Psoriasis

The AJMC® Psoriasis compendium is a comprehensive resource for clinical news and expert insights for the chronic skin disease, which tends to go through cycles where it flares and goes into remission.

Latest News

Plaque psoriasis | Image credit: Milan Lipowski - stock.adobe.com
Icotrokinra Shows Clear Skin in 75% of Adolescents With Plaque Psoriasis in Phase 3 Trial

April 10th 2025

New data presented at the 2025 World Congress of Pediatric Dermatology annual meeting highlights the efficacy and safety of once-daily icotrokinra (JNJ-2113) in adolescents with moderate to severe plaque psoriasis.

Psoriasis oral treatment | Image credit: Pawel - stock.adobe.com
Women Have Lower Drug Survival With Biologics for Psoriasis, Including IL-17 and IL-23 Inhibitors

April 7th 2025

Psoriasis treatment concept | Sviatlana - stock.adobe.com
Tildrakizumab Effective Up to Nearly 3 Years Regardless of BSA Affected, Obesity

April 1st 2025

Bimekizumab | Image credit: luchschenF - stock.adobe.com
Bimekizumab Reduces Inflammation, Cardiovascular Risk

March 21st 2025

Psoriasis in older woman | Image credit: ajr_images - stock.adobe.com
Biologics Linked to Lower Infection Risk in Older Adults With Psoriatic Disease

March 19th 2025

A Personalized Approach to Disease Management in Psoriasis

A panel of experts discuss their personalized approaches to treating patients with psoriasis and comorbidities such as metabolic syndrome.

Ryan Haumschild, PharmD, MS, MBA, Bhavesh Shah, PharmD, Mark Lebwohl, MD, and Robert Groves, MD.
Continuing Medical Education
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April 15th 2025

Treatment Gaps in the Management of Generalized Pustular Psoriasis: Enhancing the Role of Managed Care

1.5 Credits / Dermatology, Immunology
April 15th 2025

Advancing Patient Outcomes in Hidradenitis Suppurativa: Updates and Strategies for Managed Care

1.5 Credits / Dermatology

More News

Defective Stem Cell Behavior Linked to Psoriasis
December 14th 2019

Defective Stem Cell Behavior Linked to Psoriasis

AJMC Staff
More treatments are needed for the 100 million individuals worldwide affected by psoriasis. Researchers from Brigham and Women's Hospital and the Harvard Stem Cell Institute have discovered a possible source of the skin thickening that may be triggered by dysregulated stem cells.
Probiotics May Have an Impact on Psoriasis
December 14th 2019

Probiotics May Have an Impact on Psoriasis

Gianna Melillo
The link connecting gut bacteria and psoriasis is inflammation, the authors said.
Research Finds Sex Differences in Links Between Psoriasis and Metabolic Disorders
December 8th 2019

Research Finds Sex Differences in Links Between Psoriasis and Metabolic Disorders

AJMC Staff
There are significant sex differences in links between psoriasis and metabolic disorders, according to a study published this week.
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December 6th 2019

Abstract Recap: Cost-Effectiveness and Budget Impact of Tildrakizumab for First-Line Treatment of Plaque Psoriasis

Carrico J, Jia X, Zhao Y, et al. Cost-effectiveness, budget impact of tildrakizumab for the treatment of moderate to severe plaque psoriasis using 2019 drug costs [abstract L14]. J Manag Care Spec Pharm. 2019, 25(suppl 10-a):S79. doi: 10.18553/jmcp.2019.25.10-a.s1
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December 6th 2019

Abstract Recap: Real-World Treatment Patterns Among Patients With Moderate to Severe Plaque Psoriasis by Metabolic Syndrome Status

Feldman S, Zhang J, Martinez D, et al. Real-world treatment patterns of biologics, apremilast among patients with moderate to severe plaque psoriasis by metabolic syndrome status [abstract L11]. J Manag Care Spec Pharm. 2019, 25(suppl 10-a):S78. doi: 10.18553/jmcp.2019.25.10-a.s1.
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December 4th 2019

Abstract Recap: Trends in Costs and Healthcare Utilization Among Patients With Psoriasis and Psoriatic Arthritis

Prince P, Skornicki M, Suruki R, Lee E, Louder A. Economic burden of concomitant joint disease in psoriasis: a U.S.-linked claims, electronic medical records database analysis [abstract L7]. J Manag Care Spec Pharm. 2019, 25(suppl 10-a):S76. doi: 10.18553/jmcp.2019.25.10-a.s1.
Pair of Studies Explore Role of Key Proteins in Psoriasis
November 29th 2019

Pair of Studies Explore Role of Key Proteins in Psoriasis

Mary Caffrey
Two recent studies have explored the role of activator protein-1 (AP-1), a transcription factor with a role in skin diseases caused by inflammation, including psoriasis and atopic dermatitis
Development of PsA Linked to Tenosynovitis in Patients With Arthralgia
November 27th 2019

Development of PsA Linked to Tenosynovitis in Patients With Arthralgia

Allison Inserro
Researchers used ultrasound to investigate the anatomical basis for arthralgia symptoms and found that tenosynovitis was the only significant difference in patients who went on to develop psoriatic arthritis (PsA).
Patients With Psoriasis See Some Benefit From Disease Education
November 23rd 2019

Patients With Psoriasis See Some Benefit From Disease Education

Allison Inserro
Without information about the possible severity of their condition, patients with psoriasis may not adhere to treatment, which could lead to worse outcomes.
Topline Results Announced for Second Phase 3 Trial of Bimekizumab
November 21st 2019

