Provider Barriers in Uptake of Biosimilars: Case Study on Filgrastim
Previous studies have found modest uptake of biosimilars in both commercial and Medicare populations. This study finds that the uptake varies between the rural and urban provider settings.
Changes in Opioid Marketing Practices After Release of the CDC Guidelines
After the CDC guidelines’ release, total opioid marketing spending and encounters per physician decreased, but spending per encounter subsequently increased.
Site of Care Potentially Limits Cost Savings From Biosimilars
Although previous work has found lower costs for biosimilar filgrastim compared with reference filgrastim, this study found that site of care can change this calculus, reducing savings.
The Potential Impact of CAR T-Cell Treatment Delays on Society
Treatment delays limit the social value generated by chimeric antigen receptor (CAR) T-cell therapy for the treatment of pediatric acute lymphoblastic leukemia and diffuse large B-cell lymphoma.
Association Between FDA Black Box Warnings and Medicare Formulary Coverage Changes
Medicare formularies were inconsistent in increasing restrictiveness to drugs that received FDA black box warnings for death and/or cardiovascular risk with safer available drug alternatives.
Impact of New Drugs and Biologics on Colorectal Cancer Treatment and Costs
We measured the financial consequences of new CRC treatment regimens. New regimens have increased cost directly through price and indirectly through nonstandard and second-line regimen use.