All News

Evidence is insubstantial for treatment of Clostridioides difficile infection (CDI), but authors of a review of available evidence provide recommendations for agents and testing.

Several biomarkers identified by comprehensive genomic profiling were found to predict efficacy and toxicity of chemo-radiotherapy in patients with non–small cell lung cancer (NSCLC), with progression-free survival and overall survival outcomes associated with some of the identified genes.

Investigators compared physical and mental health outcomes among infertile women with and without polycystic ovary syndrome (PCOS), who were considered obese, by looking at their dietary intake, eating behavior, physical activity levels, and quality of life (QOL).

Researchers in Italy found parental stress levels are correlated with the severity of their child's migraine condition.

A study suggests tumor in situ fluid is a better choice when trying to extract tumor DNA in patients with glioma who underwent surgery.

The life expectancy in the United States dropped sharply during 2020; the United Kingdom has approved the first COVID-19 antiviral pill; a government advisory panel recommends all US adults younger than 60 years be vaccinated against hepatitis B.

Children with severe atopic dermatitis were shown to be at nearly 2-fold greater risk of both depression and internalizing behaviors, with mild disease also associated with internalizing behaviors in those as young as 4 years of age.

Cost increases were particularly pronounced among patients with severe systemic lupus erythematosus (SLE), the study found.

New data show the therapy led to minimal changes in renal function, even after more than 8 years.

Helen Bygrave, MD, chronic diseases advisor for the Médecins Sans Frontières (MSF; Doctors Without Borders) Access Campaign, explains how the campaign is aiming to eliminate the threat of cryptococcal meningitis among persons living with HIV by 2030.

A greater proportion of biologic-naive patients with psoriatic arthritis treated with ixekizumab vs adalimumab achieved the combined endpoint of 100% resolution in the Psoriasis Area Severity Index and 50% or greater improvement in the American College of Rheumatology criteria at week 24 and 52.

Two analyses presented at the Academy of Managed Care Pharmacy Nexus 2021 meeting highlighted the safety and cost benefits of tazemetostat compared with phosphoinositide 3 (PI3) kinase inhibitors for patients with follicular lymphoma.

The CDC director endorsed a pediatric Pfizer COVID-19 vaccine for children aged 5 to 11 years; proposed drug pricing reform will allow Medicare Part D to negotiate directly with pharmaceutical companies; some employers may not send death benefits to families of employees who die of COVID-19 without being vaccinated.

To help close health equity gaps, CMS finalized a rule that will update payment rates and improve incentives for providers to encourage them to increase access to home dialysis and kidney transplants for low-income patients with end-stage renal disease.

Patients with multiple sclerosis (MS) had similar factors associated with adverse COVID-19 outcomes vs other populations, but these risks were found to decrease with subsequent COVID-19 waves, investigators found.

Results of a longitudinal study indicate community food accessibility factors may impact type 2 diabetes risk among veterans.

On this episode of Managed Care Cast, we speak with one of the coauthors of a study that illustrates the changing outpatient trends in a primary care provider’s (PCP) panel of Medicare patients and how that translates to an increased workload for primary care doctors.

Individuals with a history of acute myocardial infarction (AMI), or heart attack, may benefit on several fronts following early administration of the neprilysin inhibitor/angiotensin receptor blocker sacubitril/valsartan.

A genetic biomarker test for patients with aggressive prostate cancer was found to identify which patients are more likely to respond to radiation and hormone treatments or develop metastases, allowing providers to personalize therapy regimens for high-risk patients.

An abstract presented at CHEST 2021 showed that women who entered pregnancy with sleep-disordered breathing were associated with higher levels of insulin resistance and potential risk of gestational diabetes.

California judge rules Allergan, Endo, Johnson & Johnson, and Teva not liable for state's opioid crisis; CDC panel to decide on approval of and recommendations for Pfizer/BioNTech's COVID-19 vaccine in children aged 5 to 11 years; screen time among teenagers more than doubled during the pandemic.

Patients treated with immune checkpoint inhibitors had significantly different survival rates based on the test, regardless of PD ligand 1 classification.

The August telehealth growth coincided with the peak of the surge in COVID-19 cases driven by the Delta variant in the South.

Robert A. Gabbay, MD, PhD, chief scientific and medical officer at the American Diabetes Association (ADA), talks about the "old-fashioned" finger stick requirement for continuous glucose monitoring.

Pharmacy experts from IPD Analytics explained the potential for authorized biologics, which would compete, potentially on the same price footing, with biosimilars.

The review found an association between systemic inflammatory disorders and increased risk of cardiovascular disease, encouraging discussions with patients regarding statin therapy.

The analysis found 20% of people with asthma, emphysema, or chronic bronchitis also have depression.

Video game therapy was found to have a minor impact on postural balance in patients with multiple sclerosis (MS); however, more research is needed to determine whether it should be recommended in clinical practice, investigators concluded.

Patients with pulmonary arterial hypertension (PAH) taking spironolactone saw a reduced risk of morbidity and mortality when receiving macitentan 10 mg.

The 2021 ACAAI Annual Scientific Meeting, taking place virtually and in person in New Orleans, kicks off on Thursday, November 4, by focusing on dermatology and atopic dermatitis and concludes on Monday, November 8, with a final plenary session that addresses updates to several treatment guidelines.