Jared Kaltwasser

Among the 10 patients in the retrospective analysis, the median overall survival after allogeneic hematopoietic stem cell transplantation (allo-HSCT) for relapsed/refractory diffuse large B-cell lymphoma (R/R DLBCL) was 21 months.

The study may help explain why some patients are more prone to relapse following a complete response to induction therapy, as indicated by measurable residual disease (MRD) status and 2017 European LeukemiaNet (ELN) criteria.

The authors suggest the phenomenon of 2 mutationally distinct diffuse large B-cell lymphomas (DLBCLs) might be more common than currently understood.

Investigators say attempts to overcome mutational resistance to Bruton’s tyrosine kinase (BTK) inhibitors have had mixed results among patients who have chronic lymphocytic leukemia (CLL).

New methods of classifying patients could pave the way for more personalized treatment approaches, a new report states.

A new report compared the blood immune repertoires of patients with chronic lymphocytic leukemia (CLL) who received chemoimmunotherapy and those who received ibrutinib.

Although ibrutinib adds to the cost of treatment, its benefits over the long term justify the cost, investigators found.

Investigators said analysis of multiple tissues from the same patients suggests tumor evolution in high-grade serous ovarian cancer (HGSC) was not through somatic mutations.

Investigators say computer algorithms can be used to assess physical and vocal signs of myasthenia gravis (MG).

Full team coverage from the European Hematology Association 2023 Hybrid Congress, which took place June 8-11 in Frankfurt, Germany.

The study also found people with vitamin D deficiency had a lower mortality rate from Clostridioides difficile infection (CDI).

The study was designed to help scientists better understand how to prevent in-hospital transmission of Clostridioides difficile.

Committees have worked for the past 4 years to develop uniform definitions of immunotherapy resistance, but they are not yet universally used.

Investigators said the fact that their patient was 82 years old was one reason to suspect fluid overload–associated large B-cell lymphoma (LBCL).

The greatest reduction in skeletal muscle mass was in the lower extremities, a new report shows.

By giving their patient the correct diagnosis, clinicians avoided costlier treatments for thrombotic thrombocytopenic purpura (TTP) like plasmapheresis.

Investigators say their research could open new avenues of investigation into Chagas disease, the often-neglected tropical disease.

Barriers to acceptance included privacy concerns and fears about the possibility of misinterpretation of messages.

Congenital thrombotic thrombocytopenic purpura (TTP), an ultra-rare disease, can significantly impact quality of life, but clinicians have previously lacked a disease-specific way to track experiences via patient-reported outcomes (PROs).

Fewer patients opt to skip therapy for their multiple myeloma (MM) despite progressive disease than previously thought, a new study suggests.

Highly resourced accountable care organizations (ACOs) were more likely to offer digital health services.

Better diagnostic tests and wider availability of low-cost vaccines would help further decrease cases, the authors said

People with psoriasis were also more likely to have pulmonary comorbidities compared with those who did not have psoriasis.

Investigators looked at both primary and metastatic tumors and found correlations between characteristics and patient outcomes.

The most common treatments come with significant cardiovascular risk, but study investigators suggest newer options might offer a more favorable risk profile.

Study authors say the consequences of misdiagnosing osteomyelitis can be severe in the disease setting of sickle cell disease (SCD).

Significant mechanobiological advances have not yet been incorporated into oncology treatment, the authors wrote. 

Authors describe 3 patients with cancer who were given interleukin-23 (IL-23) inhibitors for psoriasis or immune-related psoriasis.

Most cases of high-grade serous ovarian cancer are not diagnosed until the disease has reached an advanced stage.

Surgery can be difficult in such cases of diffuse large B-cell lymphoma (DLBCL), but it leads to significant better outcomes, study authors said.