The AJMC® clinical page includes all the published content across AJMC.com, The American Journal of Managed Care® and Evidence-Based Oncology™ on a variety of specialties, including dermatology, cardiology, oncology, and rheumatology.
April 18th 2025
From Crohn disease to uncomplicated urinary tract infections and beyond, the FDA issued several high-impact drug approvals last month.
Review Discusses Pneumonitis as an Adverse Effect of Checkpoint Inhibitors
July 10th 2017Research published by Cancer Management & Research explores the efficacy of treating multiple malignancies with immune checkpoint inhibitors and programmed cell death-1 inhibitors (PD-1). The review specifically analyzes the presence of pneumonitis as an adverse event following treatment of checkpoint inhibitors.
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Prescription Fills for High-Intensity Statins Increased from 2011 to 2014
July 6th 2017From 2011 to 2014 the use of high-intensity statins following hospitalization for myocardial infarction (MI) increased progressively, according to a study published in Journal of the American College of Cardiology.
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Dr Alan Carter on Increasing Insulin Costs
July 4th 2017Material suppliers, manufacturers, pharmacies, and rebate programs all contribute to the rising prices of insulin, according to Alan Carter, PharmD, principal investigator and senior advisor at MRIGlobal, and adjunct faculty at University of Missouri—Kansas City School of Pharmacy.
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Immuno-Oncology Drug, AM0010, Is Effective in Treating Advanced Pancreatic Cancer
July 4th 2017New clinical trial research presented at the European Society for Medical Oncology 19th World Congress on Gastrointestinal Cancer suggests that ARMO BioSciences’ immuno-oncology drug, AM0010, is effective in treating patients with advanced pancreatic cancer.
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COPD Exacerbations May Lead to Increased Risk of Heart Attack and Stroke in CVD Patients
July 4th 2017Those with chronic obstructive pulmonary disease (COPD) may be more likely to suffer from a heart attack or stroke following an acute exacerbation if they have a history or at risk of cardiovascular disease (CVD).
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New Flow Cytometry-Based Test Approved for Certain Leukemias and Lymphomas
July 3rd 2017A new liquid biopsy test that uses flow cytometry to detect cancer cells has been FDA approved for chronic leukemia, acute leukemia, non-Hodgkin lymphoma, myeloma, myelodysplastic syndrome, and myeloproliferative neoplasms.
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Dr William Polonsky on Diabetes Patients' Treatment Satisfaction and Insulin Adherence
June 29th 2017Diabetes patients will be more satisfied with treatment when they perceive benefits and will continue treatment when physicians keep in contact and point out the progress, says William Polonsky, PhD, CDE, president of the Behavioral Diabetes Institute and associate clinical professor at University of California, San Diego.
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Nivolumab Improved Patient-Reported QOL Compared With Investigator's Choice: CheckMate 141
June 28th 2017The study, published in Lancet Oncology, has found that nivolumab reduced the rate of clinically meaningful deterioration compared with investigator’s choice among platinum-refractory patients being treated for recurrent or metastatic head and neck cancer.
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Infusing a Sense of Urgency in Cancer Care: The Biden Cancer Initiative
June 27th 2017On Monday, June 26, 2017, the Biden Foundation announced the launch of the Biden Cancer Initiative, their new venture to continue the fight to make progress in cancer prevention, detection, treatment, and care.
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Study Investigates Treatment Trends in COPD and Asthma–COPD Overlap Patients
June 27th 2017While treatments prescribed for people with chronic pulmonary disease (COPD) and asthma—COPD overlap syndrome (ACOS) are similar, there is a need for a clearer therapeutic approach for patients with ACOS, according to a new study.
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Understanding Stakeholder Objectives, and Aligning Them, in Cancer Care
June 26th 2017At the 8th Annual Oncology Market Access & Pricing USA 2017 meeting hosted by eyeforpharma, the discussion included raw material short supplies, pragmatic trials, risk-sharing, and understanding these challenges to meet stakeholder goals.
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Diagnostic Immunoassays Could Spare Patients High-Risk Pancreatic Resection
June 25th 2017Researchers at Indiana University have confirmed the clinical utility of 2 laboratory tests that can distinguish benign pancreatic cancer lesions that mimic early signs of cancer and spare patients of unnecessary pancreatic cancer screenings or surgeries.
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FDA Approves Rituxan Hycela for Treating Certain Blood Cancers
June 24th 2017The FDA has approved Genentech’s Rituxan Hycela for subcutaneous injection for the treatment of certain blood cancers. Rituxan Hycela has similar outcomes as Rituxan, but can be delivered in 5 to 7 minutes compared with 1.5 hours for Rituxan.
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Genentech's Ocrevus Reduces Disease Progression in Multiple Sclerosis Patients
June 23rd 2017A phase 3 clinical trial of patients with relapsing multiple sclerosis and primary progressive multiple sclerosis found that Ocrevus (ocrelizumab) significantly reduced disease progression, according to results released by Genentech.
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FDA Approves of Darzalex Combination for Multiple Myeloma
June 23rd 2017The FDA has approved the use of Janssen Biotech, Inc’s immunotherapy Darzalex in combination with pomalidomide and dexamethasone. Darzalex is used to treat multiple myeloma patients who have previously received at least 2 therapies with lenalidomide and a proteasome inhibitor.
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FDA Approves Baxdela for Skin Infections
June 22nd 2017The FDA has approved Baxdela, a drug intended to treat adults with acute bacterial skin and skin structure infections caused by susceptible bacteria. Baxdela is also effective in treating MRSA and against other gram-positive or gram-negative pathogens.
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Analysis of COPD Hospitalization Trends Finds Gender Gap for Mortality
June 20th 2017With more women dying annually from chronic obstructive pulmonary disease (COPD) than men since 2000, researchers have examined trends in COPD hospitalization and in-hospital mortality, evaluating for differences by sex and race. They presented their research at the American Thoracic Society 2017 International Conference.
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Diagnostic Test Brings a Precision Medicine Approach to Prostate Cancer Drug
June 19th 2017A collaborative study among scientists working across 3 continents has found a strong association between circulating free DNA in patients being treated with olaparib (Lynparza) for prostate cancer and disease outcome.
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