Sleep

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Sleepless woman suffering | Image Credit: ©- terovesalainen stock.adobe.com
Researchers Find Higher Risk of Insomnia With Undiagnosed Asthma

November 10th 2024

Based on their findings, the researchers suggest a potential need for screening for coexisting sleep disorder symptoms in patients with respiratory symptoms.

Narcolepsy and idiopathic hypersomnia are each characterized by excessive daytime sleepiness | image credit: ARMMY PICCA - stock.adobe.com
Novel Orexin 2 Receptor Agonist Shows Promise for Management of Narcolepsy and Idiopathic Hypersomnia

November 7th 2024

Pregnant women may experience insomnia | image credti: JenkoAtaman - stock.adobe.com
Pregnancy-Related Insomnia: Music and Sleep Hygiene Interventions Offer Effective Relief

October 25th 2024

Psoriasis may increase one's risk of developing sleep apnea | image credit: SNAB - stock.adobe.com
Patients With Psoriasis Face Increased Risk of Obstructive Sleep Apnea, Study Finds

October 17th 2024

Zinc may help individuals get better sleep, but research in this area provides mixed conclusions | image credit: Ron Dale - stock.adobe.com
Zinc's Link to Sleep Quality Remains Unclear, Further Studies Needed

October 8th 2024

Continuing Medical Education
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November 21st 2024

Assessing the Treatment Landscape for Multiple Sclerosis to Better Individualize Care

1.5 Credits / Neurology
November 21st 2024

Exploring Transthyretin-Mediated Amyloidosis and Its Phenotypes: A Comprehensive Approach to Patient Treatment

1.5 Credits / Cardiology, Neurology, Rare Diseases
November 21st 2024

The Role of the Specialty Pharmacist in Optimizing Treatment for Amyotrophic Lateral Sclerosis: The Impact of Early Intervention, Patient-Centered Care, and Disease-Modifying Therapies in Slowing Disease Progression

1.0 Credit / Neurology
November 21st 2024

Advancing Targeted Therapies Aimed at Smoldering Disease in Multiple Sclerosis

1.0 Credit / Immunology, Neurology
November 21st 2024

The Economics of Transthyretin-Mediated Amyloidosis: Balancing Equity and Access in Resource Allocation

1 Credit / Cardiology, Neurology
November 21st 2024

Managing Patients With COPD: Evidence-Based Care and Optimizing Value of New and Emerging Targeted Therapies

1.0 Credit / Immunology, Pulmonology/Respiratory

More News

Researchers Modify Sleep Apnea Machines to Ease Ventilator Shortage
April 15th 2020

Researchers Modify Sleep Apnea Machines to Ease Ventilator Shortage

Gianna Melillo
To help ease ventilator shortages resulting from the coronavirus disease 2019 pandemic, researchers at New York University’s Tandon School of Engineering were able to modify continuous positive airway pressure machines, used to treat patients with sleep apnea, into alternatives for mechanical ventilators.
Study Finds More Than One-Third of Healthcare Workers Suffered From Insomnia During COVID-19 Epidemic in China
April 14th 2020

Study Finds More Than One-Third of Healthcare Workers Suffered From Insomnia During COVID-19 Epidemic in China

Matthew Gavidia
More than a third of healthcare workers responding to the coronavirus disease 2019 (COVID-19) pandemic in China during its peak suffered from insomnia, with those reporting sleeplessness also more likely to feel depressed, anxious, and have stress-based trauma, according to study findings published today.
Workers With Excessive Daytime Sleepiness, OSA at Higher Risk of Occupational Accidents
April 9th 2020

Workers With Excessive Daytime Sleepiness, OSA at Higher Risk of Occupational Accidents

Matthew Gavidia
Employees with either obstructive sleep apnea or excessive daytime sleepiness were shown to be 2 times more likely to be involved in occupational incidents, highlighting the serious safety hazard posed by both conditions.
Herb Extract Shown to Enhance Sleep Quality, Mental Alertness in the Elderly
April 7th 2020

Herb Extract Shown to Enhance Sleep Quality, Mental Alertness in the Elderly

Matthew Gavidia
Ashwagandha root extract, a revered herb of Ayurveda, was associated with improvements in quality of life, sleep quality, and mental alertness in elderly patients, according to study findings.
Excessive Daytime Sleepiness Therapy in Patients With Parkinson Disease Meets Phase 2 Primary Efficacy End Point
April 2nd 2020

Excessive Daytime Sleepiness Therapy in Patients With Parkinson Disease Meets Phase 2 Primary Efficacy End Point

Matthew Gavidia
Theranexus announced this week that its phase 2 trial for THN102 (modafinil/flecainide) in patients with Parkinson disease met its primary efficacy end point of significantly increasing the proportion of patients no longer suffering from excessive daytime sleepiness.
Sleep, Physician Burnout Linked Amid COVID-19 Pandemic
March 31st 2020

Sleep, Physician Burnout Linked Amid COVID-19 Pandemic

Matthew Gavidia
Amid the coronavirus disease 2019 (COVID-19) pandemic, the American Academy of Sleep Medicine (AASM) has issued a position statement on the significance of sufficient sleep, which when impaired has been deemed a possible contributing factor to physician burnout.
FDA Accepts Filing for Investigational Narcolepsy Medication
March 26th 2020

