All News

A decision was upheld that Johnson & Johnson (J&J) must pay a $2.1-billion fine from a 2018 court decision; 3 major drug distributors face up to $18 billion in opioid-related fines; a new diabetes prevention platform may assist in symptom prevention.

The CGRP story is really based on reverse translation and other observations in humans will be pursued along that same model, said Frank Porreca, PhD, professor of pharmacology and anesthesiology at the University of Arizona and a member of the Department of Collaborative Research at Mayo Clinic in Arizona.

Regeneron’s PD-1 inhibitor Libtayo was accepted for priority FDA review for the treatment of first-line locally advanced or metastatic non–small cell lung cancer (NSCLC) with PD-L1 expression of at least 50%.

Older Americans with vision impairment may be less likely to use cancer-related preventive services compared with their counterparts without vision impairment.

There did not appear to be any particular patient characteristics linked with best responses to carfilzomib in patients with multiple myeloma, with the exception of low serum lactate dehydrogenase.

Researchers discuss the development and potential of stem cell–based therapies in the treatment of Parkinson disease.

Variability in prevalence of vestibular migraine, depending on ethnicity and geographic location suggests, a combined genetic and environmental contribution to VM, according to results of a systematic review.

Patients with mild cases of coronavirus disease 2019 (COVID-19) had cellular immunity after 6 months; political support among caregivers of patients with COVID-19 was spotlighted; 2 lots of type 2 diabetes (T2D) drug metformin recalled over possible contamination.

Immune-associated neurotoxicity in patients following chimeric antigen receptor (CAR) T-cell therapy may be due to monocyte-like cells in infusion products, explained Michael R. Green, PhD, University of Texas MD Anderson Cancer Center.

As novel therapies drive up the cost of cancer care, federal policy decisions are being made that influence oncologists' ability to deliver cancer care, said Debra Patt, MD, PhD, MBA, MPH, of Texas Oncology.

Smaller babies born to mothers living with HIV are often considered “undesirable” in sub-Saharan Africa, and the mothers themselves often are blamed for this.

Two CHEST 2020 abstracts looked at mortality risks for patients with chronic obstructive pulmonary disease (COPD).

Amid the coronavirus disease 2019 pandemic, patients with narcolepsy reported changes in bedtime and waking schedules, as well as an increase in adverse symptoms such as cataplexy and sleep paralysis.

Nearly half of hospitals to get lower Medicare payments due to patients' readmission history; open enrollment begins for health coverage under the Affordable Care Act; study models projected cases and deaths from COVID-19 to the president's rallies.

Every week, The American Journal of Managed Care® recaps the top managed care news of the week, and you can now listen to it on our podcast, Managed Care Cast.

Despite FDA accelerated approval in April, we still need to learn more about resistance to this antibody drug conjugate, said Aditya Bardia, MBBS, MPH, breast medical oncologist, Massachusetts General Hospital, Harvard Medical School.

Through the Oncology Care Model's impact on preventing unnecessary utilization, particularly for in-patient care, resources derived from its use has enhanced care coordination and led to the formation of novel infrastructure and clinical pathways.

Migraine can affect children’s quality of life, and a recent study examined the use of melatonin to treat pediatric acute migraine.

Lametra Scott, PharmD, CCHP, CEO of Breaking The Sickle Cell Cycle Foundation Inc, discussed the pathophysiology of sickle cell disease (SCD) the dangers of leaving it untreated.

The federal illegality and Schedule I listing of cannabis significantly impair our ability to conduct any kind of prospective clinical research, said Joshua L Rein, DO, FASN, a nephrologist at Mt. Sinai Hospital in New York City.

The study compared patients given-low-dose ketamine with those given morphine for acute pain relief.

Researchers conducting broad next-generation sequencing discovered more actionable variants in patients and families than they would have otherwise; they did so by using a universal approach, rather than sticking with clinical guidelines.

The American College of Rheumatology (ACR) has joined forces with other provider groups to oppose a plan proposed by UnitedHealthcare that would increase patients’ out-of-pocket costs.

The novel patient-centered performance metric was associated with readmission and mortality outcomes, as well as reclassification of hospital performance, compared with a CMS 30-day metric.

Up until now, it was thought most patients with hemophilia A developed inhibitors in middle-age. A new study suggests it usually happens in the early teens.

The patients must always come first, emphasized Milena Murray, PharmD, MSc, BCIDP, AAHIVP, associate professor at Midwestern University College of Pharmacy, who practices at the Northwestern Medicine Infectious Disease Center in Chicago.

A pair of abstracts presented at Kidney Week 2020 underscore the relationship between social determinants of health (SDOH) and chronic kidney disease (CKD) in military populations and the challenges of tracking these factors.

Spend time with your patients, discussing both the risks and benefits of a potential coronavirus disease 2019 vaccine, emphasized Maura Abbott, PhD, AOCNP, CPNP, RN, assistant professor of nursing at the Columbia University School of Nursing.