Immunology

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Methotrexate box | Image credit: DenisMArt – stock.adobe.com
Methotrexate May Lower Blood Pressure in Rheumatoid Arthritis

September 4th 2025

Methotrexate significantly lowered systolic blood pressure compared with sulfasalazine in adults with newly diagnosed rheumatoid arthritis, suggesting potential cardiovascular benefits beyond its anti-inflammatory effects.

Hand holding smoking cigarette | Image credit: methaphum – stock.adobe.com
Smoking Remains a Major Driver of Rheumatoid Arthritis Burden Worldwide

August 30th 2025

Older couple outside holding their hands to their hearts | Image credit: EFStock – stock.adobe.com
Rheumatoid Arthritis Linked to Elevated Risk of Degenerative Valvular Heart Disease

August 28th 2025

Doctor administering vaccine to older woman | Image credit: Halfpoint – stock.adobe.com
Shingles Vaccine Generates Strong Immune Response in Patients With RA Receiving Upadacitinib

August 28th 2025

Older adult holding several pills and glass of water | Image credit: Kotchakorn – stock.adobe.com
Polypharmacy Common in Rheumatoid Arthritis, Driving Risk of Serious Drug Interactions

August 13th 2025

More News

hidradenitis suppurativa | Image Credit: Yurii Kibalnik-stock.adobe.com
November 14th 2024

Underdiagnosis of Hidradenitis Suppurativa May Link to Socioeconomic Factors

Maggie L. Shaw
Investigators were seeking a greater understanding of risk factors for hidradenitis suppurativa, a chronic inflammatory skin disease, concentrating on how it presents in skin of color.
Hidradenitis suppurativa | Image Credit: © syahrir-stock.adobe.com
November 11th 2024

Possible Genetic Links Between Hidradenitis Suppurativa and CAD, Diabetes Risks

Maggie L. Shaw
In this study, investigators were seeking to uncover potential genetic correlations between hidradenitis suppurativa and downstream risk of cardiometabolic disease, such as coronary artery disease (CAD) and diabetes, in older adults.
Itchy pregnant belly | Image Credit: © chajamp stock.adobe.com
October 31st 2024

With Hidradenitis Suppurativa, Maternal and Offspring Outcomes May Suffer

Gayle Turim Dickstein
Novel evidence has emerged from a 16-year study that hidradenitis suppurativa can elevate risks of not only pregnancy and postpartum complications, but of morbidity—particularly metabolic- and immunology-related morbidity—for mother and child in the long term.
Bacteria in the gut | Image Credit: © Julien Tromeur-stock.adobe.com
October 25th 2024

Gut Bacteria Tied to Ankylosing Spondylitis Severity

Maggie L. Shaw
These authors investigated the potential influence of gut microbiota on ankylosing spondylitis pathophysiology.
Amit Garg, MD, Northwell Health
October 18th 2024

Bimekizumab Poised to Tackle Unmet HS Treatment Needs

Maggie L. Shaw
Hidradenitis suppurativa (HS) is an inflammatory, chronic disease with very high symptom and physical burdens, and it can get progressively worse over time if it's inadequately treated, explained Amit Garg, MD, founding chair, Department of Dermatology, Northwell Health.
psoriasis on a white man | Image credit: fusssergei - stock.adobe.com
October 14th 2024

Navigating Racial Disparities in Psoriatic Arthritis: Insights From Patient-Reported Outcomes

Skylar Jeremias
Individuals with self-reported moderate to severe psoriatic arthritis (PsA) face a higher disease burden, particularly among Black participants, highlighting the need for a better understanding of the interplay between PsA severity and racial and ethnic disparities.
Infertility concept | Image Credit: © andriano_cz-stock.adobe.com
October 4th 2024

Infertility Not Linked to Hidradenitis Suppurativa

Maggie L. Shaw
Previous research has linked hidradenitis suppurativa to infertility, but concrete data are lacking on causality of the chronic inflammatory skin condition in this setting.
FDA approved | Image credit: wladimir1804 - stock.adobe.com
September 23rd 2024

FDA Approves Bimekizumab for Psoriatic Arthritis, Nonradiographic AxSpA, Ankylosing Spondylitis

