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Exploring the Pathophysiology and Diagnosis of Bronchiectasis

A panelist discusses how bronchiectasis involves a vicious cycle of airway damage, where neutrophilic inflammation leads to bronchial wall destruction and dilation, while explaining that diagnosis relies primarily on high-resolution CT imaging showing bronchial wall thickening and dilated airways, distinguishing it from the emphysematous changes seen with chronic obstructive pulmonary disease (COPD).

Video content above is prompted by the following:

  • Can you please describe the pathophysiology of bronchiectasis, specifically the role of neutrophilic inflammation?
  • How is bronchiectasis diagnosed in clinical practice, and how is it differentiated from other pulmonary diseases like COPD?
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