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Pfizer predicts that a fourth dose of a COVID-19 vaccine may be needed to quell the Omicron variant; CMS officials share figures on enrollment for health coverage under the Affordable Care Act (ACA); City of Hope announces acquisition of Cancer Treatment Centers of America.

High-intensity interval training (HIIT) may maintain health, including immune cell function, for patients with treatment-naïve chronic lymphocytic leukemia (CLL).

Nail involvement was shown to reduce the effectiveness of ustekinumab in the treatment of moderate to severe psoriasis, whereas secukinumab exhibited overall higher efficacy than ustekinumab and similar response rates regardless of nail involvement.

Children aged 6 to 11 years had reduced asthma exacerbations and improved lung function and asthma control when on dupilumab for a year.

Financial hardship was found to be a significant risk factor for worse sleep quality in patients with concomitant obstructive sleep apnea (OSA) and type 2 diabetes (T2D)

Limited access to exercise equipment and facilities during lockdown appears to be a key reason for reduced physical activity levels.

The FDA approved FoundationOneCDx as the first companion diagnostic for current and future BRAF inhibitor therapeutics used to treat melanoma, including both monotherapies and combination therapies.

Results of a retrospective cohort study show youth with type 2 diabetes were almost twice as likely to develop retinopathy compared with those with type 1 diabetes.

Results of a cross-sectional study fond diabetic kidney disease (DKD) was associated with retinal changes in patients with type 2 diabetes (T2D).

Antibodies produced by vaccinated people may be less successful at fighting against Omicron compared with other variants; Congressional leaders created a plan to lift the debt limit with only Democratic votes in the Senate, staving off Medicare cuts; cases of depression and anxiety among youths both doubled during the pandemic.

Costs of extending human epidermal growth factor receptor 2 (HER2) therapy for patients with metastatic breast cancer were estimated in a retrospective study.

Patients who took supplements had improvements, although they did not become apparent until patients had been taking supplements for a year.

Children with uncontrolled asthma had a 3- to 6-times the risk of hospitalization for COVID-19, the investigators found.

A secondary analysis of economic outcomes–related data from the Rehabilitation Therapy in Older Acute Heart Failure Patients trial attempted to answer if a novel 12-week rehabilitation intervention held cost-effective value.

Male and female patients with acne vulgaris have been found to have significantly different dysbiosis of gut microbiota and associated metabolites.

Children with atopic dermatitis were shown to be at an increased risk of fractures compared with the general population, with systemic use of corticosteroid and antihistamine therapy cited as mediating factors.

This new study investigated a potential link between genetically predicted polycystic ovary syndrome (PCOS) and greater risk of endometrial cancer among patients of European and Asian ancestries.

On this episode of Managed Care Cast, guests discuss why pharmacists are in a unique position to help address social determinants of health (SDOH) and the importance of incorporating patients’ perspectives into research agendas.

Investigators hope to duplicate promising phase 2b trial results with an experimental peptide vaccine in a population of nearly 500 patients with human epidermal growth factor receptor 2 breast cancer.

Fifty-one therapies have been approved for rare neurological diseases since the FDA passed the Orphan Drug Act in 1983.

The proportions of children and adolescents living with HIV who have achieved viral suppression after antiretroviral therapy initiation were consistently lower than those of adults.

British study finds higher immune response when mixing Pfizer, AstraZeneca COVID-19 vaccines with Moderna; World Health Organization strongly advises against the use of convalescent plasma to treat COVID-19; disparities in pay by gender among physicians.

Real-world evidence from Japan found ixazomib has an acceptable safety profile in patients with relapsed/refractory multiple myeloma (RRMS).

Opinions on the effectiveness and usefulness of telehealth services varied among clinicians and older patients with chronic kidney disease (CKD), suggesting that new measures and training programs should be put in place to mitigate disparities and accessibility issues.

Patients with psoriasis were found to have a more than 20% increased risk of developing incident venous thromboembolism (VTE) and peripheral vascular disease (PVD), with notable at-risk groups including women and those with concomitant psoriatic arthritis.

A cross-sectional study using data from United Kingdom Biobank found that migraine is gender-dependently associated with physically demanding jobs and shift work.

Patients with SLE had higher levels of Wnt5A if they were experiencing active disease.

Results of a systemic review found evidence potentially supporting the use of smart phone applications among mothers with gestational diabetes.

Funmi Olopade, MD, FACP, professor of medicine and human genetics and founding director of the Center for Clinical Cancer Genetics and Global Health at the University of Chicago Medical Center, previews her keynote address for the San Antonio Breast Cancer Symposium (SABCS).

Aaron Lee, MD, an associate professor of ophthalmology at the University of Washington, explains why raising the standard of medical knowledge of artificial intelligence (AI) in ophthalmology is important.