HIV

The AJMC^® HIV compendium is a comprehensive resource for clinical news and expert insights for the condition, including disparities in care, prevention of infection among at-risk groups, and the importance of viral suppression.

Latest News

Vaccination | Image credit: Prostock-studio - stock.adobe.com

HPV Vaccination Cost-Effective at Preventing Cervical Cancer in Patients With HIV

By Julia Bonavitacola

November 21st 2024

Women living with HIV can reduce their risk of cervical cancer using a human papillomavirus (HPV) vaccine that is both cost-effective and effective in preventing the virus.

HIV | Image credit: Corona Borealis - stock.adobe.com

New Data Provide Clearer Picture on Adherence to Lenacapavir

By Julia Bonavitacola

November 18th 2024

HIV | Image credit: RAJCREATIONZS - stock.adobe.com

BIC/FTC/TAF Effective at Virologic Suppression in HIV Presenting Late

By Julia Bonavitacola

November 15th 2024

Liver | Image credit: PIC4U - stock.adobe.com

Liver Steatosis, Fibrosis Highly Prevalent in People Living With HIV

By Julia Bonavitacola

November 12th 2024

Madalitso Juwayeyi

Empowering Young Women in the Fight Against HIV

By Maggie L. Shaw

November 8th 2024

Clarifying USPSTF Recommendations for HIV Pre-Exposure Prophylaxis (PrEP)

This discussion focuses on how to address barriers and disparities as obstacles to using PrEP, with a focus on USPSTF PrEP guidelines and ACA Part 47 for payers and providers.

This multi-stakeholder roundtable panel discussion will focus on how to address barriers and disparities as obstacles to the use of PrEP, with a focus on increased understanding and education around US Preventive Services Task Force (USPSTF) PrEP guidelines and Affordable Care Act Part 47 for payers and providers.

Continuing Medical Education

November 21st 2024

Navigating the HIV Treatment Frontier: Equipping Managed Care Professionals With Strategies for Innovation, Access, and Adherence

1.5 Credits / HIV/AIDS, Infectious Diseases

More News

Antibody "Cocktail" Could Offer Potent Treatment, Prevention of COVID-19

July 23rd 2020

Antibody "Cocktail" Could Offer Potent Treatment, Prevention of COVID-19

Writing in Nature, scientists found the antibodies fell into 2 distinct groups, targeting different regions of the viral spike. Thus, they say, the battle against coronavirus disease 2019 (COVID-19) could be opened on separate fronts, much like the approach Ho and others have studied in HIV and some forms of cancer.

Treatment Adherence, Viral Suppression Suffer Due to HIV-Related Stigma in Florida

July 22nd 2020

Treatment Adherence, Viral Suppression Suffer Due to HIV-Related Stigma in Florida

Stigma perpetuated in a health care setting has been linked to greater odds of poor outcomes in the HIV continuum of care for antiretroviral treatment adherence and reduced viral suppression among persons living with HIV in Florida.

A Computer-Simulation Model Attempts to Reframe Costs, Solutions to Ending HIV in the United States

July 16th 2020

A Computer-Simulation Model Attempts to Reframe Costs, Solutions to Ending HIV in the United States

To effectively end the HIV epidemic in the United States, combination strategies should be tailored according to need, backed by evidence-based interventions, and scaled according to location, report study results in The Lancet HIV.

PrEP Use Has Changed Following Implementation of Social Distancing Measures

July 13th 2020

PrEP Use Has Changed Following Implementation of Social Distancing Measures

A pair of late-breaking abstracts presented during AIDS 2020, this year’s virtual meeting of the International AIDS Society, detailed the effects that the coronavirus disease 2019 pandemic has had on trends in at-risk sexual behaviors and pre-exposure prophylaxis (PrEP) use, both in the United States and in Australia, due to shelter-in-place orders and social distancing.

July 13th 2020

Having a Consistent HIV Health Care Provider and HIV-Related Clinical Outcomes

Zhi Wang, PhD Hsien-Chang Lin, PhD

The study examined the association of having a consistent HIV health care provider with related clinical outcomes, with an emphasis on a long-term physician-patient relationship.

Donor Government Funding for HIV Falls

July 9th 2020

Donor Government Funding for HIV Falls

A recent analysis conducted by the Kaiser Family Foundation and The Joint United Nations Program on HIV/AIDS found donor governments spent $7.8 billion for HIV in 2019, a decrease of $165 million from the previous year. This number is similar to that spent a decade ago, despite a 25% increase of individuals now living with HIV in regions receiving the aid.

