Clinical

Specialists address the intricate factors between comorbidities, efficacy, and tolerance, which influence their treatment approaches at the time of diagnosis.

Specialists evaluate their clinical strategies for managing second-line driver-negative and initial PD-L1 negative patients.

The researchers noted that their findings suggest clinicians and policy makers should encourage hepatitis C virus (HCV) treatment in those with unhealthy alcohol consumption or alcohol use disorder (AUD) rather than create barriers to it.

Medical experts discuss considerations for ESRD during CKD treatment as well as updated guidelines for treatment of chronic kidney disease.

Jennifer Green, MD, provides considerations for the use of SGLT2 inhibitors in treatment of CKD.

Following discussions with FDA, Takeda will voluntarily withdraw mobocertinib in the United States for adult patients with EGFR exon 20 insertion mutation–positive, locally advanced or metastatic non–small cell lung cancer (NSCLC) based on the outcomes of the phase 3 EXCLAIM-2 trial.

Major companies committed to joining Medicare drug price negotiations; Boehringer Ingelheim introduced a low-cost version of its adalimumab biosimilar; schools begin to stock naloxone amid rising opioid deaths among young people.

The chosen studies featured various methods to assess medication use initiation, implementation, and/or persistence in patients with chronic obstructive pulmonary disease (COPD).

Severe cases of COVID-19 and COVID-19–related deaths were associated with sickle cell disease.

Nedosiran (Rivfloza) was approved for children and adults with primary hyperoxaluria type 1 (PH1), according to drugmaker Novo Nordisk.

Atrioventricular interval modulation (AVIM) therapy for hypertension may help address this common comorbidity among patients with pacemakers.

An overview on the current role of caregivers on patient adherence.

An explanation on the importance of cooperation on the side of providers, payers, and pharmacists in treatment of patients.

A new grant aims to address maternal mortality in predominantly Black rural areas; Eli Lilly's drug to treat atopic dermatitis has not received FDA approval; a preliminary injunction is granted to Planned Parenthood South Atlantic.

Katalin Karikó, PhD, and Drew Weissman, MD, PhD, were cited "for their discoveries concerning nucleoside base modifications that enabled the development of effective mRNA vaccines against COVID-19."

These new findings may help shape both the design and the use of an educational intervention on technology-based inhaler techniques for patients with pediatric asthma.

The researchers found that social frailty was prevalent in 36.8% of patients with chronic obstructive pulmonary disease (COPD) in the study population.

Sarcopenia or myosteatosis combined with low prediagnostic physical exercise was associated with increased mortality from colorectal cancer (CRC).

FDA action is no longer expected in Q3 of 2023.

Recent evidence suggests that neoadjuvant immunotherapy offers a unique opportunity to explore disease mechanisms and identify new biomarkers of immune checkpoint blockade response and resistance, according to the researchers.

Medical experts discuss the financial impact of early detection in colorectal cancer.

Ryan Haumschild, PharmD, MS, MBA, drives a conversation regarding the epidemiology of metastatic colorectal cancer (mCRC) in the US.

Key recommendations and recent updates in the latest version of NCCN guidelines for DLBCL are outlined by Dr Gordon.

Leo Gordon, MD, provides an overview of current treatment strategies currently driven by NCCN guidelines.

Those with certain comorbidities, including peptic ulcer disease and renal failure, were at additional risk of developing Clostridioides difficile infection.