Topline Results Announced for Second Phase 3 Trial of Bimekizumab

Mary Caffrey
BE READY is designed to evaluate the safety and efficacy of bimekizumab, humanized monoclonal IgG1 antibody that targets and neutralizes interleukin- (IL-)17A and IL-17F, a pair of cytokines that propel the inflammatory process through their effects on other messengers in the body that trigger chronic inflammatory response.
Age of Onset Determines Whether Psoriasis or Arthritis Develops First, Study Finds
November 16th 2019

Age of Onset Determines Whether Psoriasis or Arthritis Develops First, Study Finds

AJMC Staff
Genetics plays a strong role in the the trajectory of the how psoriatic arthritis manifests in joint arthritis compared with skin disease.
Providers Need to Heed Metabolic Syndrome's Complications for Women
November 15th 2019

Providers Need to Heed Metabolic Syndrome's Complications for Women

Allison Inserro
A recent study in the International Journal of Women’s Dermatology described the complex interplay of sex hormones in the pathways of metabolic syndrome (MetS) in pre- and postmenopausal women and how clinicians should be aware of the multiple factors of MetS.
Study Clarifies New Understandings About Timing of Psoriasis, Arthritis in Patients With PsA
November 10th 2019

Study Clarifies New Understandings About Timing of Psoriasis, Arthritis in Patients With PsA

Allison Inserro
The age of psoriasis onset determines whether arthritis or psoriasis starts first in patients with psoriatic arthritis (PsA).
Tildrakizumab More Cost-Effective Than Several Competitors in Treating Moderate to Severe Psoriasis
November 2nd 2019

Tildrakizumab More Cost-Effective Than Several Competitors in Treating Moderate to Severe Psoriasis

Mary Caffrey
Authors led by Justin Carrico of RTI Health Solutions compared 9 different biologics and the oral drug apremilast in treatment of psoriasis; their anaylsis, “from a US health plan’s perspective,” involved both base cost and cost-effectiveness models that included adverse events.
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October 30th 2019

Tildrakizumab in Patients With Psoriasis: Three-Year Efficacy Results From reSURFACE 1 and reSURFACE 2 in Those With and Without Metabolic Syndrome

Lebwohl MG, Leonardi C, Menter A, et al. Tildrakizumab efficacy by metabolic syndrome status in psoriasis: post hoc analysis of 3-year data from the phase 3 reSURFACE 1 study. Poster presented at: 28th European Academy of Dermatology Venereology Congress October 9-13, 2019 Madrid, Spain.Gottlieb AB, Leonardi C, Mehta NN, et al. Tildrakizumab efficacy by metabolic syndrome status in psoriasis: post hoc analysis of 3-year data from the phase 3 reSURFACE 2 study. Poster presented at: 28th European Academy of Dermatology and Venereology Congress Madrid, Spain.
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October 30th 2019

Four-Year Efficacy and Safety Outcomes From reSURFACE 1 and reSURFACE 2 in Patients Given Tildrakizumab for Plaque Psoriasis

Ida Delmendo
Crowley and colleagues presented the 4-year results from reSURFACE 1 at the 28th European Academy of Dermatology and Venereology Congress, held October 9-13, 2019 in Madrid, Spain.
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October 30th 2019

The Use of Realized Prices and Real-World Outcomes Data in Assessments of Drug Value

Meade D, Hensley AS. Impact of using real-world outcomes data versus clinical evidence published prices in value assessments. Presented at: ISPOR 2019 March 1-5 New Orleans, LA. Abstract PDG15.
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October 30th 2019

Productivity Loss and Indirect Costs Due to Psoriasis in the United States

Teeple A, Villacorta R, Lucas J. et al. An assessment of work-related productivity loss indirect costs for patients with psoriasis. Presented at: the 2019 Annual Meeting of the American Academy of Dermatology March 1-5 Washington, DC. Abstract 8319.
Treatment Landscape and Final Thoughts
October 22nd 2019

Treatment Landscape and Final Thoughts

Studies of Biologics on Cardiovascular Outcomes and Cost
October 22nd 2019

Studies of Biologics on Cardiovascular Outcomes and Cost

Understanding Plan B vs Plan D Coverage
October 22nd 2019

Understanding Plan B vs Plan D Coverage

Dosing Impact on Patient Adherence and Patient Preference
October 22nd 2019

Dosing Impact on Patient Adherence and Patient Preference

Improving Patient Adherence
October 22nd 2019

Improving Patient Adherence

IL-23: Long-term Data and Safety Data
October 22nd 2019

IL-23: Long-term Data and Safety Data

Decreased Efficacy, PASI Score vs BSA, and Nonresponders
October 22nd 2019

Decreased Efficacy, PASI Score vs BSA, and Nonresponders

Comorbidities and Changes in Treatment Plan
October 22nd 2019

Comorbidities and Changes in Treatment Plan

Patient Preferences and Payer Approval of Treatment
October 22nd 2019

Patient Preferences and Payer Approval of Treatment

Identifying the Differing Mechanisms of Available Biologics
October 22nd 2019

Identifying the Differing Mechanisms of Available Biologics

Standard of Care and Guidelines for Psoriasis
October 22nd 2019

Standard of Care and Guidelines for Psoriasis

Monitoring for Psoriasis Comorbidities and Associated Complications
October 22nd 2019

Monitoring for Psoriasis Comorbidities and Associated Complications

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