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Opinion|Videos|December 4, 2024
LEMS and SCLC: Unraveling the Neuromuscular-Cancer Connection
Author(s)Wade Iams, MD
Key Takeaways
- LEMS is an autoimmune disorder linked to SCLC, causing muscle weakness and autonomic dysfunction due to presynaptic calcium channel antibodies.
- Differentiation from myasthenia gravis involves recognizing presynaptic involvement and specific antibody profiles in LEMS.
A medical expert discusses how Lambert-Eaton myasthenic syndrome is closely linked to small cell lung cancer, the challenges in differentiating it from other neuromuscular disorders like myasthenia gravis, and the impact of dual diagnosis on cancer care and patient outcomes.
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Episodes in this series
Video content above is prompted by the following:
- What is Lambert-Eaton myasthenic syndrome (LEMS), and what is the connection between LEMS and small cell lung cancer (SCLC)?
- How does LEMS in patients with SCLC differ from other neuromuscular disorders that may be on the differential, such as myasthenia gravis?
- What are the long-term effects of LEMS on physical and mental health, and how do they vary across different patient populations?
- How does the dual diagnosis of SCLC and LEMS affect the trajectory of cancer care for patients?
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