Migraine

The AJMC® Migraine compendium is a comprehensive resource for clinical news and expert insights for the recurring type of headache, which is accompanied by side effects.

Latest News

Prior Authorization Requirements for Calcitonin Gene-Related Peptide Antagonists

April 20th 2023

This quantitative and qualitative analysis highlights differences in prior authorization requirements for migraine drugs from nearly 50 managed care organizations and summarizes broad types of criteria used.

Image of a hurting perosn
Care for Migraine Insufficient in Germany, Online Survey Finds

March 25th 2022

woman with migraine
Comparing Benign Recurrent Vertigo With Vestibular Migraine, Menière's Disease

March 21st 2022

tech
Machine Learning Could Help Predict Migraineur Response to NSAIDs

March 17th 2022

people in hospital
Examining Trends in Headache-Related ED Visits, Treatment

March 14th 2022

Acute Migraine Treatment: Prevalence and Classes of Agents

Experts in the management of migraine discuss the prevalence of individuals taking acute migraine therapy and enumerate the various classes of agents available.

Acute and Preventive Therapy for Migraine peer exchange

More News

Healint, Novartis Use Self-Tracking App to Determine Prevalence of Anxiety, Depression in Migraine
September 7th 2018

Healint, Novartis Use Self-Tracking App to Determine Prevalence of Anxiety, Depression in Migraine

Jaime Rosenberg
Approximately 43% of patients using the Migraine Buddy app reported experiencing anxiety and/or depression during at least 1 migraine attack.
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August 31st 2018

Study Summary: Use of Estrogen-Containing Contraceptives Associated With Risk of Stroke Among Women With Migraine

Sheikh HU, Pavlovic, J, Loder E, Burch R. Risk of stroke associated with use of estrogen containing contraceptives in women with migraine: a systematic review. Headache. 2018, 58(1):5-21. doi: 10.111/head.13229.
Aggression Common in Chronic Migraine, May Help Identify Suicidality in Patients With Migraine
August 31st 2018

Aggression Common in Chronic Migraine, May Help Identify Suicidality in Patients With Migraine

Alison Rodriguez
Patient with chronic migraine were more likely to have aggression, anger, and hostility. Comorbid aggression may help to identify suicidality in migraine patients.
Fibromyalgia Worsens Depression, Pain Intensity in Migraine
August 29th 2018

Fibromyalgia Worsens Depression, Pain Intensity in Migraine

Jaime Rosenberg
Building on prior research drawing a link between migraine and fibromyalgia comorbidity, a new study has found that fibromyalgia exacerbates depressive symptoms, migraine intensity, and migraine-related disability.
Examining the Role of Sex Hormones in Migraine
August 25th 2018

Examining the Role of Sex Hormones in Migraine

Alison Rodriguez
A recent review evaluated current data on the effects of sex hormones on transient receptor potential channels, which contribute to the sensitization in migraine and chronic pain syndromes.
Having Migraine Puts Patients at Risk of Postsurgery Readmission
August 20th 2018

Having Migraine Puts Patients at Risk of Postsurgery Readmission

Jaime Rosenberg
Despite patients with migraine being younger and having fewer indicators for predicting readmission, they had an increased risk of 30-day hospital readmission due to pain.
Experts Assess Link Between Misclassification of Obesity and Prevalence of Migraine
August 17th 2018

Experts Assess Link Between Misclassification of Obesity and Prevalence of Migraine

Alison Rodriguez
The authors of a recent editorial explained that the higher prevalence of migraine in obese individuals may be due to a common etiological factor, because both conditions are linked to inflammatory processes.
PatientPoint, Migraine Again Partner to Bring Migraine Education to Practices Nationwide
August 13th 2018

PatientPoint, Migraine Again Partner to Bring Migraine Education to Practices Nationwide

Jaime Rosenberg
PatientPoint and Migraine Again have partnered to provide educational video content in nearly 5000 primary care and obstetrics/gynecology practices nationwide, offering patients and physicians insight into better managing migraine.
Study Investigates Association Between Migraine and Diabetes
August 10th 2018

