Latest Conference Content

In abstracts featured at the 2022 European Hematology Association Congress, investigators detailed long-term results of the ASPEN phase 3 trial and an expanded access study of zanubrutinib in patients with Waldenström macroglobulinemia (WM).

Mazyar Shadman, MD, MPH, of Fred Hutchinson Cancer Research Center and University of Washington, discussed positive health-related quality of life (HRQOL) findings of the SEQUOIA trial investigating zanubrutinib vs bendamustine/rituximab in the treatment of chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL).

An education session at the 2022 European Hematology Association Congress featured updates on using genetic and immune characteristics to select the optimal treatment pathway in chronic lymphocytic leukemia (CLL).

Many socioeconomic factors, such as neighborhood factors, access to care, and education can influence sleep, explained Cinthya Pena Orbea, MD, assistant professor of medicine, Cleveland Clinic.

Once-nightly sodium oxybate was associated with a statistically significant reduction in cataplexy episodes among patients with narcolepsy, explained Michael Thorpy, MD, director of the Sleep-Wake Disorders Center at Montefiore Medical Center and professor of neurology at Albert Einstein College of Medicine.

A panel of providers and patients with narcolepsy who are parents shared the struggles and possible support tools that neurologists and other providers should be aware of when caring for patients with narcolepsy who are pregnant or postpartum.

During her presentation at SLEEP 2022, Isabelle Arnulf, MD, PhD, a neurologist and professor, detailed the long list of challenges for understanding different aspects of idiopathic hypersomnia and called for more attention to be devoted to future research.

The 2022 European Hematology Association (EHA) Congress will be the group’s first hybrid meeting, in which investigators will convene both virtually and in Vienna, Austria, from June 9-12, 2022, to present cutting-edge findings in the realm of oncology and hematology.

While consumer wearables for sleep are popular, evidence-based guidelines need to be established to interpret data coming from these technologies, said Sean Drummond, PhD, professor of clinical neuroscience, Turner Institute for Brain and Mental Health at Monash University.

Presenters from SLEEP 2022 contextualized some of the recent research showing the impact of sleep disorders on aspects of mental health, including depressive symptoms and suicide.

Michael Johnson, CEO of Rhinomed, expands on the findings of the 2022 Annual Global Sleep and Snoring Report conducted in February 2022, which found that people are not getting nearly as much sleep as they should.

The results involve a pair of DNA medicines combined with cemiplimab, which is approved as Libtayo to treat other solid tumors. In this study, the regimen is designed to prime a T-cell response before a patient receives radiation.

Behavioral and physiological components of type 1 diabetes and its management can contribute to worsened sleep and health outcomes, which can vary by age, according to Stacey Simon, PhD, sleep psychologist and associate professor, University of Colorado Denver, Children's Hospital Colorado.

Susan Redline, MD, MPH, the SLEEP 2022 meeting keynote speaker, catalogued the evidence proving that continuous positive airway pressure (CPAP) does improve health outcomes—refuting a recent controversial report that claims otherwise.

Opioids have been used for hundreds of years to treat restless leg syndrome (RLS), but there is currently a registry to understand the long-term effectiveness of opioids to treat RLS , said John Winkelman, MD, PhD, medical director, sleep disorders clinical research program, Massachusetts General Hospital.

A panel of experts at the SLEEP 2022 conference argued against considering race a risk factor for health complications and disrupted sleep, saying that being on the receiving end of racial discrimination is the true risk factor.

Kim A. Reiss, MD, assistant program director of the Hematology/Oncology Fellowship Program and assistant professor of medicine at the Hospital of the University of Pennsylvania, discusses pancreatic cancer research she presented at the 2022 American Society of Clinical Oncology Annual Meeting.

Joel W. Neal, MD, PhD, associate professor, Division of Oncology, Stanford Cancer Institute, is lead investigator on the COSMIC-021 trial, which is investigating cabozantinib plus atezolizumab vs cabozantinib alone in patients with advanced non–small cell lung cancer (NSCLC) as a possible second-line treatment beyond chemotherapy.

Results presented at the American Society of Clinical Oncology Annual Meeting showed a 21.4-month advantage for autologous stem cell transplant (ASCT) over a common triplet therapy in progression-free survival (PFS) but no advantage in overall survival (OS).

Practice-changing data from the DESTINY-Breast04 study, presented during the 2022 Annual Meeting of the American Society of Clinical Oncology in Chicago, show that trastuzumab deruxtecan reduced the risk of disease progression or death by 50% compared with chemotherapy for human epidermal growth factor receptor-2 (HER2)–low patients with both hormone receptor (HR)–positive and HR-negative disease.

Thanos Zomas, MD, global medical lead, Lymphoma and Leukemia, and global medical lead, Adcetris Program, at Takeda Oncology discusses updated results from the ECHELON-1 study.

Posters from the SLEEP 2022 conference revealed some of the interaction between idiopathic hypersomnia and different aspects of life, including weight changes and interpersonal relationships.

David R. Penberthy, MD, MBA, is medical director, Radiation Oncology, Bon Secours-Southside Medical Center in Petersburg, Virginia, and president of the Association of Community Cancer Centers for the 2022-2023 term.

TROPiCS-02, a phase 3 study, was presented during a session on breast cancer at the 2022 Annual Meeting of the American Society of Clinical Oncology.

Kashyap Patel, MD, CEO of Carolina Blood and Cancer Care Associates, current president of the Community Oncology Alliance, and associate editor of Evidence-Based Oncology™, discusses his partnership with Sema4 and LabCorp and their joint goal to advance whole-exome sequencing (WES) for targeted oncology treatment.

Enrique Ocio, MD, PhD, hematology department head, Marqués de Valdecilla University Hospital, Santander, Spain, discusses phase 1b trial results for subcutaneous (sub-Q) vs intravenous isatuximab, both formulations administered in combination with pomalidomide and dexamethasone for relapsed/refractory multiple myeloma (RRMM).

The collaboration, put in place through a Memorandum of Understanding, was presented Saturday in a keynote address by WHO Cancer Control Officer André Ilbawi, MD, during the presidential symposium at the 2022 American Society of Clinical Oncology (ASCO) Annual Meeting taking place in Chicago.

Data presented at ASCO show that after 6 years, patients with advanced Hodgkin lymphoma who were treated with a combination of brentuximab vedotin and chemotherapy had a sharply reduced risk of death and a reduced risk of a secondary cancer.

Findings from the phase 3 SHINE trial could make ibrutinib the standard treatment option for older patients with mantle cell lymphoma (MCL), who often cannot tolerate chemotherapy or transplant strategies, according to study authors.

For the second year, the meeting will focus on health equity, as American Society of Clinical Oncology (ASCO) President Everett Vokes, MD, FASCO, has selected the theme “Advancing Equitable Cancer Care Through Innovation.”