AJMC Staff

An abnormal retention of mitochondria can trigger the cascade of inappropriate and harmful immune activity that is characteristic of lupus, the report said.

The issue of systemic lupus erythematosus (SLE) is particularly important in Asia, because patients there suffer from more severe disease and damage compared with patients in Western countries.

Molecular profiling is more often used after standard cancer treatments have failed; a recent study suggests that it could effectively guide first-line treatment, especially for cancers with a poor prognosis.

A recent study found that nurses who worked in operating rooms for 15 or more years are 46% to 69% more likely to develop chronic obstructive pulmonary disease (COPD) than nurses who had never worked in an operating room.

Angelman syndrome affects roughly 1 in every 20,000 children and it has no approved treatment.

Researchers hope that the benefits seen in a new protocol for deep brain stimulation (DBS) in Parkinsonian mice will extend to humans.

A study funded by the National Institutes of Health found that Glucosyltransferase domain is a possible molecular target for therapeutic interventions for Clostridioides difficile infection.

A report suggests that people with chronic obstructive pulmonary disease (COPD) and asthma have a protein in their lungs that leaks a small molecule into their bloodstream that restricts their breathing instead of relaxing their airways.

Health care costs are 3 to 5 times greater for people with rare diseases compared with those without, according to a new study.

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Recipients of Pfizer’s COVID-19 booster shot had a 95.6% lower risk of infection than fully vaccinated individuals who received placebo; analysis finds Biden’s social spending and climate change bill would significantly reduce rates of uninsurance; Texas urges Supreme Court to let its abortion law stand.

A recent review sought to analyze studies to identify a neuropsychological assessment to evaluate cognitive domains and neuropsychological changes.

The FDA approves Moderna and Johnson & Johnson COVID-19 booster shots and will allow mixing-and-matching for boosters; the health-related effects of climate change are growing; there is a rise in poisonings tied to the antiparasitic drug ivermectin.

Sold under the name Dupixent, dupilumab is a biologic that inhibits interleukin (IL)-4 and IL-13, which are key drivers of the type 2 inflammation that plays a major role in asthma, chronic rhinosinusitis with nasal polyps, atopic dermatitis, and eosinophilic esophagitis.

Surgeons attached the kidney of a genetically altered pig to the outside of a human body; an FDA proposal may help up to 37.5 million Americans with hearing loss; Women pregnant with girls have higher levels of COVID-19 antibodies.

The Biden administration moves to regulate certain toxic chemicals; the FDA is expected to endorse mixing and matching vaccine boosters; nurse shortages could lead to care rationing in New Mexico.

Merck has submitted data on its COVID-19 pill to the FDA after a successful trial; air, land, and ferry travelers will be allowed into the United States in November if they show proof of vaccination; 13 of 33 certified community behavioral health clinics in Michigan will be reimbursed by Medicaid.

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An independent FDA advisory panel endorses Moderna boosters for select groups; circuit court lets Texas abortion law stand, paving the way for appeals; Robert Califf, MD, is reportedly being eyed to head the FDA again.

A federal judge denied a bid to stall the implementation of Purdue Pharma’s bankruptcy plan; Social Security checks are expected to increase in 2022; the FDA has released guidelines for the food industry aimed at lowering sodium levels.

The FDA authorizes the first e-cigarette; an FDA meeting will discuss mix-and-match booster vaccines; OSHA submitted the initial text of an emergency vaccine rule to the OMB for review.

DOJ requests federal appeals court to block grant of stay for Texas' abortion law; common synthetic chemicals linked with premature death; influenza hospitalization and death more likely in pediatric minority populations.

The product, called Rethymic, is composed of human allogeneic thymus tissue that is processed and cultured and then implanted into children born without a thymus to help reconstitute immunity.

Environmental Protection Agency (EPA) to announce plan on strengthening regulations against certain chemicals; risk of emergency complications increased in pregnant women with symptomatic COVID-19; fully vaccinated, heavy marijuana users with substance abuse disorder linked with higher susceptibility to breakthrough infection.

Comparing liver cancer survival across high-income countries has been difficult due to different standard and coding practices

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New data show a decrease in COVID-19 deaths in the United States; long-term exposure to low levels of air pollution increases mortality risk; Moderna pressured to ramp up vaccine production.

Pfizer and BioNTech ask FDA to authorize their COVID-19 vaccine in children; the World Health Organization (WHO) recommended widespread use of the world’s first malaria vaccine; a US judge blocks Texas’ strict abortion law.

Anxiety and depression rates increased 13% and 14.8%, respectively, in 2020, before declining in 2021; Anthem Blue Cross and UnitedHealthcare are among major insurers behind on payments; a federal investigation discovered racial and gender-based pay discrimination among sales representatives at AstraZeneca.

Francis Collins, MD, PhD, will step down as director of the National Institutes of Health (NIH) at the end of the year; the Biden administration ends a ban on federal funds for clinics that provide abortion referrals; the Pfizer/BioNTech COVID-19 vaccine is 90% effective in preventing hospitalization and death 6 months after the second dose.