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Samsung Bioepis found during a 5-year follow-up study that Ontruzant, the company’s trastuzumab biosimilar, had comparable cardiac safety and long-term efficacy with the reference product Herceptin.

Entresto (sacubitril/valsartan) was first approved for use in heart failure with reduced ejection fraction (HFrEF) in 2015.

Results of a Swedish retrospective cohort study showed reduced rates of type 1 diabetes-related amputations over the past 2 decades.

Eating or drinking less than 1 hour before bedtime was associated with increased risk of wake after sleep onset, a key symptom of chronic insomnia that significantly correlates with poor sleep quality.

Two posters being presented at the European Society for Medical Oncology Congress 2021 highlighted the need to provide long-term psychosocial support for adolescents who survive childhood leukemia.

Results of a cross-sectional study highlight the clinical features shared by bipolar disorder and migraine, and assesses characteristics of patients with both conditions.

On this episode of Managed Care Cast, we speak with the lead clinician of a study by the Epic Health Research Network and Kaiser Family Foundation, which found that routine medical care and hospital admissions remained below expected levels in the early months of 2021, marking the second consecutive year for such results.

The general public may not yet need COVID-19 booster doses, according to a new review; a significant incidence of anxiety tied to climate change and government inaction is being reported in young people; COVID-19 infections in US children have increased by approximately 240% since early July.

Psychological and emotional needs specific to populations with cancer are often overlooked in clinical research, including those of adolescents, young adults, immigrants, and people of lower socioeconomic status.

Patients with chronic liver diseases have been at a high risk of more severe COVID-19 outcomes, but the pandemic has meant the management of these diseases has received less attention.

Differentiated service delivery models can be employed to incorporate other chronic disease needs for patients with HIV, emphasized Helen Bygrave, MD, Médecins Sans Frontières (Doctors Without Borders).

In a panel at the 5th annual Heart in Diabetes Conference, John McMurray, MD, and Javed Butler, MD, highlighted recent pharmacological developments in heart failure (HF) and offered insights on overlooked areas in the field.

President Joe Biden plans to announce new steps aimed at curbing the spread of COVID-19; spotlighting the rise of unsubstantiated diagnoses and subsequent drugging in nursing homes; CDC report finds unvaccinated people are 11 times more likely to die from COVID-19.

Michael E. Wechsler, MD, a pulmonologist at National Jewish Health, discusses the conditions that can develop as a result of abnormal eosinophilic activity.

This new analysis of combination treatment with ipilimumab and nivolumab identified factors likely to lead to therapeutic success with the combination.

Innovative therapies for rare diseases such as spinal muscular atrophy (SMA), when paid for by public budgets in the European Union and elsewhere, are often managed by agreements between payers and drug companies, but details can be hard to discern.

From the decision analysis came an agreement that reimbursement for an orphan drug should be based primarily on its effect on health-related quality of life, its effectiveness, and the availability of other treatment options.

In pediatric patients with frequently relapsing nephrotic syndrome (FRNS), the therapy was well tolerated, but did not lead to significant changes in disease course.

According to researchers, new findings may have important implications for expanding the use of measurable residual disease (MRD) in multiple myeloma.

Investigators identified 5 mutated genes that could serve as biomarkers for disease prognosis and clinical outcomes associated with pancreatic ductal adenocarcinoma, a common cancer with a high mortality rate and poor prognosis.

Rajesh Rajpal, MD, chief medical officer, global head of clinical medical affairs, Johnson & Johnson Vision, discusses the surgical options available to patients undergoing cataract surgery.

Investigators examined medical records spanning 3 decades to look at the effect of poorly differentiated tumor size on outcomes in survival in hepatocellular carcinoma (HCC).

Adherence to continuous positive airway pressure (CPAP) resulted in a large decrease in insomnia and a significant reduction in prevalence of insomnia from baseline to follow-up in patients with obstructive sleep apnea.

Discontinued use and high dosage of alpha-glucosidase inhibitors in combination with metformin was shown to increase risk of psoriasis and psoriatic arthritis in patients with type 2 diabetes compared with those given only metformin.

Crigler-Najjar Syndrome Type 1 is an ultra-rare disease where treatment relies on a liver transplant or full-day phototherapy sessions.

A session at the 5th annual Heart in Diabetes Conference highlights the long-term risks of gestational diabetes.

Reducing the risks of secondary neutropenia, exposure to COVID-19, mortality, and financial toxicity were all major reasons the use of pegfilgrastim biosimilar gained traction during the pandemic, said Kashyap Patel, MD, CEO of Carolina Blood and Cancer Care.

In a recent study, researchers were able to show how different evolutionary forces in aging blood stem cells impact whether or not someone develops acute myeloid leukemia (AML), offering insight into those at higher risk of the disease.

An emphasis on transitions of care should ensure the highest level of care for patients and provide support to physicians.

New research presented at the 5th Heart in Diabetes Conference highlights potential therapeutic options for patients with COVID-19 and diabetes.