Migraine

The AJMC^® Migraine compendium is a comprehensive resource for clinical news and expert insights for the recurring type of headache, which is accompanied by side effects.

Latest News

Prior Authorization Requirements for Calcitonin Gene-Related Peptide Antagonists

By Lindsay Musial, PharmD
Steven Kheloussi, PharmD, MBA

April 20th 2023

This quantitative and qualitative analysis highlights differences in prior authorization requirements for migraine drugs from nearly 50 managed care organizations and summarizes broad types of criteria used.

Image of a hurting perosn

Care for Migraine Insufficient in Germany, Online Survey Finds

By Maggie L. Shaw

March 25th 2022

woman with migraine

Comparing Benign Recurrent Vertigo With Vestibular Migraine, Menière's Disease

By Gianna Melillo

March 21st 2022

tech

Machine Learning Could Help Predict Migraineur Response to NSAIDs

By Gianna Melillo

March 17th 2022

people in hospital

Examining Trends in Headache-Related ED Visits, Treatment

By Gianna Melillo

March 14th 2022

Acute Migraine Treatment: Prevalence and Classes of Agents

Experts in the management of migraine discuss the prevalence of individuals taking acute migraine therapy and enumerate the various classes of agents available.

Acute and Preventive Therapy for Migraine peer exchange

More News

MRIs Find Abnormalities in Central Vestibular Cortex of Some Patients With Migraine

March 17th 2020

MRIs Find Abnormalities in Central Vestibular Cortex of Some Patients With Migraine

Magnetic resonance imaging (MRI) scans of patients with vestibular migraine reveal abnormalities in the central vestibular cortex, according to a study published in Brain and Behavior.

Family History of Migraine Linked to Earlier Age of Onset, Study Says

March 15th 2020

Family History of Migraine Linked to Earlier Age of Onset, Study Says

Alison Rodriguez

Family history with migraine affect male and female patients differently, according to a recent study.

Report Finds Natural Clusters of Chronic Migraine Phenotypes

March 10th 2020

Report Finds Natural Clusters of Chronic Migraine Phenotypes

Researchers were able to use questionnaire responses to accurately determine natural clusters of chronic migraine phenotypes, according to a study published in Scientific Reports.

Review Assesses Role of Vitamin D in Migraine Mechanism, Treatment

March 7th 2020

Review Assesses Role of Vitamin D in Migraine Mechanism, Treatment

Eighteen out of 30 studies included in a recent literature review, published in Nutrients, showed a link between serum vitamin D levels and headaches, with the strongest connection established between serum vitamin D and migraine.

Chocolate Lover? Review Finds No Definitive Proof It Triggers Your Migraines

March 5th 2020

Chocolate Lover? Review Finds No Definitive Proof It Triggers Your Migraines

Although it is the most commonly cited food-based trigger for migraines, there is insufficient evidence to prove chocolate is a migraine trigger, according to a review of 25 studies published in Nutrients.

ICER Releases Final Evidence Report on Acute Treatments for Migraine

February 27th 2020

ICER Releases Final Evidence Report on Acute Treatments for Migraine

The Institute for Clinical and Economic Review (ICER) released its final evidence report on acute treatments of migraine on February 25. The Institute’s last report on migraine treatment was released in 2018.

Review Outlines Relationship Between Gut-Brain Axis, Migraine

February 25th 2020

Review Outlines Relationship Between Gut-Brain Axis, Migraine

The association between migraine and several gastrointestinal (GI) disorders prompted investigations into the bidirectional relationship between the GI system and central nervous system. Researchers call this association the “gut-brain axis,” and they evaluated direct and indirect evidence linking migraines to the axis in a recent review published in The Journal of Headache and Pain.

Study Suggests 5 Stroke Risk Factors for Those With Migraine, Aura

February 22nd 2020

Study Suggests 5 Stroke Risk Factors for Those With Migraine, Aura

Alison Rodriguez

The research revealed 5 risk factors for stroke for patients with migraine with aura.