Study Investigates Association Between Migraine and Diabetes

Alison Rodriguez
While the prevalence of migraine was significantly higher among patients with diabetes, the disease, itself, was not associated with a greater risk of migraine.
Migraine Survey Highlights Significant Lack of Awareness of CGRP Inhibitors
August 9th 2018

Migraine Survey Highlights Significant Lack of Awareness of CGRP Inhibitors

Jaime Rosenberg
Just one-third of respondents of the Migraine in America 2018 survey, conducted by Health Union, are aware of calcitonin gene-related peptide (CGRP) inhibitors. Those who did know about the therapies had questions and concerns, such as cost, insurance coverage, and side effects.
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August 9th 2018

Efficacy and Safety of Erenumab in Patients with Chronic Migraine Who Have Experienced Preventive Treatment Failure

Ashina M, Tepper S, Brandes JL, et al. Efficacy safety of erenumab (AMG334) in chronic migraine patients with prior preventive treatment failure: a subgroup analysis of a randomized, double-blind, placebo-controlled study [published online January 1, 2018]. Cephalalgia. doi: 10.1177/0333102418788347.
CGRP Inhibitor Erenumab Gains EU Approval for Migraine Prevention
August 2nd 2018

CGRP Inhibitor Erenumab Gains EU Approval for Migraine Prevention

Jaime Rosenberg
The once-monthly self-injected calcitonin gene-related peptide (CGRP) inhibitor is now approved in the European Union, Switzerland, the United States, and Australia.
Poor Sleep Quality Prevalent Among Patients with Probable Migraine, Study Finds
August 1st 2018

Poor Sleep Quality Prevalent Among Patients with Probable Migraine, Study Finds

Alison Rodriguez
Previous research has revealed that poor sleep quality is common among those with migraine. New study results point to similar findings for those with probable migraine—a subtype of migraine that is common in the general population.
Chronic Migraine Linked to Lower Visual Quality of Life
July 27th 2018

Chronic Migraine Linked to Lower Visual Quality of Life

Jaime Rosenberg
Researchers found that people who suffer from chronic migraine experience visual quality of life impacts comparable to other neoro-opthalmic disorders.
Study Suggests Integrating Migraine and Depression Treatment
July 25th 2018

Study Suggests Integrating Migraine and Depression Treatment

Alison Rodriguez
A recent study investigated the associations of migraine with pain symptoms among outpatients with major depressive disorder during a 10-year period, finding that migraine treatment should be integrated into treatment for depression to improve patients’ pain symptoms and health-related quality of life.
History of Migraine Linked to Development of Tinnitus, Other Cochlear Disorders
July 21st 2018

History of Migraine Linked to Development of Tinnitus, Other Cochlear Disorders

Jaime Rosenberg
Researchers observed that migraine was associated with an increased risk of developing a cochlear disorder, especially tinnitus.
The Prevalence of Coprescribing an Opioid With Serotonergic Antidepressant to Treat Migraine
July 19th 2018

The Prevalence of Coprescribing an Opioid With Serotonergic Antidepressant to Treat Migraine

Alison Rodriguez
Recent data shows how common combination coprescribing of opioids with a triptan or a serotonergic antidepressant was just 2 years prior to an FDA warning about the risk of serotonin syndrome from such coprescribing.
ICER Releases Final Evidence Report on Efficacy, Cost Effectiveness of CGRP Inhibitors for Migraine
July 14th 2018

ICER Releases Final Evidence Report on Efficacy, Cost Effectiveness of CGRP Inhibitors for Migraine

Alison Rodriguez
The Institute for Clinical and Economic Review (ICER) has released their final evidence report evaluating the effectiveness and value of calcitonin gene-related peptide (CGRP) inhibitors as preventive treatments for patients who suffer from episodic or chronic migraine.
Utilizing Mobile Health Technology to Improve Migraine Care
July 13th 2018

Utilizing Mobile Health Technology to Improve Migraine Care

Jaime Rosenberg
Through a smartphone app, SensorRx is utilizing patient-collected data and linking it to the patient’s electronic health record, allowing the physician to better understand a patient’s migraine trends and improve outcomes.
Coffee and Chocolate Most Common Dietary Triggers for Migraine
July 4th 2018

