The Future of Ph+ ALL Treatments

EP: 1.Overview of Characteristics Unique to Ph+ ALL

EP: 2.Timely Detection: Incidence and Prevalence of Ph+ ALL

EP: 3.Supporting Ph+ ALL Patient: Emotional Challenges and Quality of Life

EP: 4.Screening and Diagnosing of Ph+ ALL in Adults

EP: 5.Diagnosis and Treatment Timeline: Different Phases of Ph+ ALL Management

EP: 6.Current Front-Line Targeted Treatments in Ph+ ALL

EP: 7.Prior Authorization and Access to Targeted Treatment for Ph+ ALL Patients

EP: 8.PhALLCON Trial: Efficacy and Safety of Ponatinib in Ph+ ALL Patients

EP: 9.Value-Based Care Models Optimizing Ph+ ALL Patient Care

EP: 10.Unmet Needs in Screening, Diagnosis, and Management of Ph+ ALL

EP: 11.Disparities in Access to Care for Ph+ ALL patients

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EP: 12.The Future of Ph+ ALL Treatments

EP: 13.Concluding Thoughts on Ph+ ALL Treatment

This is a video synopsis/summary of a Peer Exchange involving: Ryan Haumschild, PharmD, MS, MBA; Jonathan Abbas, MD; Elias Jabbour, MD; James K. McCloskey, MD; Vivian Tambe Ebot-Tar, PharmD, MBA.

The discussants envisioned the future Philadelphia chromosome–positive acute lymphoblastic leukemia (Ph+ ALL) landscape. Dr Jabbour foresees identifying patients still needing intensive therapy, better tyrosine kinase inhibitors, preventing central nervous system relapse, and potentially stopping therapy after several years via measurable residual disease monitoring. Chemo-free approaches are imminent. Dr McCloskey concurred, highlighting community implementation challenges but tremendous improvements for quality of life. Dr Abbas contrasted historic posttransplant outcomes with far superior responses from today’s oral targeted therapy. Further optimizing initial Ph+ ALL treatment stands to enrich more patient lives. Ongoing advances promise even brighter futures.

Video synopsis is AI-generated and reviewed by AJMC® editorial staff.