Johnson & Johnson (J&J) ends late-stage HIV vaccine trial; mothers in states with abortion bans are almost 3 times more likely to die before, during, and after birth; Sanofi hopes to release a drug for hemophilia A in 2023.
J&J Will Stop HIV Vaccine Trial
Following evidence of ineffectiveness against infection prevention, Johnson & Johnson (J&J) will discontinue a late-stage worldwide trial of an HIV vaccine, Reuters reported. The news comes over a year after another unsuccessful vaccine study by J&J. A spokesperson who was a partner in the trial said that they will take the information from this trial put it to use in the future. The study started in 2019 at more than 50 locations, comprising about 3900 gay men and transgender people, who are deemed most susceptible to the infection.
States Banning Abortion More Likely to Have Maternal Deaths
Death in women during pregnancy, childbirth, or postpartum is almost 3 times more likely in states with abortion bans, Axios said, after reviewing a report from the Gender Equity Policy Institute. Almost 60% of US women live in states that ban or restrict abortion and other reproductive health care. In 2021, the maternal mortality rate in states with abortion bans was 2.4 times higher than that of states supporting abortion, according to the report, with women of color being the most affected.
Sanofi Strives to Introduce Hemophilia A Drug in 2023
French drug manufacturer Sanofi SA has high hopes for efanesoctocog alfa, its hemophilia A drug, in 2023, according to Reuters. The drug is being created in conjunction with Swedish drug producer Sobi; a decision by the FDA is expected by February 28. The marketing application was accepted by the FDA in 2022. An estimated 400 babies per year are born with the disorder, and possibly more.
Review: One-Shot Etranacogene Dezaparvovec Represents Game-Changing Gene Therapy for Hemophilia B
May 3rd 2024More than 20 years of gene therapy clinical research have led to etranacogene dezaparvovec’s use in hemophilia B, according to authors of a recent review—and it takes its place in a line of current and potentially many future genomic medicines for a range of diseases.
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Examining Low-Value Cancer Care Trends Amidst the COVID-19 Pandemic
April 25th 2024On this episode of Managed Care Cast, we're talking with the authors of a study published in the April 2024 issue of The American Journal of Managed Care® about their findings on the rates of low-value cancer care services throughout the COVID-19 pandemic.
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A new federal rule will enable thousands of immigrants in the Deferred Action for Childhood Arrivals (DACA) program to obtain health care through the Affordable Care Act; a forthcoming CMS rule is expected to lower home-based care wait times and raise caregiver wages; the HHS Office for Civil Rights has finalized 2 rules that strengthen the ACA’s health care discrimination ban.
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Navigating Health Literacy, Social Determinants, and Discrimination in National Health Plans
February 13th 2024On this episode of Managed Care Cast, we're talking with the authors of a study published in the February 2024 issue of The American Journal of Managed Care® about their findings on how health plans can screen for health literacy, social determinants of health, and perceived health care discrimination.
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Initiating BP Medication Linked to Higher Fall, Fracture Risks in Nursing Home Residents
May 2nd 2024Among over 60,000 nursing home residents who initiated antihypertensive medication, rates of excess fractures due to falls per 100 person-years were as high as 5 among certain patient groups, such as those with dementia and high blood pressure (BP).
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