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According to a recent study, nearly 50% of patients with connective tissue disease, such as lupus, died when sepsis occurred.

One of the long-term effects of COVID-19 may be small fiber neuropathy in the ocular surface causing similar symptoms to dry eye disease and diabetic neuropathy, a recent study found.

In this column, an endocrinologist discusses the growing problem of liver disease and new options at their disposal, including vibration-controlled transient elastography.

Predictive markers may make it easier to figure out which patients require the often costly and invasive measures needed to confirm the coronary complication in patients with systemic lupus erythematosus.

Patients with chronic rhinosinusitis with nasal polyps were found to benefit more from the combination of endoscopic sinus surgery plus medical therapy vs medical therapy alone, although the minimal clinically important difference was not met.

Among the 3 methods used across 478 samples included in the study, next-generation sequencing provided the most favorable results.

A review of 3 common risk assessment tools for pulmonary arterial hypertension (PAH) found they successfully predict survival for up to 5 years after initial diagnosis.

In this recent CDC report, data show decreases in new HIV diagnoses in Lesotho, in Africa, among adolescent girls and young women attending antenatal care.

The severity of excessive daytime sleepiness correlated with the prevalence of Parkinsonian-like symptoms in adults aged 50 to 64, but further research is needed to determine the mechanisms behind the findings.

Among the most notable findings were that acute generalized exanthematous pustulosis is typically triggered by antimicrobial agents and may be associated with complications of the liver or kidney for some patients.

Edward W. Cowen, MD, MHSc, senior clinician and acting branch chief, Dermatology Branch, National Institutes of Health, speaks on cytokines involved in the pathophysiology in pustular psoriasis and off-label therapy use.

A nationwide study in Finland showed that the number of antibiotics and asthma drugs fell by 59.6% and 19.8%, respectively, from 2019 to 2020, generating millions in cost savings.

Researchers said they wanted to take a broad look at the level and scope of the disruption for those with Parkinson disease and dementia still living at home and compare the findings to before the pandemic.

Researchers have found that most US patent infringement cases against biosimilar manufacturers cover patents filed over a decade after the originator product's FDA approval, leading to limits on competition among biologic drugs.

Over the 24-year period, there were 57 spinal muscular atrophy diagnoses in 53 families, and a disease birth prevalence of 1 per 8286 births in Estonia.

Throughout their paper, researchers highlighted acne treatment for these patients often involves other considerations—including reproductive health and mental health—and dermatologists should keep these in mind when making decisions for each patient.

Given the heterogeneous nature of breast cancer, biomarkers evaluated throughout treatment help provide a clearer picture of the treatment paradigm.

Patients with atopic dermatitis were associated with significant economic burden primarily driven by outpatient visits and pharmacy use, which increased with disease severity.

Unvaccinated older adults are 49 times more likely to be hospitalized after contracting COVID-19; nursing homes are experiencing a major staffing crisis; major Alzheimer groups plan to meet with federal officials and lawmakers to protest the CMS drug proposal.

Coverage of our peer-reviewed research and news reporting in the health care and mainstream press.

For the first time, a major study showed that remission for peanut allergy can be achieved even in very young children using oral immunotherapy.

More nutritional care may be needed for elderly patients with chronic kidney disease (CKD) who are ingesting higher-than-recommended amounts of protein, investigators concluded.

Recent research suggests targeted memory reactivation might help with facial recognition and name recall, but quality and quantity of sleep may be important factors in effectiveness.

The frequency of several mutations that inhibit response to tyrosine kinase inhibitors and tend to lead to increased disease severity was elevated in Chinese patients with non-small cell lung cancer.

Results of a study conducted among Finnish migraineurs highlight a link between the condition and hypertension.

In a small study, evidence suggested 8-Hydroxy-2'-deoxyguanosine levels negatively correlated with a test of exercise endurance.

Drug makers sign on to help produce Merck’s COVID-19 pill for developing countries; research shows promise for organ transplants from genetically modified pigs; blood sample collection tubes added to FDA list of shortages.

Patients whose endurance increases will likely have a higher quality of life and ability to carry out daily functions, the authors said.

On this episode of Managed Care Cast, we interview the lead author of a paper in the Health IT issue of The American Journal of Managed Care.

Zanubrutinib is a second-generation Bruton tyrosine kinase (BTK) inhibitor that has fewer off-target effects and less cardiotoxicity than ibrutinib, a first-generation BTK inhibitor.