Migraineurs Exhibit Unique Sensory Responses to Stimuli

February 19th 2020

Migraineurs Exhibit Unique Sensory Responses to Stimuli

Researchers determined that migraineurs exhibit unique responses to tactile stimuli compared with controls, according to a study published in Cephalalgia.

February 18th 2020

Concomitant Medical Conditions and Total Cost of Care in Patients With Migraine: A Real-World Claims Analysis

Michael Polson, PharmD, MS Ted D. Williams, PharmD, BCPS Lindsay C. Speicher, JD Mkaya Mwamburi, MD, PhD, MA Peter S. Staats, MD, MBA Andrew T. Tenaglia, BA

February 18th 2020

Real-World Assessment of Concomitant Opioid Utilization and Associated Trends in Patients With Migraine

Anne Kangethe, PharmD, PhD, RPh, MPH Michael Polson, PharmD, MS Themmi M. Evangelatos, PharmD, MSBA Lindsay C. Speicher, JD Andrew T. Tenaglia, BA Peter S. Staats, MD, MBA Eric J. Liebler Mkaya Mwamburi, MD, PhD, MA

February 18th 2020

Patient Experience With Non-Invasive Vagus Nerve Stimulator: gammaCore Patient Registry

Mkaya Mwamburi, MD, PhD, MA Eric J. Liebler Peter S. Staats, MD, MBA

Evidence Links Migraine and Visual Cortex Abnormalities

February 12th 2020

Evidence Links Migraine and Visual Cortex Abnormalities

Those who suffer from migraines have a hyperexcitable visual cortex, according to a study published in Neuroimage: Clinical. This is the first reported evidence establishing a link between migraine experiences and abnormalities in the visual cortex.

Researchers Outline Lessons Learned About Chronic Migraine Gleaned From Neuroimaging

February 9th 2020

Researchers Outline Lessons Learned About Chronic Migraine Gleaned From Neuroimaging

Alison Rodriguez

Where do migraines begin in the brain and what has neuroimaging identified so far about how the disease alters pain processes and functioning? A recent article reviewed what is known so far.

Migraineurs Exhibit Comorbidities Spanning ICD-10 Spectrum

February 4th 2020

Migraineurs Exhibit Comorbidities Spanning ICD-10 Spectrum

Electronic medical record data showed migraine is associated with a systematic increase in morbidity across the spectrum of the International Classification of Diseases, Tenth Revision (ICD-10), according to a recently published study in The Journal of Headache and Pain.

Reduction of Prolactin Associated With Pain Relief, Headache Study Finds

February 1st 2020

Reduction of Prolactin Associated With Pain Relief, Headache Study Finds

Alison Rodriguez

Migraine was the most common type of headache in patients with hyperprolactinemia.

Chronic Pain in Migraine May Be Mitigated by Craniosacral Therapy

January 25th 2020

Chronic Pain in Migraine May Be Mitigated by Craniosacral Therapy

Sara Karlovitch

The literature review examined randomized controlled trials for craniosacral therapy (CST) in patients with migraine and other conditions that cause pain.

Use of ICHD-3 Increases Specificity When Diagnosing Migraine With Aura and Typical Aura

January 22nd 2020

Use of ICHD-3 Increases Specificity When Diagnosing Migraine With Aura and Typical Aura

Researchers determined that new diagnostic criteria in the International Classification of Headache Disorders, 3rd edition (ICHD-3) are significantly more specific than that included in ICHD-3 beta when it comes to diagnosing migraine with aura and with typical aura, according to a study published in The Journal of Headache and Pain.

Evidence Shows Genetic, Epigenetic Factors May Be Responsible for Migraine Transformation

January 18th 2020

Evidence Shows Genetic, Epigenetic Factors May Be Responsible for Migraine Transformation

Sara Karlovitch

Individuals’ susceptibility to genetic and epigenetic factors may be responsible for the transformation of episodic migraine to chronic migraine in some patients, according to a new review published in The Journal of Headache and Pain.

