The AJMC® clinical page includes all the published content across AJMC.com, The American Journal of Managed Care® and Evidence-Based Oncology™ on a variety of specialties, including dermatology, cardiology, oncology, and rheumatology.
November 8th 2024
The chimeric antigen receptor T-cell therapy obecabtagene autoleucel received approval to treat patients with relapsed or refractory (R/R) B-cell acute lymphoblastic leukemia.
Study Underscores Role of Mutations in TERT Promoter in Cancer
May 19th 2015A Science study found that recurrent mutations in the promoter of the telomerase gene, TERT, could be responsible for overexpression of telomerase in a majority of cancers, thereby sustaining the replicative potential of cancer cells.
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Toujeo and Afrezza: New and Improved Insulins, Limited by FDA Labeling Constraints
May 19th 2015Two new insulins marketed by Sanofi offer improved options for patients: Toujeo is longer acting than its predecessor, Lantus. Afrezza, an inhaled insulin, is gaining praise from patients, if not from Wall Street.
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Physician Misdiagnosis Leads to Inappropriate Antibiotic Use, Study Finds
May 19th 2015Findings of a study published in Infection Control & Hospital Epidemiology show that 95% of inpatients at a VA hospital in Minneapolis with an incorrect or indeterminate diagnosis, were given inappropriate antibiotics, as opposed to 38% who were accurately diagnosed, yet administered incorrect medication.
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Drop-off in Prostate Screening Stirs Controversy at AUA Meeting
May 19th 2015Data presented at the American Urological Association in New Orleans show a 50% drop in PSA testing in the years since the USPSTF issued its controversial D recommendation. Some see a "chilling" effect, but not all see a problem.
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Urologist Evaluates Implications of the Removal of Flawed SEER PSA Data
May 19th 2015Large data sets like SEER need better quality control checks and researchers and clinicians who use these data sets should also consider using secondary data analyses that answer specific research questions. This is the advice of a senior urologist following the removal of the PSA data.
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Study Associates Experience With Outcomes in Robotic Prostate Cancer Surgery
May 18th 2015The study, conducted by researchers at the Henry Ford Hospital, found that complications associated with robot-assisted radical prostatectomies were higher in low-volume hospitals, with relatively inexperienced staff.
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Expert Calls for Improved Home Care Options for Those With Debilitating Diseases
May 18th 2015Karen Davis, director of Roger C. Lipitz Center for Integrated Health Care at Johns Hopkins University, says increasing resources available for home treatments and services and support for family caregivers of the elderly and those with debilitating diseases might work to reduce reliance on costly nursing homes for those afflicted.
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FDA Warns That SGLT2 Inhibitors May Result in Ketoacidosis
May 18th 2015The FDA said it had received 20 reports in the 15 months since the first of the SGLT2 inhibitor class was approved, and had continued to receive reports since that time. All drugs in the class were included in the safety communication.
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Costs of Venous Thromboembolism Associated With Hospitalization for Medical Illness
Venous thromboembolism during or after recent hospitalization for medical illness contributes a substantial economic burden to society across all hospital and ambulatory care delivered.
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New Reference Standards Could Ensure Standardization of Genetic Test Results
May 15th 2015The National Institute of Standards and Technology has released new reference standards that could help diagnostic laboratories standardize their equipment and software to reduce variability in genetic test results between laboratories.
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Campaign Improved Screening Rates for Throat Cancer in Florida
May 15th 2015Raising awareness of the dangers of mouth and throat cancer increased the number of black men in some of Florida's poorest counties who sought screening for the first time, which could improve survival rates through early detection and treatment.
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FDA Provides New Guidance to Manufacturers on Biosimilars
May 14th 2015While the marketing of the first biosimilar to be approved in the US market, Zarxio, has been delayed due to a court order, the FDA is providing guidance to manufacturers to help them effectively navigate the process of product development.
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