Association Between FDA Black Box Warnings and Medicare Formulary Coverage Changes
Medicare formularies were inconsistent in increasing restrictiveness to drugs that received FDA black box warnings for death and/or cardiovascular risk with safer available drug alternatives.
An enhanced risk model incorporating medication use, prior healthcare utilization, and mental health with comorbid health conditions predicts healthcare utilization better than health conditions alone.
Adoption of New Agents and Changes in Treatment Patterns for Hepatitis C: 2010-2014
New hepatitis C medications have been quickly adopted into practice and increased treatment rate. The median out-of-pocket costs of new medications were relatively low.
Changing Trends in Type 2 Diabetes Mellitus Treatment Intensification, 2002-2010
Glycemic control can lower the risk of diabetes-related complications, and delayed treatment intensification can impede optimal diabetes care.This study examines trends in hyperglycemia treatment intensification between 2002 and 2010.
Simple Errors in Interpretation and Publication Can Be Costly
A recent AJMC study contained overstatements and small but importantly placed errors that have the potential to cause unwarranted on-the-ground cost problems.
Risk-Stratification Methods for Identifying Patients for Care Coordination
Identifying which patients are likely to benefit from care coordination is important. We evaluated the performance of 6 risk-screening instruments in predicting healthcare utilization.
Asthma Expenditures in the United States Comparing 2004 to 2006 and 1996 to 1998
Increased expenditures in US asthma are driven by increased medication spending that are not offset by decreases in emergency department and hospital spending.
Impact of New Drugs and Biologics on Colorectal Cancer Treatment and Costs
We measured the financial consequences of new CRC treatment regimens. New regimens have increased cost directly through price and indirectly through nonstandard and second-line regimen use.
Effect of Multiple Chronic Conditions Among Working-Age Adults
Multiple chronic conditions among working-age adults lead to high costs over many years. Understanding how to effectively manage such patients is an important challenge.