Coffee and Chocolate Most Common Dietary Triggers for Migraine

Alison Rodriguez
As researchers examined what food and drinks were most commonly linked to migraine and tension-type headache in Malaysian patients, they found that coffee and chocolate were reported most often.
Amgen, Novartis Announce Positive Long-Term Efficacy and Safety Data of Erenumab for Migraine
July 2nd 2018

Amgen, Novartis Announce Positive Long-Term Efficacy and Safety Data of Erenumab for Migraine

Jaime Rosenberg
According to Amgen and Novartis, their calcitonin gene-related peptide inhibitor has demonstrated safety and efficacy in a 1-year study in chronic migraine and reinforced safety and tolerability in a 3-year interim analysis from an ongoing 5-year study in episodic migraine.
Increased Estrogen Levels Associated With Migraine in Men
June 28th 2018

Increased Estrogen Levels Associated With Migraine in Men

Jaime Rosenberg
While it is known that heightened estrogen levels are linked to an increased prevalence of migraine in women, new research suggests that the hormone plays an equally important role in causing migraine among men.
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June 28th 2018

Study Summary: Pilot test of a Mobile App to Improve Treatment Adherence in Young Patients With Migraine

Ramsey RR, Holbein CE, Powers SW, et al. A pilot investigation of a mobile phone application progressive reminder system to improve adherence to daily prevention treatment in adolescents and young adults with migraine [published online January 3, 2018]. Cephalalgia. doi: 10.1177/0333102418756864.
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June 28th 2018

Study Summary: Link Between Migraine and Suicidal Behaviors

Friedman LE, Zhong QY, Gelaye B, Williams MA, Peterlin BL. Association between migraine, suicidal behaviors: a nationwide study in the USA. Headache. 2018, 58(3):371-380. doi: 10.1111/head.13235.
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June 28th 2018

Study Summary: Links Among Depression, Anxiety, and Headache Frequency in Patients With Migraine

Chu HT, Liang CS, Lee JT, et al. Associations between depression/anxiety, headache frequency in migraineurs: a cross-sectional study. Headache. 2018, 58(3):407-415. doi: 10.1111/head.13215.
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June 27th 2018

Study Summary: Greater Occipital Nerve Block for Acute Migraine Treatment

Allen SM, Mookadam F, Cha SS, Freeman JA, Starling AJ, Mookadam M. Greater occipital nerve block for acute treatment of migraine headache: a large retrospective cohort study. J Am Board Fam Med. 2018, 31(2):211-218. doi: 10.3122/jabfm.2018.02.170188.
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June 27th 2018

Study Summary: Vestibular Symptoms Related to Disability in Patients With Migraine

Carvalho GF, Vianna-Bell FH, Florencio LL, et al. Presence of vestibular symptoms related disability in migraine with and without aura and chronic migraine [published online January 1, 2018]. Cephalalgia. doi: 10.1177/0333102418769948.
Study Assesses Association Between Migraine and Allergies in Children
June 26th 2018

Study Assesses Association Between Migraine and Allergies in Children

Alison Rodriguez
The average duration of a migraine was found to be independent from the presence of allergy, as well as the frequency of the cephalalgy attacks, and the localization of the pain.
Study Compares Cannabis Benefits for Patients With Chronic Pain and Migraine
June 22nd 2018

Study Compares Cannabis Benefits for Patients With Chronic Pain and Migraine

Alison Rodriguez
For many patients with migraine, cannabis served as a substitute for other pain medications, including opioids.
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June 19th 2018

Study Summary: Estimating the Value-Based Price Range of Erenumab for Migraine Prevention

Lipton RB, Brennan A, Palmer S, et al. Estimating the clinical effectiveness value-based price range of erenumab for the prevention of migraine in patients with prior treatment failures: a US societal perspective. [published online April 3, 2018]. J Med Econ. doi: 10.1080/13696998.2018.1457533.
This health economic analysis predicted that, compared with use of supportive care, erenumab treatment will reduce the direct and indirect costs associated with migraine and increase quality-adjusted life-years for patients who have previously experienced treatment failure with at least 1 preventive migraine treatment.
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