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A bipartisan congressional report estimates overdose deaths cost the United States $1 trillion yearly; 4 states announce plans to lift their statewide mask mandates for schools; study finds greater risk of pregnancy complications in expectant mothers with moderate COVID-19 symptoms.

Findings of the largest genome-wide association study conducted among migraineurs to date revealed novel risk factors for the condition, stratified by aura presence.

Cardinal Health's report, “2022 Biosimilars Report: The U.S. Journey and Path Ahead,” outlines how biosimilars will move beyond their comfort zones in oncology and rheumatology and more boldly into therapeutic areas such as ophthalmology and diabetes care.

Patients with chronic kidney disease (CKD) and their caregivers who have participated in CKD research shared factors that may encourage or discourage others from enrolling in clinical studies, highlighting the ways that investigators can better involve patients in research.

A study from investigators at Fox Chase Cancer Center sought comparative outcomes data on adverse reactions from COVID-19 vaccination among patients with a history of cancer and those undergoing treatment and found equivalent safety outcomes.

The drug will be marketed by Sanofi under the name Enjaymo; it is the first treatment approved for cold agglutinin disease.

Poor agreement was identified regarding MRI- and classification-defined axial spondyloarthritis (axSpA) and inflammatory back pain diagnoses in patients with psoriatic disease.

Sunil Verma, MD, senior vice president and global head of oncology, medical at AstraZeneca, explains the background and results of the TOPAZ-1 study.

The CDC's wastewater monitoring program will soon begin evaluating more water samples for COVID-19; vaccine guidance changes for individuals who are immunocompromised may be forthcoming; exposure to air pollution levels vastly greater than that advised by World Health Organization guidelines.

Part 1 of a 2-part webinar series by the National Alliance of Healthcare Purchaser Coalitions addressed issues in health care coverage affordability and how equitable health benefits and value-based design can reduce cost while improving employee engagement.

This study from Italy investigated potential associations between heart failure and comorbid cancer and whether the existence of heart failure predisposed individuals with both to a higher risk of death.

Data from a 10-year follow-up study showed declining kidney function is significantly associated with dementia risk among older adults.

Nasal surgical intervention led patients with obstructive sleep apnea (OSA) who historically were nonadherent to continuous positive airway pressure (CPAP) treatment to become adherent and experience improvements in objective and subjective severity measures.

This retrospective study using administrative claims data examining health care resource utilization (HCRU) found that in the months before a diagnosis of eosinophilic esophagitis (EoE), other diseases were more commonly diagnosed.

Sunil Verma, MD, senior vice president and global head of oncology, medical at AstraZeneca, summarizes the benefits and safety findings discovered in the HIMALAYA study.

Although cardiovascular disease risk is well established in survivors of breast cancer, how cardiotoxicity from treatment influences development of cardiometabolic risk factors is not.

Research showed that younger and nonfrail patients with COVID-19 were more likely to be put on a ventilator, while patients with frailty and older age had a higher risk of in-hospital and in-ICU mortality.

Idiopathic pulmonary arterial hypertension and pulmonary hypertension due to chronic lung disease can be difficult to differentiate, but new research suggests descriptions of lung parenchyma in routine CT scans may prove useful.

A recent study examined asthma control and quality of life in pregnant women with asthma.

A recently published meta-analysis examined the extent to which cognitive rehabilitation is useful in Parkinson disease (PD), since other reports on the matter have been mixed.

Researchers discuss contributors to nasal polyp development in children, as well as the risk of co-occuring conditions and current methods of treatment.

Megan Olsen, MPH, principal at Avalere, explores the challenges that arise for Medicaid plans when providers choose to prescribe a cell or gene therapy.

This systematic review revealed that although the reporting of racial and ethnic data has increased in recent years, inclusion of minority groups has remained unchanged.

A meta-analysis from 3 economists concluded that nonpharmaceutical interventions in response to COVID-19 failed to have a large, significant effect on mortality rates.

The overdiagonsis identified in the current study also led to overtreatment in this population, authors found.

Kathy Oubre, MS, chief operating officer of Pontchartrain Cancer Center, talks about how biosimilars have been able to help patients avoid financial toxicity related to oncology care costs.

Researchers assess the role of cognitive behavioral therapy in treating pediatric migraine.

Nocturnal road traffic noise was strongly linked to a range of insomnia symptoms, highlighting the potential impact of noise pollution on public health in large populations.