All News

If FDA approved for children, secukinumab (Cosentyx) will be the first biologic treatment for children in the US living with enthesitis-related arthritis.

An overview of activities at the FDA to promote the use of biosimilars was presented by Jacqueline Corrigan-Curay, JD, MD, principal deputy center director for the Center for Drug Evaluation and Research (CDER) at the FDA.

Findings of a real-world, single-center study indicated that apremilast was effective and safe long-term in the treatment of moderate-to-severe plaque psoriasis.

This cohort study of women living with HIV, pregnant and not pregnant, investigated outcomes related to engagement in HIV care following a live birth.

The analysis showed biomarkers that persisted despite the presence or absence of type-2 inflammation.

On this episode of Managed Care Cast, we speak with Abi Sundaramoorthy, MD, MBA, executive vice president of clinical enterprise at Somatus, on fragmented care in chronic kidney disease, its disproportionate impact on minority communities, and the potential of value-based arrangements to address disparities and promote preventive, effective care.

The parameter could potentially help clinicians zero in on the cause of left ventricular hypertrophy.

Pfizer and BioNTech expect to seek emergency use authorization for their COVID-19 booster vaccine in all adults 18 years and older; the Biden administration urges appeals court to not block employer vaccine mandate; nearly 8 in 10 Americans believe or are unsure of false COVID-19 information.

The American Society of Ophthalmic Plastic & Reconstructive Surgery 2021 Fall Scientific Symposium will feature presentations on oculofacial surgery innovations, social justice and diversity, and more.

Jonathan Silverberg, MD, PhD, MPH, associate professor of dermatology, director of clinical research and patch testing, George Washington University School of Medicine and Health Sciences, discusses the involvement of the JAK/STAT pathway in the pathogenesis of atopic dermatitis.

Joseph Mikhael, MD, of the Translational Genomics Research Institute in Phoenix, Arizona, an affiliate of City of Hope, spoke with The American Journal of Managed Care® about the increased use of triplet therapy to treat this disease.

Most adverse events in trials of adenosine triphosphate (ATP) blockers for chronic cough are related to taste, which may inadvertently cause the studies to become unblinded to patients, and a way of measuring this to know the extent of the problem is needed, said Ron Eccles, BSc, PhD, DSc, emeritus professor at Cardiff University.

Patients with lupus nephritis (LN) were found to have as much as twice the inpatient hospitalizations of patients with systemic lupus erythematosus without LN.

Researchers outlined the need to combat underrepresentation of racial minorities in pulmonary arterial hypertension (PAH) registries and trials.

Research presented at Kidney Week 2021 suggests sodium-glucose co-transporter 2 inhibitors may show beneficial cardiovascular (CV) and kidney effects among patients with type 1 diabetes.

Hospitalization for an acute kidney injury (AKI) event was identified as a risk factor for several adverse events after hospital discharge, including hospital readmission and mortality, according to findings presented at Kidney Week 2021.

Findings of an abstract presented at CHEST 2021 indicated that antidepressant use was associated with increased REM sleep latency and a complete lack of REM sleep, which may contribute to the poorer quality-of-life scores observed in these patients.

More research is needed to better understand the potential therapeutic benefits of ketamine among migraineurs, concluded authors of a systematic review and meta-analysis.

Results of a cross-sectional study detail characteristics among women with polycystic ovary syndrome (PCOS) who develop type 2 diabetes.

The United States lifts travel restrictions for numerous countries, requiring proof of vaccination and in some cases negative COVID-19 tests; discrimination of any kind was associated with greater risk of mental health problems in young people; a controversial Alzheimer disease drug faces several uptake issues.

Richard Wasserman, MD, PhD, an allergist and immunologist with Allergy Partners of North Texas, an early adopter of food allergy oral immunotherapy (OIT), discusses how attitudes have changed around the practice.

To avoid bankrupting health care, providers must carefully consider how they use biologics in patients with severe asthma, according to a presenter at the American College of Allergy, Asthma & Immunology Annual Scientific Meeting.

James Auran, MD, a professor of ophthalmology at Columbia University Irving Medical Center and president of the American Society of Ophthalmic Trauma, explains what he is most looking forward to at the 2021 conference of the American Academy of Ophthalmology (AAO).

David Ramsey, MD, PhD, MPH, previews a session at the American Academy of Ophthalmology 2021 conference that explores whether telehealth visits among patients with diabetes affected rates of completed in-person eye examinations.

Conference abstracts explored the relationship between serum phosphate levels on mortality in patients with chronic kidney disease (CKD) and cost burdens for employers as patients transition to end-stage renal disease.

While low- and middle-income countries remain desperate for a COVID-19 vaccine, the United States has entered a dangerous new phase of the pandemic, where antivaccine forces are exporting their antiscience beliefs to other countries, according to a keynote speaker at the American College of Allergy, Asthma & Immunology Annual Scientific Meeting.

Choice of therapy to manage multiple sclerosis (MS) and prevent relapse was found to influence radiological and laboratory results, including lesion presentation, giving insight into the paraclinical characteristics of patients receiving different MS therapies.

The American Academy of Ophthalmology conference is scheduled to take place in-person and online from November 12-15, 2021.

Ignoring life-threatening, non–COVID-19 conditions for too long can turn one health crisis into another. Now is the time to resume cancer screenings, like mammograms and colonoscopies, because early detection can be lifesaving.

Carina Venter, PhD, RD, allergy specialist dietitian and associate professor in pediatric allergy and immunology at Children's Hospital Colorado and the University of Colorado, discusses the gut microbiome’s complex relationship with our immune system and diet diversity’s potential role in allergic disease and food allergy–related outcomes.