Rose McNulty
Bimekizumab-bkzx (Bimzelx) is now FDA approved for 4 chronic immune-mediated inflammatory diseases: psoriatic arthritis, nonradiographic axial spondyloarthritis (axSpA), ankylosing spondylitis, and moderate to severe plaque psoriasis.
Back pain due to axial spondyloarthritis | Image credit: Lila Patel - stock.adobe.com
September 23rd 2024

Patients With AxSpA Have Complex Needs, Require Tailored Treatment

Rose McNulty
New findings add to the understanding of the patient experience in axial spondyloarthritis (axSpA), which can help inform patient-centered clinical care.
FDA-ra2studio-stock.adobe.com.jpeg
September 18th 2024

FDA Approves Benralizumab for Eosinophilic Granulomatosis With Polyangiitis

Pearl Steinzor
The FDA approved benralizumab (Fasenra) for adult patients with eosinophilic granulomatosis with polyangiitis (EGPA).
Image credit: Елена Бутусова - stock.adobe.com
September 13th 2024

Higher Risk of ILD in Patients With RA, PsA Initiating bDMARDs

Victoria Johnson
There were no differences in risk between patients with RA or PsA using or not using methotrexate.
The model’s predictions were in line with established cell distributions within each phenotype of rheumatoid arthritis. | Image credit: ArtemisDiana - stock.adobe.com
September 6th 2024

Machine Learning Effectively Characterizes Rheumatoid Arthritis Subtypes

Victoria Johnson
Investigators noted that a formal independent validation cohort needs to be developed to realize the full potential of the human model.
Bimekizumab showed sustained, consistent effectiveness to 52 weeks with or without methotrexate in psoriatic arthritis. | Image credit: stockdevil - stock.adobe.com
August 22nd 2024

Bimekizumab Shows Persistent Efficacy, Safety in Psoriatic Arthritis at 52 Weeks

Rose McNulty
Treatment with bimekizumab showed consistent efficacy through 52 weeks in patients with psoriatic arthritis in a post hoc analysis of the BE OPTIMAL, BE COMPLETE, and BE VITAL trials.
Findings suggest checking regular radiographs in clinical practice for loss of bone density or VFs can be helpful in managing axial spondyloarthritis. - Mutshino_Artwork - stock.adobe.com
August 16th 2024

Long-Term TNFi Treatment for AxSpA Improved, Maintained Bone Mineral Density

Rose McNulty
Lumbar spine bone mineral density improved significantly and was maintained during long-term tumor necrosis factor inhibitor (TNFi) treatment for axial spondyloarthritis.
AJMC
August 15th 2024

Geographic Variability of Medicaid Acceptance Among Allergists in the US

Frances O. Ho, MD Chaoyi Zheng, MS Mech Frazier, MA Sai R. Nimmagadda, MD Ruchi S. Gupta, MD, MPH Lucy A. Bilaver, PhD
The proportion of allergists accepting Medicaid in the US varied significantly among and within states.
Disease control was linked with better quality of life among patients with psoriatic arthritis. | Image credit: Evrymmnt - stock.adobe.com
August 9th 2024

Clinical Disease Control in Psoriatic Arthritis Improves Quality of Life

Lana Pine
Responders at week 104 demonstrated more significant changes from baseline and achieved normative values in PROs compared with non-responders.
Rheumatoid arthritis | Image: LinkedIn
August 5th 2024

Understanding Inflammatory Pathways to Address CV Risk in Patients With Autoimmune Disease

Mary Caffrey
A session on the final day of the 2024 Congress of the American Society of Preventive Cardiology explored the connections between autoimmune disease and cardiac events.
In the pooled analysis, ankylosing spondylitis was associated with a greater risk of cancer occurrence. | Image credit: Lila Patel - stock.adobe.com
July 26th 2024

Meta-Analysis Finds Link Between Ankylosing Spondylitis, Cancer Risk

Rose McNulty
The authors of the new meta-analysis aimed to provide an update on the association between ankylosing spondylitis and cancer incidence.
myasthenia gravis | Image Credit: Николай Зотов-stock.adobe.com
July 21st 2024

Chinese Patients With gMG Respond Well to Efgartigimod

Jared Kaltwasser
A new report offers safety and efficacy data on a population with generalized myasthenia gravis (gMG) not represented in the drug’s pivotal phase 3 trial.
Arthritis in hands - stockdevil - stock.adobe.com
July 20th 2024