FDA Accepts Filing for Investigational Narcolepsy Medication

Gianna Melillo
The FDA has accepted for filing with priority review Jazz Pharmaceuticals’ new drug application for JZP-258. The investigational medicine targets cataplexy and excessive daytime sleepiness associated with narcolepsy.
Sleep-Disordered Breathing Shown to Contribute to Brain Alterations Typically Seen in Alzheimer Disease
March 23rd 2020

Sleep-Disordered Breathing Shown to Contribute to Brain Alterations Typically Seen in Alzheimer Disease

Matthew Gavidia
In older adults who are cognitively unimpaired, sleep-disordered breathing was found to alter Alzheimer disease–sensitive brain regions, causing greater amyloid deposition and neuronal activity, according to study findings.
Diuretics Linked With OSA Severity Reduction in Patients With Moderate Obesity, Hypertension
March 19th 2020

Diuretics Linked With OSA Severity Reduction in Patients With Moderate Obesity, Hypertension

Matthew Gavidia
In patients with hypertension who are overweight or moderately obese, diuretics were shown to potentially reduce the severity of obstructive sleep apnea, according to study findings.
Men, Women Display Symptoms Related to Sleep, Fatigue Differently, Study Finds
March 16th 2020

Men, Women Display Symptoms Related to Sleep, Fatigue Differently, Study Finds

Alison Rodriguez
Men demonstrated higher levels of respiratory events and more periodic limb movements but women had significantly higher levels of sleep-associated complaints across all measures.
Impaired Sleep Duration, Quality in Infancy Associated With Behavioral Health Issues in Children
March 13th 2020

Impaired Sleep Duration, Quality in Infancy Associated With Behavioral Health Issues in Children

Matthew Gavidia
Toddlers with reported diminished sleep duration and quality during infancy had a greater likelihood of emotional and behavioral problems, with associations proving strongest for internalizing and dysregulation symptoms, according to study findings.
Better Sleep Linked With Reduced Risk of CVD, Improved Weight Loss
March 4th 2020

Better Sleep Linked With Reduced Risk of CVD, Improved Weight Loss

Matthew Gavidia
Improved sleep patterns were linked with potential risk reductions of heart attacks, strokes, and other cardiovascular diseases, with additional associations found in helping women achieve and maintain a healthier body weight, according to preliminary research to be presented at American Heart Association's Epidemiology and Prevention | Lifestyle and Cardiometabolic Health Scientific Sessions 2020.
Sleep Disorders Common in Patients With T1D, Review Shows
March 2nd 2020

Sleep Disorders Common in Patients With T1D, Review Shows

Jared Kaltwasser
A new review article shows scientific studies have consistently identified links between sleep problems and health outcomes in patients with type 1 diabetes (T1D). Despite the apparent links, there are no screening recommendations related to sleep in patients with the disease.
How Does Sleep Duration Influence Mental Health of Children?
February 28th 2020

How Does Sleep Duration Influence Mental Health of Children?

Matthew Gavidia
Sleep duration among adolescents aged 9 to 11 was shown to influence elements of mental health, including depression, anxiety, impulsive behavior, and cognitive performance, according to study findings.
Narcolepsy Pipeline Features Optimistic New Strategies, Review Finds
February 23rd 2020

Narcolepsy Pipeline Features Optimistic New Strategies, Review Finds

Jared Kaltwasser
Drug developers have made significant strides in understanding narcolepsy in recent years. Now, those advances are translating into a robust pipeline of potential new therapies.
Review Outlines Guidance for Military Personnel, Veterans With Sleep Disorders
February 20th 2020

Review Outlines Guidance for Military Personnel, Veterans With Sleep Disorders

Gianna Melillo
In 2019, the US Department of Defense (DoD) and Department of Veterans Affairs (VA) approved clinical practice guidelines regarding management and treatment of chronic insomnia disorder and obstructive sleep apnea in VA and DoD patients. The VA/DoD Evidence-Based Practice Work Group formulated the framework to enable more effective screening, treatment, and managements of these diseases, according to a review published in Annals of Internal Medicine.
Narcolepsy Monitoring App Shows Possible Effectiveness in Symptom Tracking, Study Says
February 16th 2020

Narcolepsy Monitoring App Shows Possible Effectiveness in Symptom Tracking, Study Says

Alison Rodriguez
The Narcolepsy Monitor—a companion app for long-term narcolepsy symptom monitoring—may be a helpful tool for gaining insight into the individual burden of narcolepsy symptoms over time and may serve as a patient-reported outcome measure, according to study findings.
Addressing Sleep Issues in Children, Teens With Autism
February 13th 2020

Addressing Sleep Issues in Children, Teens With Autism

Matthew Gavidia
In new guidelines issued today by the American Academy of Neurology (AAN), researchers provide sleep intervention recommendations to families, neurologists, and other healthcare providers in making decisions on the best treatments available for children and teens with autism.
Deep Learning Model Found to Accurately, Automatically Detect Sleep Staging for Patients With Suspected OSA
February 4th 2020

