April 28th 2025
New research suggests classical biomarkers cannot discriminate between refractory and non-refractory rheumatoid arthritis.
Comparable, Sustained Efficacy Observed With HNS vs PAP Therapy in OSA
December 15th 2021Patients with obstructive sleep apnea (OSA) exhibited similarly improved insomnia and quality-of-life outcomes when administered hypoglossal nerve stimulation (HNS) vs standard-of-care positive airway pressure (PAP) therapy.
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From Challenges Spring Opportunities for Progress in Daratumumab-Based Clinical Pathways
December 14th 2021An abstract presented at the 63rd Annual American Society of Hematology Annual Meeting and Exposition shows that although daratumumab use in multiple myeloma holds great promise, challenges remain in the use of clinical pathways for treatment direction with the monoclonal antibody—which the investigators say may also present opportunities for change.
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Dr Frederick Locke on Real-World Implications of ZUMA-7 Findings in Relapsed/Refractory LBCL
December 13th 2021Frederick Locke, MD, vice chair, Department of Blood and Marrow Transplant and Cellular Immunotherapy Program, co-leader, Immuno-Oncology, Moffitt Cancer Center, discusses findings of the phase 3 ZUMA-7 trial presented at ASH 2021 and how use of axicabtagene ciloleucel can be optimally applied in a real-world setting.
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Most Medicare Beneficiaries With CLL Diagnosis Don’t Get Therapy, Claims Analysis Finds
December 13th 2021Two-third of those who receive a chronic lymphocytic leukemia (CLL) diagnosis are age 65 or older, so the ease with which drugs are covered in Medicare has an outsized role in patient access to care.
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Educational Interventions Are Needed to Address Knowledge Gaps for Management of NASH
December 13th 2021Two posters presented at The Liver Meeting identified the primary care coordinators for patients with nonalcoholic steatohepatitis (NASH) and areas of unmet need among specialists to provide optimal management.
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Dr Mark Wildgust Reviews Key Cilta-Cel Research Presented at ASH 2021
December 13th 2021Mark Wildgust, PhD, vice president, Global Medical Affairs, Oncology, Janssen, speaks on progression-free survival, complete response, and overall survival benefits observed with ciltacabtagene autoleucel (cilta-cel) in CARTITUDE-1 and other studies presented at the 63rd Annual American Society of Hematology Meeting and Exposition.
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Uptake of Artificial Pancreas Systems in Primary Care Could Reduce Care Disparities
December 11th 2021Findings about the willingness of primary care providers to prescribe artificial pancreas systems have positive implications for increasing access to and reducing disparities around this technology by alleviating the need to see a specialist.
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Commentary Explores the Use of High-Flow Nasal Therapy in Patients With AECOPD
December 11th 2021High-flow nasal therapy overcomes some of the barriers associated with noninvasive ventilation, making the novel support beneficial for patients with acute exacerbations of chronic obstructive pulmonary disease (COPD).
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Dr Andre Goy Previews Key Data on CAR T-Cell Therapy to Be Presented at ASH 2021
December 10th 2021Andre Goy, MD, MS, chairman and executive director of the John Theurer Cancer Center, provides an overview of the emerging data at ASH 2021 on CAR T-cell therapy as a second- and first-line treatment.
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This article describes the Philadelphia Medicaid Opioid Prescribing Initiative that was launched by a multidisciplinary team and mailed local Medicaid providers individualized prescribing report cards.
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Patients With Psoriatic Disease May Have Greater Risk of VTE, PVD
December 6th 2021Patients with psoriasis were found to have a more than 20% increased risk of developing incident venous thromboembolism (VTE) and peripheral vascular disease (PVD), with notable at-risk groups including women and those with concomitant psoriatic arthritis.
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Brodalumab Improves Skin Clearance, QOL vs Ustekinumab in Comorbid Psoriasis, PsA
December 2nd 2021Patients with concomitant psoriasis and psoriatic arthritis (PsA) were shown to be 3.1-fold more likely to achieve complete skin clearance when treated with brodalumab vs ustekinumab after 52 weeks, with further improvements reported for quality of life (QOL).
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PCOS May Predispose Women to Higher Risk of Psychosis, Study Suggests
December 1st 2021This new study from Finland highlights both the potential for severe psychiatric disturbances among women with polycystic ovary syndrome (PCOS) and lack of extensive knowledge of the toll of psychoses among this group.
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Dupilumab-Induced Ophthalmic Disease Common in Adults With Atopic Dermatitis
December 1st 2021More than 1 in 3 patients with atopic dermatitis reported incidence of dupilumab-induced ocular surface disease (DIOSD), with asthma and family history of AD shown to further increase the risk of developing DIOSD.
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TNF Inhibitors Show Real-world Efficacy on QOL of Patients With Nail Psoriasis, PsA
November 29th 2021Patients with concomitant psoriasis, nail psoriasis, and psoriatic arthritis (PsA) exhibited significant improvements in joint and disease severity symptoms, as well as quality of life (QOL) after 3 months of treatment with tumor necrosis factor-α (TNF) inhibitors of adalimumab, etanercept, or infliximab.
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President Joe Biden will provide an update today on his administration’s response to the Omicron COVID-19 variant; marked rise in lung transplants for patients with COVID-19 sparks ethical questions; an independent panel of experts will advise FDA tomorrow on the use of Merck’s COVID-19 antiviral pill.
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