FDA Approves HIV Drug for Adults With Multidrug-Resistant Infection

July 7th 2020

FDA Approves HIV Drug for Adults With Multidrug-Resistant Infection

Laura Joszt, MA

Patients with HIV who have been heavily treated but are failing their current regimen have few treatment options and are at risk of progressing to AIDS and death.

Study Identifies Possible New Patient Phenotype in HIV Space

July 4th 2020

Study Identifies Possible New Patient Phenotype in HIV Space

Previously associated with elite controller status, having an inherent low viral reservoir is now possibly linked to individuals with chronic HIV infection who initiate treatment with antiretrovirals more than 6 months after becoming infected.

Top 5 Most-Read News Stories During the First Half of 2020

July 3rd 2020

Top 5 Most-Read News Stories During the First Half of 2020

Between January and July 2020, The American Journal of Managed Care®’s (AJMC®) most-read stories ranged from breaking COVID-19 news to revisions of blood donation guidance.

ART May Lower Risk of COVID-19 in Persons With HIV

June 29th 2020

ART May Lower Risk of COVID-19 in Persons With HIV

Being on an antiretroviral treatment (ART) regimen of tenofovir disoproxil fumarate/emtricitabine may lower the risk of HIV-positive individuals contracting coronavirus disease 2019 (COVID-19).

PAPER OF THE WEEK: In 1998, Research Highlighted Importance of Comorbidities in HIV Care

June 28th 2020

PAPER OF THE WEEK: In 1998, Research Highlighted Importance of Comorbidities in HIV Care

These findings highlighted that adherence to drugs is not the sole issue to address in patients with comorbidities also serving as vital factors in designing managed care plans.

This Week in Managed Care: June 26, 2020

June 26th 2020

This Week in Managed Care: June 26, 2020

This week, the top managed care news included CMS proposing rules for value-based contracting in Medicaid; claims data highlighting racial disparities in COVID-19 effects; an interview with Anthony Fauci, MD, on the progress made against HIV.

Opioid Use Has a Detrimental Effect on Uptake of Care for Uncontrolled HIV

June 24th 2020

Opioid Use Has a Detrimental Effect on Uptake of Care for Uncontrolled HIV

Individuals who self-report a problem with drugs, especially opioids, are more likely to have uncontrolled HIV, to not be adherent to antiretroviral therapy, and to engage less in primary care for their infection but more in risky behaviors, including sharing needles and having multiple concurrent sexual partners.

Fauci: Countless Lives Have Been Saved, but an HIV Vaccine and Cure Remain Elusive

June 21st 2020

Fauci: Countless Lives Have Been Saved, but an HIV Vaccine and Cure Remain Elusive

To mark the 25th anniversary of The American Journal of Managed Care®, we spoke with Anthony Fauci, MD, director of the National Institute of Allergy and Infectious Diseases (NIAID). Fauci has been at NIAID for 36 years, and he gave a keynote address at the 6th International AIDS Conference in San Francisco in 1990. Here he speaks on progress that has been made in the fight against HIV and AIDS, from AZT to Truvada to undetectable viral loads; why there is no cure just yet; and how the first tumultuous years of the AIDS crisis shaped research for decades to come.

June 19th 2020

From the Editor-in-Chief: Bigger Questions of Systems, Viruses, and the Lives of Real People

Joseph Alvarnas, MD

As I recall the early days of the HIV/AIDS pandemic, what stands out most is its profound human cost and the courage of those who helped our society transcend it. We are in the midst of a time in which the human toll of COVID-19 and the enormity of the path ahead are clear.

June 19th 2020

References for Humility and Hope, Alvarnas

Joseph Alvarnas, MD

References: Humility and Hope: Evolution of the HIV Pandemic, From ART to Today’s Cancer Cures

June 19th 2020

Humility and Hope: Evolution of the HIV Pandemic, From ART to Today's Cancer Cures

Joseph Alvarnas, MD

The connections between cancer and HIV/AIDS became clear relatively early in the HIV/AIDS pandemic and continue to this day. Not only were opportunistic infections present in a majority of HIV-infected patients who met the initial diagnostic criteria for AIDS, but several cancer types were far more prevalent as well. While there is still much to understand before HIV is fully conquered, we have already learned a great deal about the pathobiology of this virus that has helped advanced immune-oncological technologies and led to the development of increasingly effective gene therapy delivery systems.

June 18th 2020

Challenges and Similarities in HIV, COVID-19 Crises: A Q&A With Anthony Fauci, MD

Allison Inserro

To mark the 25th anniversary of The American Journal of Managed Care®, each issue in 2020 will include a special feature: an interview with a thought leader in the world of health care and medicine. The July issue features a conversation with Anthony Fauci, MD, director of the National Institute of Allergy and Infectious Diseases.