Data Reveal Predictors of Transformation From Episodic to Chronic Migraine

January 15th 2020

Data Reveal Predictors of Transformation From Episodic to Chronic Migraine

A systematic review and meta-analysis of data collected from observational cohort studies reveals several clinical and sociodemographic factors are predictors of chronic migraine.

Current Stimulation to Occipital Cortex Effective in Treating Episodic Migraine

January 7th 2020

Current Stimulation to Occipital Cortex Effective in Treating Episodic Migraine

In a study published December 26 in the Journal of Clinical Medicine, researchers tested the effects of cathodal transcranial direct current stimulation in the occipital cortex of 42 patients with episodic migraine.

AJMC® in the Press, January 3, 2020

January 3rd 2020

AJMC® in the Press, January 3, 2020

Coverage of our peer-reviewed research and news reporting in the healthcare and mainstream press.

Italian Study Finds Cost of Migraine Treatment Higher for Women, Elderly

January 2nd 2020

Italian Study Finds Cost of Migraine Treatment Higher for Women, Elderly

In a recently published study in The Journal of Headache and Pain, Italian researchers compiled data on 548 patients suffering from chronic and episodic migraines enrolled in a tertiary level headache center to determine overall costs incurred.

Review Finds Studies on Migraine and Caffeine Association Inconclusive

December 27th 2019

Review Finds Studies on Migraine and Caffeine Association Inconclusive

In a narrative review published in Frontiers in Neurology, researchers compiled evidence from various studies on the relationship between caffeine and migraines. From the data collected, researchers concluded that the relationship between them remains vague.

Greek Researchers Outline New Consensus on Diagnosis and Treatment of Migraine

December 19th 2019

Greek Researchers Outline New Consensus on Diagnosis and Treatment of Migraine

On behalf of the Hellenic Headache Society, a group of Greek researchers reported a consensus on the diagnosis and treatment of adult migraines in The Journal of Headache and Pain on December 13.

Low Sleep Efficiency Associated With Higher Odds of Migraine, Study Shows

December 18th 2019

Low Sleep Efficiency Associated With Higher Odds of Migraine, Study Shows

Matthew Gavidia

Sleep fragmentation, which is defined by low sleep efficiency, was linked with higher odds of migraine onset on day 1, according to study findings published this week.

Study Finds Bidirectional Relationship Between Asthma, Migraines

December 13th 2019

Study Finds Bidirectional Relationship Between Asthma, Migraines

Migraines increase the risk of asthma, and asthma is also associated with an elevated risk of migraine, according to new research.

Researchers Uncover Effectiveness of 2 Preventive Agents in Reducing Incidence, Severity of Pediatric Migraine

December 11th 2019

Researchers Uncover Effectiveness of 2 Preventive Agents in Reducing Incidence, Severity of Pediatric Migraine

Matthew Gavidia

Two migraine prevention agents, cinnarizine and sodium valproate, were shown to be safe and effective in reducing incidence and severity of migraine within children and adolescents, according to study findings. Safety findings must be weighed alongside warnings from European regulators about the risks of valproate for girls and adolescent women who could bear children in the future.

Epigenetic Diet for Migraine Requires More Research, Review Finds

December 9th 2019

Epigenetic Diet for Migraine Requires More Research, Review Finds

Alison Rodriguez

The epigenetic diet is often recommended for patient with migraine; however, the diet does not necessarily affect the epigenetic profile, suggesting the need for more research investigating the combined effect of folate and valproic acid in migraine in order to determine dietary recommendations.

Acupuncture for Migraine May Have Some Benefits but Quality of Studies Lacking, Report Says

December 5th 2019

Acupuncture for Migraine May Have Some Benefits but Quality of Studies Lacking, Report Says

The studies did not disclose whether acupuncture was utilized to ease acute attacks or the overall condition, calling into question the significance of collected data.

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