams more time with the patient in front of them.
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Female Patients Less Likely to Receive Guideline-Directed HFrEF Therapies vs Males
January 25th 2024A recent study found that use of optimal guideline-directed medical therapies after heart failure with reduced ejection fraction (HFrEF) diagnosis is low overall, but especially among female patients compared with male patients.
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