Persistently Active Rheumatoid Arthritis Linked With Socioeconomic Factors

Lana Pine
Factors independently associated with persistently active RA included age, gender, previous or current smoking status, and social deprivation.
The review identified several challenges to quality rheumatoid arthritis treatment, along with potential interventions to improve care. | Image Credit: MicroOne - stock.adobe.com
July 18th 2024

Gaps in Rheumatoid Arthritis Care Quality Exist in North America

Rose McNulty
A literature review plus in-person visits helped identify barriers to quality rheumatoid arthritis care, as well as effective interventions to improve care quality.
Book about myasthenia gravis | Image Credit: mdaros-stock.adobe.com
July 16th 2024

Promising Results for Efgartigimod in Myasthenic Crisis

Kimberly Rath, PharmD
A new case report details the successful use of efgartigimod as a rescue medication in a patient with therapy-refractory myasthenic crisis.
Physical therapy on treadmill | Image credit: Justlight - stock.adobe.com
July 9th 2024

Exercise Therapy Can Reduce Symptoms, Disease Activity in Axial Spondyloarthritis

Rose McNulty
Patients with axial spondyloarthritis who took part in exercise therapy showed improvements in disease activity and symptoms compared with patients who did not, a meta-analysis found.
Patient rubbing sore hands with rheumatoid arthritis | Image credit: Evrymmnt - stock.adobe.com
July 3rd 2024

Patient-Reported Pain Improvement Linked With Remission in Rheumatoid Arthritis

Rose McNulty
Pain improvement was associated with remission or low disease activity in patients undergoing treatment for rheumatoid arthritis, a study found.
Obesity was linked with worse patient-reported pain outcomes in rheumatoid arthritis. | Image credit: 9nong - stock.adobe.com
July 1st 2024

Obesity Linked to Worse Patient-Reported Outcomes in Rheumatoid Arthritis

Abigail Brooks, MA
Patients with rheumatoid arthritis and obesity exhibited worse scores for subjective measures like pain and fatigue compared with those without obesity.
Spine MRI - Kondor83 - stock.adobe.com
June 29th 2024

Preexisting Structural Damage, Inflammation Linked With Radiographic Progression in Patients Treated for AxSpA

Rose McNulty
Preexisting spinal damage and higher levels of inflammatory activity at baseline were linked with radiographic progression in axial spondyloarthritis treated with biologic disease-modifying antirheumatic drugs over 2 years regardless of treatment type.
Bimekizumab demonstrated safety and efficacy at 2 years among patients with nr-axSpA and AS. - natali_mis - stock.adobe.com
June 28th 2024

Bimekizumab Shows Long-Term Efficacy in Nonradiographic AxSpA, Ankylosing Spondylitis

Rose McNulty
Bimekizumab demonstrated safety and efficacy at 2 years among patients with nonradiographic axial spondyloarthritis (nr-axSpA) and ankylosing spondylitis (AS).
Back pain due to spondyloarthritis- fizkes - stock.adobe.com
June 22nd 2024

AxSpA Treatment Intensification in Practice Linked With Higher ASDAS Cutoff Than Recommended

Rose McNulty
In the clinical practice setting, intensifying treatment for axial spondyloarthritis (axSpA) is associated with a higher Ankylosing Spondylitis Disease Activity Score (ASDAS) cutoff value than recommended, new research found.
Efgartigimod alfa and hyaluronidase is now FDA approved for the treatment of adults with CIDP. | Image credit: wladimir1804 - stock.adobe.com
June 21st 2024

FDA Approves Efgartigimod Alfa and Hyaluronidase for CIDP

Rose McNulty
The FDA today approved efgartigimod alfa and hyaluronidase-qvfc for the treatment of adult patients with chronic inflammatory demyelinating polyneuropathy (CIDP).
Sarilumab FDA Approved for Active Polyarticular Juvenile Idiopathic Arthritis
June 11th 2024

Sarilumab FDA Approved for Active Polyarticular Juvenile Idiopathic Arthritis

Rose McNulty
The approval brings a new treatment option to pediatric patients with polyarticular juvenile idiopathic arthritis, which is a form of arthritis affecting multiple joints at the same time.
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