Deep Learning Model Found to Accurately, Automatically Detect Sleep Staging for Patients With Suspected OSA

Matthew Gavidia
Using a deep learning–based model to characterize sleep staging, researchers were able to accurately and automatically detect patients with and without obstructive sleep apnea (OSA), but accuracy decreased with increasing OSA severity, according to study findings.
Untreated Obstructive Sleep Apnea Results in Higher Costs, Healthcare Utilization
February 1st 2020

Untreated Obstructive Sleep Apnea Results in Higher Costs, Healthcare Utilization

Alison Rodriguez
Medicare beneficiaries with untreated obstructive sleep apnea (OSA) have increased healthcare utilization (HCU) and costs across all points of service, according to results of a recent study published by the Journal of Clinical Sleep Medicine.
Tolerance Complicates Sleep Benefit From Medical Cannabis Among Patients With Chronic Pain, Insomnia
January 29th 2020

Tolerance Complicates Sleep Benefit From Medical Cannabis Among Patients With Chronic Pain, Insomnia

Matthew Gavidia
Medical cannabis was found to exhibit an overall positive effect on maintaining nightime sleep in patients with chronic pain, but frequent use was associated with problems of both waking up at night and falling asleep, according to study findings.
Jazz Pharmaceuticals Submits NDA for Therapy to Treat Excessive Daytime Sleepiness
January 23rd 2020

Jazz Pharmaceuticals Submits NDA for Therapy to Treat Excessive Daytime Sleepiness

Matthew Gavidia
Jazz Pharmaceuticals announced today it had redeemed its priority review voucher to submit a New Drug Application to the FDA on January 21, 2020; the company seeks approval for JZP-258, an investigational medication to treat cataplexy and excessive daytime sleepiness in patients 7 years and older with narcolepsy.
What We're Reading: Employee Sleep Improvements; Republican Supports Medicare Drug Price Negotiations; Sepsis Death Toll
January 17th 2020

What We're Reading: Employee Sleep Improvements; Republican Supports Medicare Drug Price Negotiations; Sepsis Death Toll

AJMC Staff
Along with weight loss, exercise, and nutrition, employers now target sleep improvements in employees; a Republican member of the FTC supports Medicare drug price negotiations; sepsis is likely responsible for 20% of deaths worldwide.
Blood Testing May Prove Effective Metric for Adolescent Sleep Duration, Study Shows
January 15th 2020

Blood Testing May Prove Effective Metric for Adolescent Sleep Duration, Study Shows

Matthew Gavidia
Sleep duration was found to reflect the profile of specific circulating microRNAs in the blood of school-aged children and adolescents, indicating the potential efficacy of a blood test to examine those at risk of negative health outcomes related to insufficient sleep, according to study findings.
Increased T-Cell Response to Orexins in Children With Narcolepsy Type 1, Study Finds
January 13th 2020

Increased T-Cell Response to Orexins in Children With Narcolepsy Type 1, Study Finds

Alison Rodriguez
Narcolepsy type 1 (NT1) may be caused by an autoimmune T-cell response to orexins and could be triggered by flu antigens, according to study findings.
Minimal, Extended Sleep Duration Linked to Development of Pulmonary Fibrosis
January 6th 2020

Minimal, Extended Sleep Duration Linked to Development of Pulmonary Fibrosis

Matthew Gavidia
People who regularly sleep less than 4 hours or more than 11 hours were found to be 2 to 3 times more likely to have pulmonary fibrosis compared with those who sleep for 7 hours a day, according to study results.
Study Links Short Sleep Duration to Male Sex, Old Age, and High Coffee Intake
January 5th 2020

Study Links Short Sleep Duration to Male Sex, Old Age, and High Coffee Intake

Alison Rodriguez
The researchers reported that aging brings degeneration of the circadian pacemaker, a progressive decline in melatonin output and decrease in rhythm amplitude which contributes to increasing sleep fragmentation and waking up earlier in the morning.
Fluoride Exposure Linked to Changes in Sleep Cycle, Study Suggests
January 1st 2020

Fluoride Exposure Linked to Changes in Sleep Cycle, Study Suggests

Alison Rodriguez
Water fluoride concentrations were associated with higher odds of reports of snorting, gasping, or stopping breathing while sleeping at night.
Long Midday Naps, Sleep Duration Linked to Increased Risk of Stroke
December 22nd 2019

Long Midday Naps, Sleep Duration Linked to Increased Risk of Stroke

Matthew Gavidia
People who sleep 9 or more hours a day, take midday naps lasting more than 90 minutes, or have poor sleep quality may be at an increased risk of stroke, according to study findings.
Narcolepsy Management Must Be Tailored for Each Patient, Report Suggests
December 18th 2019

Narcolepsy Management Must Be Tailored for Each Patient, Report Suggests

Alison Rodriguez
Narcolepsy management should be a combination of behavioral and pharmacologic strategies that are tailored to the patient with consideration of the impact of symptoms and how they may evolve, according to a recent review aiming to improve narcolepsy diagnosis and management.
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