Having a High Risk of HCV Does Not Always Lead to Testing Among Those With HIV

June 18th 2020

Having a High Risk of HCV Does Not Always Lead to Testing Among Those With HIV

Despite the CDC’s recommendation, which has been in effect since 1998, study results show that just half of HIV-positive individuals choose to get tested for hepatitis C virus (HCV) in the 12 months following the receipt of their diagnosis.

June 17th 2020

Zaia Draws on Decades of Innovation in Infectious Disease for Breakthroughs in Gene Therapy

Known as a gene therapy pioneer, Zaia has spent almost 40 years at City of Hope, in Duarte, California. He was first drawn by the promise of studying cytomegalovirus. Over the decades, his groundbreaking research has encompassed HIV/AIDS, cellular gene transfer therapy, immunotherapy, bispecific antibodies, and now hyperimmune globulin for workers on the frontlines of the coronavirus disease 2019 (COVID-19) pandemic.

Survival Disadvantages Persist Among Persons With HIV

June 15th 2020

Survival Disadvantages Persist Among Persons With HIV

Despite initiating antiretroviral therapy, overall and comorbidity-free–associated survival remain below that of the population without HIV.

Having COVID-19 May Not Increase Risk for Worse Outcomes Among Patients With HIV

June 12th 2020

Having COVID-19 May Not Increase Risk for Worse Outcomes Among Patients With HIV

Study results show a 4% mortality rate among HIV-positive patients who have coronavirus disease 2019 (COVID-19) compared with approximately 17% of patients who also have COVID-19 but are HIV-negative.

Prior Authorization for PrEP More Prominent in the South, May Represent Barrier to Care

June 10th 2020

Prior Authorization for PrEP More Prominent in the South, May Represent Barrier to Care

When used correctly, pre-exposure prophylaxis (PrEP) is effective more than 90% of the time, saving upward of $400,000 per averted HIV transmission.

Is There an Optimal Age at Which to Disclose HIV-Positive Status to Youth? Study Says Yes

June 5th 2020

Is There an Optimal Age at Which to Disclose HIV-Positive Status to Youth? Study Says Yes

Of the 1.8 million youth living with HIV around the world, the United States is home to 2000, and many were infected perinatally.

Possible Link Found Between Recent HIV Results, Testing-Related Behavior

June 3rd 2020

Possible Link Found Between Recent HIV Results, Testing-Related Behavior

There was a 6% increase from 2005 to 2014 in new HIV diagnoses among gay, bisexual, and other men who have sex with men, according to the CDC and study results published in Journal of Epidemiology and Community Health, and 1 in 6 is estimated to test positive for the disease at some point in his lifetime.

Does Gut Microbiota Influence Outcomes Among People With HIV?

May 29th 2020

Does Gut Microbiota Influence Outcomes Among People With HIV?

The life expectancy of a person living with HIV is approaching that of the general, seronegative population. However, changes to the bacterial environment of the intestinal tract combined with age-associated noncommunicable diseases can lead to chronic inflammation and higher rates of death.

Persons Living With HIV Have a Higher Risk of Recurrent Blood Clots

May 28th 2020

Persons Living With HIV Have a Higher Risk of Recurrent Blood Clots

Close to 40 million individuals are infected with HIV globally. A new study describes how some have a higher risk for a first venous thromboembolism that is 2 to 10 times above that of the general population.

How Does the Risk of HIV-1 Increase With Female Genital Schistosomiasis Infection?

May 22nd 2020

How Does the Risk of HIV-1 Increase With Female Genital Schistosomiasis Infection?

Schistosomiasis is the world’s second deadliest parasitic disease, and it can be linked to contaminated freshwater, with a majority of infections resulting from 3 types of bacteria: Schistosoma mansoni, S haematobium, or S japonicum. It is also a proposed factor for increasing the risk of HIV-1 infection in women.

Older Adults on ART Have Double the Mortality Risk of Their HIV-Negative Counterparts

May 21st 2020

Older Adults on ART Have Double the Mortality Risk of Their HIV-Negative Counterparts

Persons 50 years and older accounted for 3.6 million individuals living with HIV in 2013, and this number almost doubled to an estimated 6.7 million by 2017. Not all, however, are on antiretroviral therapy (ART).

Flexibility Is Key to Providing Ongoing Services to an HIV-Positive Population During the COVID-19 Pandemic

May 15th 2020

Flexibility Is Key to Providing Ongoing Services to an HIV-Positive Population During the COVID-19 Pandemic

Washington is home to 2 pertinent developments in the arrival of coronavirus disease 2019 (COVID-19) to the United States: the first US case of the virus was reported in the state on January 21 and the first major US city to report deaths as a result was Seattle.

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